colorectal cancer
Item
1) histological diagnosis of colorectal cancer.
boolean
C0009402 (UMLS CUI [1])
age
Item
2） age: 18 - 75 years.
text
C0001779 (UMLS CUI [1])
prior chemotherapy
Item
3） no prior chemotherapy
text
C1514457 (UMLS CUI [1])
ecog
Item
4） ecog performance status 0 to 2
text
C1520224 (UMLS CUI [1])
life expectancy
Item
5) a life expectancy of at least 3 months
text
C0023671 (UMLS CUI [1])
organ function, hematologic, hepatic, renal function
Item
6) adequate function of major organs (bone marrow, heart, lungs, liver etc.). wbc ≧3,500/mm3 and neutrophil ≧2,000/mm3. hb ≧10.0 g/dl. platelet count ≧100,000/mm3. ast and alt ≦2.5 times the upper limit of normal (excluding liver metastasis). t-bil ≦1.5 mg/dl. creatinine ≦1.5 mg/ dl.
text
C0678852 (UMLS CUI [1])
C0221130 (UMLS CUI [2,1])
C0023508 (UMLS CUI [2,2])
C0948762 (UMLS CUI [2,3])
C0019046 (UMLS CUI [2,4])
C0005821 (UMLS CUI [2,5])
C0232741 (UMLS CUI [3,1])
C1278039 (UMLS CUI [3,2])
C0201899 (UMLS CUI [3,3])
C0201836 (UMLS CUI [3,4])
C0232804 (UMLS CUI [4,1])
C0201976 (UMLS CUI [4,2])
informed consent
Item
7) patients must have the ability to understand and the willingness to sign a written informed contact document.
boolean
C0021430 (UMLS CUI [1])
blood products, granulocyte colony stimulating factor
Item
1. patients receiving blood transfusion, blood derivatives or granulocyte-colony stimulating factor within 7days prior to entering the study.
boolean
C0456388 (UMLS CUI [1])
C0079459 (UMLS CUI [2])
oral intake
Item
2. patients can not have oral intake
boolean
C0518037 (UMLS CUI [1])
flucytosine
Item
3. patients receiving flucytosine treatment
boolean
C0016278 (UMLS CUI [1])
pleural effusion, ascites
Item
4. patients with severe pleural effusion or ascites.
boolean
C0032227 (UMLS CUI [1])
C0003962 (UMLS CUI [2])
brain metastasis
Item
5. patients who have brown brain metastasis
boolean
C0220650 (UMLS CUI [1])
diarrhea
Item
6. patients with diarrhea 4 or more times per day
boolean
C0011991 (UMLS CUI [1])
gastrointestinal bleeding
Item
7. patients with active gastrointestinal bleeding.
boolean
C0017181 (UMLS CUI [1])
intestinal obstruction
Item
8. patients with intestinal obstruction
boolean
C0021843 (UMLS CUI [1])
active infection
Item
9. patients with active infection.
boolean
C0009450 (UMLS CUI [1])
pulmonary disease
Item
10. patients with serious pulmonary disease (such as interstitial pneumonia, pulmonary fibrosis, pulmonary emphysema)
boolean
C0024115 (UMLS CUI [1])
serious complications
Item
11. patients with serious complications (such as intestinal paralysis, intestinal obstruction, interstitial pneumonia or pulmonary fibrosis, uncontrolled diabetes mellitus, heart failure, renal failure, or hepatic failure).
boolean
C0009566 (UMLS CUI [1])
cardiac disease
Item
12. patients with significant cardiac disease.
boolean
C0018799 (UMLS CUI [1])
multiple cancer
Item
13. patients with active multiple cancer.
boolean
C0346429 (UMLS CUI [1])
neuropathy
Item
14. patients with neuropathy ≥ grade 2
boolean
C0442874 (UMLS CUI [1])
pregnancy, childbearing potential, breast feeding
Item
15. patients who are pregnant, are of childbearing potential, or breast-feeding.
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2])
C0006147 (UMLS CUI [3])
mental disorder
Item
16. patients with severe mental disorder.
boolean
C0004936 (UMLS CUI [1])
allergic reaction
Item
17. patients with a history of serious allergic reaction.
boolean
C1527304 (UMLS CUI [1])
ineligibility by investigation
Item
18. judged to be ineligible for this protocol by the investigation.
boolean
C0220825 (UMLS CUI [1,1])
C1512714 (UMLS CUI [1,2])