Multiple Sclerosis Subtype disease length
Item
any disease sub-type of ms of at least two years duration
boolean
C0026769 (UMLS CUI [1,1])
C0872379 (UMLS CUI [1,2])
C0872146 (UMLS CUI [1,3])
Neuropathic pain Central Disease length
Item
central neuropathic pain (cnp) of at least three months and expected to remain stable for the study duration
boolean
C3714625 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0872146 (UMLS CUI [1,3])
Neuropathic pain Central Moderate Numeric Pain Scale
Item
moderate cnp defined by nrs pain score at baseline sum to at least 24
boolean
C3714625 (UMLS CUI [1,1])
C0205099 (UMLS CUI [1,2])
C0205081 (UMLS CUI [1,3])
C1518471 (UMLS CUI [1,4])
Analgesic therapy Neuropathic pain Central | Analgesic therapy Previous failed
Item
subject established on or previously tried and failed analgesic therapy for cnp
boolean
C0412784 (UMLS CUI [1,1])
C3714625 (UMLS CUI [1,2])
C0205099 (UMLS CUI [1,3])
C0412784 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
C0231175 (UMLS CUI [2,3])
Pharmaceutical Preparations Disease Modification | Pharmaceutical Preparations Dose Stable
Item
if receiving disease modifying medications, stable dose for 3 months and maintained for study duration
boolean
C0013227 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
C0013227 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
Nociceptive Pain | Musculoskeletal Pain | Spasm | Peripheral neuropathic pain | Somatoform pain disorder | Pain Due to Trigeminal Neuralgia
Item
subjects whose identified pain is likely to be nociceptive, musculoskeletal (including spasms) peripheral neuropathic or psychogenic in origin, or due to trigeminal neuralgia.
boolean
C3178766 (UMLS CUI [1])
C0026858 (UMLS CUI [2])
C0037763 (UMLS CUI [3])
C0458960 (UMLS CUI [4])
C0152174 (UMLS CUI [5])
C0030193 (UMLS CUI [6,1])
C0678226 (UMLS CUI [6,2])
C0040997 (UMLS CUI [6,3])
Neuropathic pain Severe | Neuropathic pain Interferes with Assessment Neuropathic pain central
Item
other non central neuropathic pain of a severity which is likely to interfere with the patients assessment of cnp
boolean
C3714625 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C3714625 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C1516048 (UMLS CUI [2,3])
C3714625 (UMLS CUI [2,4])
C0205099 (UMLS CUI [2,5])
Relapsing-remitting course Probably
Item
medical history suggests subject is likely to relapse/remit during course of study
boolean
C3808177 (UMLS CUI [1,1])
C0750492 (UMLS CUI [1,2])
Schizophrenia | FH: Schizophrenia | Psychotic Disorder | Personality Disorder Severe | Mental disorders | Depressive disorder Associated with Multiple Sclerosis
Item
history of schizophrenia (including family history), other psychotic illness, severe personality disorder or other significant psychiatric disorder other than depression associated with ms
boolean
C0036341 (UMLS CUI [1])
C0455382 (UMLS CUI [2])
C0033975 (UMLS CUI [3])
C0031212 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
C0004936 (UMLS CUI [5])
C0011581 (UMLS CUI [6,1])
C0332281 (UMLS CUI [6,2])
C0026769 (UMLS CUI [6,3])
Alcohol abuse | Epilepsy | Recurrent seizures | Hypersensitivity Cannabinoids
Item
known or suspected history of alcohol abuse, epilepsy or recurrent seizures or hypersensitivity to cannabinoids
boolean
C0085762 (UMLS CUI [1])
C0014544 (UMLS CUI [2])
C0748607 (UMLS CUI [3])
C0020517 (UMLS CUI [4,1])
C0006864 (UMLS CUI [4,2])
Travel Planned
Item
travel outside of the country of residence planned during the study
boolean
C0040802 (UMLS CUI [1,1])
C1301732 (UMLS CUI [1,2])
Heart failure | Renal Insufficiency | Hepatic impairment
Item
significant cardiac, renal or hepatic impairment
boolean
C0018801 (UMLS CUI [1])
C1565489 (UMLS CUI [2])
C0948807 (UMLS CUI [3])
Marihuana Recreational | Medical Marijuana | Pharmaceutical Preparations Cannabinoids Based | Drug Abstinence Unwilling
Item
subjects with current recreational cannabis, medicinal cannabis or synthetic cannabinoid based medications within 3 months prior to study entry and unwilling to abstain for the duration of the study
boolean
C0024808 (UMLS CUI [1,1])
C0242508 (UMLS CUI [1,2])
C0813973 (UMLS CUI [2])
C0013227 (UMLS CUI [3,1])
C0006864 (UMLS CUI [3,2])
C1705938 (UMLS CUI [3,3])
C0237443 (UMLS CUI [4,1])
C0558080 (UMLS CUI [4,2])