Non-small-cell lung cancer
Item
histologically- or cytologically- confirmed non-small-cell lung cancer
boolean
C0007131 (UMLS CUI [1])
Tumor Stage
Item
stage iiib/iv
boolean
C1300072 (UMLS CUI [1])
Prior chemotherapy
Item
no prior chemotherapy
boolean
C1514457 (UMLS CUI [1])
Measurable disease
Item
presence of two-dimensional measurable disease. the measurable disease should not have been irradiated.
boolean
C1513041 (UMLS CUI [1])
CNS Metastases
Item
absence or irradiated and stable central nervous system metastatic disease
boolean
C0686377 (UMLS CUI [1])
Life expectancy
Item
life expectancy of more than 3 months
boolean
C0023671 (UMLS CUI [1])
Age
Item
age ≥ 70 years.
boolean
C0001779 (UMLS CUI [1])
Performance Stataus
Item
performance status (who) < 3
boolean
C1518965 (UMLS CUI [1])
Geriatric Assessment
Item
patients "non-frail" according to comprehensive geriatric assessment
boolean
C0017463 (UMLS CUI [1])
Absoulute neutrophil count, platelets, hemoglobin
Item
adequate bone marrow function (absolute neutrophil count > 1000/mm^3, platelet count > 100000/mm^3, hemoglobin > 9gr/mm^3).
boolean
C0948762 (UMLS CUI [1])
C0005821 (UMLS CUI [2])
C0019046 (UMLS CUI [3])
Bilirubin, SGOT, SGPT, Creatinine
Item
adequate liver (bilirubin < 1.5 times upper limit of normal and sgot/sgpt < 2 times upper limit of normal) and renal function (creatinine < 2mg/dl).
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201976 (UMLS CUI [4])
Left ventricular ejection fraction
Item
adequate cardiac function (lvef > 50%).
boolean
C0428772 (UMLS CUI [1])
Informed consent
Item
informed consent.
boolean
C0021430 (UMLS CUI [1])
Compliance
Item
psychiatric illness or social situation that would preclude study compliance.
boolean
C1321605 (UMLS CUI [1])
Comorbidity
Item
other concurrent uncontrolled illness.
boolean
C0009488 (UMLS CUI [1])
Prior malignancy
Item
other invasive malignancy within the past 5 years except nonmelanoma skin cancer.
boolean
C2735088 (UMLS CUI [1])
Caregiver
Item
no presence of a reliable care giver
boolean
C0085537 (UMLS CUI [1])
Experimental drugs
Item
other concurrent investigational agents.
boolean
C0304229 (UMLS CUI [1])