Non-alcoholic Fatty Liver Disease | Study Subject Participation Status
Item
histological evidence of nafld and enrollment in nash crn database study
boolean
C0400966 (UMLS CUI [1])
C2348568 (UMLS CUI [2])
Diabetes Mellitus, Non-Insulin-Dependent | Diet therapy | Oral hypoglycemic Dose Stable
Item
type 2 dm treated with diet or a stable dose of non-insulin sensitizing oral hypoglycemic agents for > 3 mo.
boolean
C0011860 (UMLS CUI [1])
C0012159 (UMLS CUI [2])
C0359086 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0205360 (UMLS CUI [3,3])
Glucohemoglobin measurement
Item
hemoglobin hba1c level ≤ 8 %
boolean
C0202054 (UMLS CUI [1])
Alanine aminotransferase measurement
Item
serum alt levels ≥1.3 x uln
boolean
C0201836 (UMLS CUI [1])
Age
Item
between 18-65 years of age
boolean
C0001779 (UMLS CUI [1])
Hereditary hemochromatosis | Iron Overload Hepatic
Item
hereditary hemochromatosis or hepatic iron overload defined as any of the following:
boolean
C0392514 (UMLS CUI [1])
C0282193 (UMLS CUI [2,1])
C0205054 (UMLS CUI [2,2])
Iron Positive | Iron Hepatic Staining
Item
2+ iron on hepatic iron staining
boolean
C0302583 (UMLS CUI [1,1])
C1514241 (UMLS CUI [1,2])
C0302583 (UMLS CUI [2,1])
C0205054 (UMLS CUI [2,2])
C0487602 (UMLS CUI [2,3])
Hepatic iron index
Item
hepatic iron index ≥ 1.9
boolean
C1954806 (UMLS CUI [1])
hfe gene c282y variant | hfe gene h63d variant
Item
c282y homozygous or c282y/h63d compound heterozygous hfe genotype
boolean
C3468755 (UMLS CUI [1])
C3468756 (UMLS CUI [2])
Insulin | Thiazolidinediones | Diabetes Therapy
Item
use of insulin or thiazolidinediones for the treatment of diabetes
boolean
C0021641 (UMLS CUI [1])
C1257987 (UMLS CUI [2])
C3274787 (UMLS CUI [3])
Pharmaceutical Preparations Against Nonalcoholic Steatohepatitis | Thiazolidinediones | Vitamin E | Ursodiol | S-Adenosylmethionine | Betaine | Milk thistle extract | Gemfibrozil | anti-tumor necrosis factor therapy | Probiotics
Item
use of anti-nash drugs (thiazolidinediones, vitamin e, udca, sam-e, betaine, milk thistle, gemfibrozil, anti-tnf therapies, probiotics)
boolean
C0013227 (UMLS CUI [1,1])
C0521124 (UMLS CUI [1,2])
C3241937 (UMLS CUI [1,3])
C1257987 (UMLS CUI [2])
C0042874 (UMLS CUI [3])
C0042105 (UMLS CUI [4])
C0036002 (UMLS CUI [5])
C0005304 (UMLS CUI [6])
C0937640 (UMLS CUI [7])
C0017245 (UMLS CUI [8])
C0281481 (UMLS CUI [9])
C0525033 (UMLS CUI [10])
Serum ferritin measurement
Item
serum ferritin <50μg/l
boolean
C0696113 (UMLS CUI [1])
Transferrin saturation measurement
Item
serum transferrin-iron saturation <10 %
boolean
C1277709 (UMLS CUI [1])
Hemoglobin measurement
Item
hemoglobin <10 mg/l
boolean
C0518015 (UMLS CUI [1])
Hematocrit level
Item
hematocrit <38 %
boolean
C0518014 (UMLS CUI [1])
Blood Donation Voluntary | Venesection
Item
voluntary blood donation or therapeutic phlebotomy within the previous twelve months (except routine lab tests)
boolean
C0005794 (UMLS CUI [1,1])
C0439656 (UMLS CUI [1,2])
C0684257 (UMLS CUI [2])
Pregnancy | Breast Feeding
Item
pregnant or lactating women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Coronary Artery Disease | Myocardial Infarction | Dyspnea on exertion | Chest pain at rest chronic
Item
prior history of coronary artery disease, myocardial infarction, exertional dyspnea or chronic chest pain at rest.
boolean
C1956346 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0231807 (UMLS CUI [3])
C0392685 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
Electrocardiogram: myocardial infarction
Item
evidence of myocardial infarction as determined by an ecg
boolean
C0428953 (UMLS CUI [1])