Leukemia, Myelocytic, Acute | Myelosuppressive Chemotherapy | Age | Comorbidity | Acute Myelocytic Leukemia Relapse | Standard therapy refractory | Cytoreductive Therapeutic procedure Unlikely
Item
patients must have pathologically documented acute myelogenous leukemia and either not be a candidate for myelosuppressive chemotherapy due to age or comorbid disease; or have relapsed acute myelogenous leukemia or be refractory to standard therapy and not likely to require cytoreductive therapy within 30 days.
boolean
C0023467 (UMLS CUI [1])
C1513793 (UMLS CUI [2,1])
C0392920 (UMLS CUI [2,2])
C0001779 (UMLS CUI [3])
C0009488 (UMLS CUI [4])
C0023467 (UMLS CUI [5,1])
C0035020 (UMLS CUI [5,2])
C2936643 (UMLS CUI [6,1])
C0205269 (UMLS CUI [6,2])
C0864494 (UMLS CUI [7,1])
C0087111 (UMLS CUI [7,2])
C0750558 (UMLS CUI [7,3])
ECOG performance status
Item
ecog performance status 0, 1 or 2
boolean
C1520224 (UMLS CUI [1])
Age
Item
age > 18 years
boolean
C0001779 (UMLS CUI [1])
Renal function | Liver function
Item
adequate kidney and hepatic function
boolean
C0232804 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
Chemotherapy | Therapeutic radiology procedure | Immunotherapy | Steroid therapy Systemic | hydroxyurea
Item
greater than 4 weeks from any chemotherapy, radiotherapy, immunotherapy, or systemic steroid therapy with the exception of hydroxyurea.
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2])
C0021083 (UMLS CUI [3])
C0149783 (UMLS CUI [4,1])
C0205373 (UMLS CUI [4,2])
C0020402 (UMLS CUI [5])
Bone Marrow Transplantation | Peripheral Stem Cell Transplantation | Donor Lymphocyte Infusion
Item
greater than 2 months following bone marrow or peripheral blood stem cell transplantation or donor lymphocyte infusion.
boolean
C0005961 (UMLS CUI [1])
C0242602 (UMLS CUI [2])
C1512034 (UMLS CUI [3])
Communicable Disease Uncontrolled
Item
uncontrolled active infection
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Cytoreductive Chemotherapy Patient need for Urgent | Cytoreductive surgery Patient need for Urgent | Cytoreductive Therapeutic radiology procedure Patient need for Urgent
Item
urgent need for cytoreductive chemotherapy, surgery, or radiotherapy
boolean
C0864494 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0686904 (UMLS CUI [1,3])
C0439609 (UMLS CUI [1,4])
C1112438 (UMLS CUI [2,1])
C0686904 (UMLS CUI [2,2])
C0439609 (UMLS CUI [2,3])
C0864494 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
C0686904 (UMLS CUI [3,3])
C0439609 (UMLS CUI [3,4])
Chemotherapy
Item
current chemotherapy or chemotherapy within the last 4 weeks.
boolean
C0392920 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnancy or nursing mothers
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
HIV Infection
Item
infection with hiv
boolean
C0019693 (UMLS CUI [1])