refractory multiple myeloma
Item
diagnosed with multiple myeloma that is refractory or has relapsed after treatment
boolean
C0026764 (UMLS CUI [1,1])
C0205269 (UMLS CUI [1,2])
m-protein serum, urine
Item
measurable serum and/or urine m-protein
boolean
C0700271 (UMLS CUI [1,1])
C0229671 (UMLS CUI [1,2])
C0042036 (UMLS CUI [1,3])
multiple myeloma failed therapies
Item
failed 1 or 2 prior therapies for multiple myeloma
boolean
C0026764 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C023117 (UMLS CUI [1,3])
age
Item
18 years of age or older
boolean
C0001779 (UMLS CUI [1])
multiple myeloma prior therapies
Item
received more than 2 prior therapies for multiple myeloma.
boolean
C0026764 (UMLS CUI [1,1])
C1514463 (UMLS CUI [1,2])
previous cancer therapy
Item
previous cancer therapies (chemotherapy, biologic therapy, radiation therapy or immunosuppressants) within the last 3 weeks
boolean
C1514463 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
monoclonal antibodies
Item
received monoclonal antibodies within the last 3 weeks (chimeric or murine) or 8 weeks (human or humanized)
boolean
C0003250 (UMLS CUI [1])
multiple myeloma investigational agent
Item
received investigational (not yet approved by a regulatory authority) agent to treat multiple myeloma within the last 4 weeks
boolean
C0026764 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
autologous stem cell transplant
Item
subjects who received a stem cell transplant using cells from themselves in the past 16 weeks
boolean
C1831743 (UMLS CUI [1])
allogeneic stem cell transplant
Item
subjects who received a stem cell transplant using cells from another individual
boolean
C2242529 (UMLS CUI [1])
bortezomib, mapatumumab
Item
previously treated with bortezomib or mapatumumab
boolean
C1176309 (UMLS CUI [1])
C1665688 (UMLS CUI [2])
hiv, hepatitis a, b, c
Item
known hiv, hepatitis-b, hepatitis-c, or hepatitis a infection
boolean
C0019682 (UMLS CUI [1])
C0019159 (UMLS CUI [2])
C0019163 (UMLS CUI [3])
C0019196 (UMLS CUI [4])
infections, antibiotics, hospitalization
Item
infection requiring antibiotics or hospitalization within the last 2 weeks
boolean
C0009450 (UMLS CUI [1,1])
C0003232 (UMLS CUI [1,2])
C0019993 (UMLS CUI [1,3])
major surgery
Item
major surgery within the last 4 weeks
boolean
C0679637 (UMLS CUI [1])
poems syndrome
Item
diagnosis with poems syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes)
boolean
C0085404 (UMLS CUI [1])
other cancer
Item
history of other cancers within the past 5 years
boolean
C0006826 (UMLS CUI [1])
pregnancy, breast feeding
Item
pregnant or breast-feeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])