Feeling depressed | Major Depressive Disorder | Dysthymic Disorder | Depressive disorder
Item
currently depressed (dsm-iv major depression, dysthymia or depression nos)
boolean
C0497307 (UMLS CUI [1])
C1269683 (UMLS CUI [2])
C0013415 (UMLS CUI [3])
C0011581 (UMLS CUI [4])
Hamilton rating scale for depression
Item
hamd-d (21-item) > 9
boolean
C0451203 (UMLS CUI [1])
Clinical Trial Investigational New Drugs ineffective | Escitalopram | Bupropion | Citalopram
Item
prior ineffective adequate trial on either study medication ($ 4 weeks on either escitalopram >20 mg/d or bupropion >300 mg/d; >4 weeks on citalopram >40 mg/d)
boolean
C0008976 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C3242229 (UMLS CUI [1,3])
C1099456 (UMLS CUI [2])
C0085208 (UMLS CUI [3])
C0008845 (UMLS CUI [4])
Seizures Risk Increased | Seizures Adult | Epilepsy | Pharmaceutical Preparations Seizures Risk Increased | Craniocerebral Trauma | Bulimia | Anorexia
Item
history suggesting increased risk for seizures (e.g., prior seizure as an adult, diagnosed seizure disorder, taking medication known to increase seizure risk, history of significant head trauma, history of bulimia or anorexia)
boolean
C0036572 (UMLS CUI [1,1])
C0035647 (UMLS CUI [1,2])
C0205217 (UMLS CUI [1,3])
C0036572 (UMLS CUI [2,1])
C0001675 (UMLS CUI [2,2])
C0014544 (UMLS CUI [3])
C0013227 (UMLS CUI [4,1])
C0036572 (UMLS CUI [4,2])
C0035647 (UMLS CUI [4,3])
C0205217 (UMLS CUI [4,4])
C0018674 (UMLS CUI [5])
C0006370 (UMLS CUI [6])
C0003123 (UMLS CUI [7])
Intolerance to Investigational New Drugs | Side effects manageable
Item
history of intolerance to either study medication unless patient and m.d. agree side effect is probably manageable
boolean
C1744706 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0879626 (UMLS CUI [2,1])
C1446391 (UMLS CUI [2,2])
Substance Use Disorders | Substance Dependence
Item
alcohol and/or drug abuse/dependence during past year
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
Medical Problem Major Uncontrolled | hypertension untreated | Diabetes Mellitus untreated
Item
major medical problems that are not well controlled (e.g., untreated hypertension or diabetes)
boolean
C1254481 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0205318 (UMLS CUI [1,3])
C0745134 (UMLS CUI [2])
C0011849 (UMLS CUI [3,1])
C0332155 (UMLS CUI [3,2])
Bipolar I disorder | Bipolar II disorder
Item
bipolar i, bipolar ii
boolean
C0853193 (UMLS CUI [1])
C0236788 (UMLS CUI [2])
Psychotic Disorder
Item
history of psychosis, or current psychosis
boolean
C0033975 (UMLS CUI [1])
Antidepressive Agents | Mood Stabilizer | taking medication to help sleep occasional | Benzodiazepine Anxiety
Item
currently taking antidepressants or mood stabilizers, which is judged unwise to discontinue (occasional sleep medication or benzodiazepine for anxiety is allowed)
boolean
C0003289 (UMLS CUI [1])
C2917435 (UMLS CUI [2])
C2054158 (UMLS CUI [3,1])
C0521114 (UMLS CUI [3,2])
C4048284 (UMLS CUI [4,1])
C0003467 (UMLS CUI [4,2])
Feeling depressed Absent | Feeling depressed Absent Due to Therapeutic procedure
Item
not currently depressed (whether considered due to current treatment or not)
boolean
C0497307 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C0497307 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0678226 (UMLS CUI [2,3])
C0087111 (UMLS CUI [2,4])
At risk for suicide | Suicide attempt Evaluation
Item
active suicidal risk (history of suicide attempts will be evaluated on a case by case basis)
boolean
C0563664 (UMLS CUI [1])
C0038663 (UMLS CUI [2,1])
C1261322 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
pregnant or breast-feeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Premenopausal state Contraceptive methods Lacking
Item
premenopausal women not using known effective birth control
boolean
C0232969 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0332268 (UMLS CUI [1,3])