Age
Item
males and females, 18 or older
boolean
C0001779 (UMLS CUI [1])
Chronic-Phase Myeloid Leukemia Philadelphia chromosome positive | Chronic myelogenous leukemia, BCR/ABL positive
Item
chronic phase ph+ or bcr-abl positive cml
boolean
C0023474 (UMLS CUI [1,1])
C0856536 (UMLS CUI [1,2])
C1292771 (UMLS CUI [2])
imatinib | Complete Hematologic Response
Item
current complete hematologic response to imatinib
boolean
C0935989 (UMLS CUI [1])
C4050175 (UMLS CUI [2])
Molecular Major Response Lacking
Item
lack of major molecular response
boolean
C4049637 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
imatinib Duration
Item
on imatinib for at least one year
boolean
C0935989 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
imatinib Dose Same Duration
Item
on the same imatinib dose for at least 6 months
boolean
C0935989 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0445247 (UMLS CUI [1,3])
C0449238 (UMLS CUI [1,4])
Liver function | Renal function
Item
adequate hepatic and renal function
boolean
C0232741 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
Leukemia, Myeloid, Accelerated Phase | Blast Phase
Item
history of accelerated or blast phase cml
boolean
C0023472 (UMLS CUI [1])
C0005699 (UMLS CUI [2])
Disease Uncontrolled Serious | Communicable Disease
Item
serious uncontrolled medical disorder or active infection
boolean
C0012634 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
C0205404 (UMLS CUI [1,3])
C0009450 (UMLS CUI [2])
Cardiovascular Disease | Blood Coagulation Disorder
Item
significant cardiovascular disease or bleeding disorder
boolean
C0007222 (UMLS CUI [1])
C0005779 (UMLS CUI [2])
Pharmaceutical Preparations At risk Causing Torsades de points
Item
concurrent use of medications at risk of causing torsades de pointe
boolean
C0013227 (UMLS CUI [1,1])
C1444641 (UMLS CUI [1,2])
C0678227 (UMLS CUI [1,3])
C3842160 (UMLS CUI [1,4])