Adenocarcinoma of prostate
Item
histologically confirmed adenocarcinoma of the prostate, meeting the following criteria:
boolean
C0007112 (UMLS CUI [1])
Gleason Score
Item
gleason score ≤ 7 (patterns 3+4 or 4+3 or less are acceptable)
boolean
C0332326 (UMLS CUI [1])
Tumor confined within the prostate
Item
cancer prostate-confined only
boolean
C1276626 (UMLS CUI [1])
TRUS finding: tumor confined to one lobe
Item
cancer confined to one lobe as defined by transrectal ultrasound (trus) biopsy
boolean
C0373345 (UMLS CUI [1,1])
C1276487 (UMLS CUI [1,2])
PSA measurement
Item
serum prostate-specific antigen (psa) ≤ 15 ng/ml
boolean
C0201544 (UMLS CUI [1])
Prostate volume and size
Item
prostate volume ≤ 40 cc or ap length of prostate < 4 cm
boolean
C1441416 (UMLS CUI [1])
C1287816 (UMLS CUI [2])
Unilateral prostate adenocarcinoma
Item
unilateral prostate adenocarcinoma must be verified in stage 1 of this trial unless the patient has had multi-sequence mri and transperineal template biopsies outside of this trial in similar procedure protocols to this trial
boolean
C0007112 (UMLS CUI [1,1])
C0205092 (UMLS CUI [1,2])
Metastatic disease
Item
no evidence of metastatic disease
boolean
C0027627 (UMLS CUI [1])
Prostatic calcifications
Item
no intraprostatic calcifications ≥ 10 mm in size in cancer-positive side of prostate
boolean
C1868729 (UMLS CUI [1])
Patients characterisitics
Item
patient characteristics:
boolean
C0815172 (UMLS CUI [1])
Life expectancy
Item
life expectancy ≥ 5 years
boolean
C0023671 (UMLS CUI [1])
Hypersensitivity to latex
Item
no latex allergies
boolean
C0020517 (UMLS CUI [1,1])
C0023115 (UMLS CUI [1,2])
ASA score
Item
no american society of anesthesiology surgical risk score iii or iv
boolean
C1531480 (UMLS CUI [1])
Contraindication to MRI
Item
no contraindications to mri scanning (e.g., severe claustrophobia, permanent cardiac pacemaker, or metallic implant likely to contribute significant artefact to images)
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
Health Status: fit for general or regional anesthesia
Item
must be fit for general anesthesia or regional anesthesia as assessed by the consultant anesthetist
boolean
C0018759 (UMLS CUI [1,1])
C0002915 (UMLS CUI [1,2])
C0018759 (UMLS CUI [2,1])
C0002911 (UMLS CUI [2,2])
Prior concurrent therapy
Item
prior concurrent therapy:
boolean
C0009429 (UMLS CUI [1])
Prior antiandrogen therapy
Item
more than 6 months since prior androgen suppression therapy
boolean
C0279492 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
Prior radiotherapy for prostate cancer
Item
no prior radiotherapy for prostate cancer
boolean
C0279134 (UMLS CUI [1,1])
C0600139 (UMLS CUI [1,2])
Prior chemotherapy for prostate cancer
Item
no prior chemotherapy for prostate cancer
boolean
C1514457 (UMLS CUI [1,1])
C0600139 (UMLS CUI [1,2])
Prior rectal surgery
Item
no prior significant rectal surgery preventing insertion of transrectal probe
boolean
C2066000 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
Prior transurethral resection or laser prostatectomy
Item
no prior transurethral resection of the prostate or laser prostatectomy
boolean
C0040771 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0860124 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
Prior high-intensity focused ultrasound, cryosurgery, thermal, or microwave therapy to the prostate
Item
no prior high-intensity focused ultrasound, cryosurgery, thermal, or microwave therapy to the prostate
boolean
C0205156 (UMLS CUI [1,1])
C0441583 (UMLS CUI [1,2])
C0205156 (UMLS CUI [2,1])
C0010408 (UMLS CUI [2,2])
C0205156 (UMLS CUI [3,1])
C0454527 (UMLS CUI [3,2])
C0438673 (UMLS CUI [4,1])
C0205156 (UMLS CUI [4,2])