Diabetes Mellitus, Non-Insulin-Dependent
Item
must have been diagnosed with type 2 diabetes at least three months prior to screening.
boolean
C0011860 (UMLS CUI [1])
Metformin Dose Stable | Sulfonylurea Dose Stable | Insulin Dose Stable
Item
must be taking either metformin and a sulfonylurea, metformin and insulin, or insulin only, and doses of these medications must have been stable for at least three months.
boolean
C0025598 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0038766 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0021641 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0205360 (UMLS CUI [3,3])
Body mass index
Item
must have a body mass index (bmi) of between 24 and 35.
boolean
C1305855 (UMLS CUI [1])
Postmenopausal state
Item
if female, the subject must be post-menopausal.
boolean
C0232970 (UMLS CUI [1])
Glucohemoglobin measurement
Item
hba1c levels must be between 7% and 10%.
boolean
C0202054 (UMLS CUI [1])
Patient eligible Magnetic Resonance Imaging | Implants Metallic Absent | Artificial cardiac pacemaker Absent
Item
subjects must be eligible for mri scanning (ie, no metal implants, pacemaker, etc).
boolean
C0030705 (UMLS CUI [1,1])
C1548635 (UMLS CUI [1,2])
C0024485 (UMLS CUI [1,3])
C0021102 (UMLS CUI [2,1])
C2986473 (UMLS CUI [2,2])
C0332197 (UMLS CUI [2,3])
C0030163 (UMLS CUI [3,1])
C0332197 (UMLS CUI [3,2])
Claustrophobia
Item
suffer from claustrophobia.
boolean
C0008909 (UMLS CUI [1])
Tobacco use | DRUG ABUSE ILLICIT
Item
use of tobacco, nicotine, or illegal drugs of abuse.
boolean
C0543414 (UMLS CUI [1])
C0743253 (UMLS CUI [2])
caffeine use
Item
use of caffeine within two days prior to each study visit.
boolean
C2006086 (UMLS CUI [1])
HIV Infection | Hepatitis | Edema | Blood pressure problem untreated | Heart Disease | Lung disease | nervous system disorder | Kidney Disease | Blood Clot Lower Extremity | Diabetic Neuropathy | Thyroid Disease untreated
Item
hiv, hepatitis, edema, untreated blood pressure problems, heart, lung, nervous system or kidney disease, history of blood clots in the legs, diabetic neuropathy, or untreated thyroid disease.
boolean
C0019693 (UMLS CUI [1])
C0019158 (UMLS CUI [2])
C0013604 (UMLS CUI [3])
C0848910 (UMLS CUI [4,1])
C0332155 (UMLS CUI [4,2])
C0018799 (UMLS CUI [5])
C0024115 (UMLS CUI [6])
C0027765 (UMLS CUI [7])
C0022658 (UMLS CUI [8])
C0302148 (UMLS CUI [9,1])
C0023216 (UMLS CUI [9,2])
C0011882 (UMLS CUI [10])
C0040128 (UMLS CUI [11,1])
C0332155 (UMLS CUI [11,2])
Pharmaceutical Preparations Affecting Body Fluid Level | Diuretics
Item
use of drugs or medications that affect the levels of fluid in the body, such as diuretics.
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005889 (UMLS CUI [1,3])
C0441889 (UMLS CUI [1,4])
C0012798 (UMLS CUI [2])