age, hypertension
Item
male and female patients age greater than or equal to 18 years with mild to moderate hypertension.
boolean
C0001779 (UMLS CUI [1])
C0020538 (UMLS CUI [2])
blood pressure, pre treatment
Item
pre-treated patients with normal or elevated blood pressure (bp) are eligible to participate if their pre-treatment medication can be withdrawn. at the end of the placebo run-in period sitting systolic bp greater than or equal to 140 and less than 180 mmhg and/or sitting diastolic bp greater than or equal to 90 and less than 110 mmhg at trough.
boolean
C0005823 (UMLS CUI [1,1])
C2709094 (UMLS CUI [1,2])
pregnancy, breast feeding, contraception
Item
female patients of childbearing potential must not be pregnant or lactating and must be using adequate contraception.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0700589 (UMLS CUI [3])
cardiovascular, renal, pulmonary, hepatic, gastrointestinal, endocrine, metabolic, hematological, oncological, neurological, neurological or psychiatric comorbidities
Item
patients with serious disorders which may limit the ability to evaluate the efficacy or safety of the test drug(s), including cardiovascular, renal, pulmonary, hepatic, gastrointestinal, endocrine/metabolic, haematological/oncological, neurological and psychiatric diseases.
boolean
C0009488 (UMLS CUI [1])
C0007222 (UMLS CUI [2])
C0022658 (UMLS CUI [3])
C0024115 (UMLS CUI [4])
C0023895 (UMLS CUI [5])
C0017178 (UMLS CUI [6])
C0014130 (UMLS CUI [7])
C0025517 (UMLS CUI [8])
C0018939 (UMLS CUI [9])
C0027651 (UMLS CUI [10])
C0027765 (UMLS CUI [11])
C0004936 (UMLS CUI [12])
myocardial infarction, unstable angina pectoris, percutaneous coronary intervention, heart failure, cerebrovascular accident, transient ischemic attack
Item
patients within the last 6 months having a history of myocardial infarction, unstable angina pectoris, percutaneous coronary intervention, heart failure, cerebrovascular accident, or transient ischemic attack.
boolean
C0027051 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C1532338 (UMLS CUI [3])
C0018801 (UMLS CUI [4])
C0038454 (UMLS CUI [5])
C0007787 (UMLS CUI [6])
laboratory values
Item
patients with clinically significant elevations in laboratory values at screening visit.
boolean
C0022885 (UMLS CUI [1])
secondary hypertension
Item
patients with secondary hypertension of any etiology, such as renal disease, pheochromocytoma, or cushing's syndrome.
boolean
C0155616 (UMLS CUI [1])
contraindications for olmesartan medoxomil, hydrochlorothiazide or amlodipine besylate
Item
patients with contraindications for olmesartan medoxomil, hydrochlorothiazide, and/or amlodipine besylate.
boolean
C1301624 (UMLS CUI [1,1])
C0386393 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0020261 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C0051696 (UMLS CUI [3,2])