age, resident
Item
all men over 50 to 80 and all women 55 to 80 who are resident in kalaleh, golestan, for at least one year.
boolean
C0001779 (UMLS CUI [1])
C2347958 (UMLS CUI [2])
cardiovascular disease
Item
existing cardiovascular disease (stroke, transient ischaemic attack, myocardial infarction or angina)
boolean
C0007222 (UMLS CUI [1])
antihypertensive drugs, aspirin, statins
Item
already taking antihypertensive drugs, aspirin or statins
boolean
C0003364 (UMLS CUI [1])
C0004057 (UMLS CUI [2])
C0360714 (UMLS CUI [3])
indication for antihypertensive drug, aspirin or statins
Item
already have clinical indications for treatment with antihypertensive drugs, aspirin or statins.
boolean
C0003364 (UMLS CUI [1,1])
C1444656 (UMLS CUI [1,2])
C0004057 (UMLS CUI [2,1])
C1444656 (UMLS CUI [2,2])
C0360714 (UMLS CUI [3,1])
C1444656 (UMLS CUI [3,2])
blood pressure
Item
blood pressure >160/100 mm hg
boolean
C0005823 (UMLS CUI [1])
total cholesterol
Item
total cholesterol > 240 mg/dl (or ldl >190 mg/dl)
boolean
C1445957 (UMLS CUI [1])
hba1c
Item
probable diabetes: hba1c >6.0
boolean
C0019018 (UMLS CUI [1])
polypill contraindication
Item
contraindication to a component of the polypill
boolean
C0013227 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
aspirin contraindication
Item
contraindications to aspirin
boolean
C0004057 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
aspirin allergy
Item
previous history of allergy to aspirin
boolean
C0004058 (UMLS CUI [1])
peptic ulcer (bleeding)
Item
history of peptic ulcer bleeding in whole life or endoscopic evidence of peptic ulcer within the past 3 months
boolean
C0030920 (UMLS CUI [1])
C0030922 (UMLS CUI [2])
statin contraindication
Item
contraindications to statins
boolean
C0360714 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
liver failure contraindication to blood pressure lowering
Item
liver failure contraindications to further blood pressure lowering
boolean
C0085605 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
C0003364 (UMLS CUI [1,3])
systolic blood pressure, diastolic blood pressure
Item
systolic blood pressure ≤90 mm hg or diastolic blood pressure ≤70 mm hg
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
symptomatic orthostatic hypotension
Item
symptomatic postural hypotension
boolean
C0740482 (UMLS CUI [1])
difference between mean seated blood pressure and standing blood pressure
Item
difference between mean seated bp and standing bp greater than 20 mm hg
boolean
C0428886 (UMLS CUI [1,1])
C0277814 (UMLS CUI [1,2])
C0428886 (UMLS CUI [2,1])
C0231472 (UMLS CUI [2,2])
thiazide contraindication
Item
contraindications to thiazide
boolean
C0541746 (UMLS CUI [1,1])
C0522473 (UMLS CUI [1,2])
uric acid, gout
Item
uric acid >8 for men and uric acid >6 for women / gout (~10%)
boolean
C0041980 (UMLS CUI [1])
C0018099 (UMLS CUI [2])
creatinine
Item
creatinine >1.2 mg/dl
boolean
C0201976 (UMLS CUI [1])
comorbidities limiting compliance
Item
other predominant medical problem that may limit compliance with study treatment including:
boolean
C0009488 (UMLS CUI [1,1])
C1321605 (UMLS CUI [1,2])
C0439801 (UMLS CUI [1,3])
alcohol abuse
Item
history of alcohol abuse: more than 60cc for women and more than 80cc for men
boolean
C0085762 (UMLS CUI [1])
drug abuse
Item
history of drug abuse: iv drug abuser or eating or smoking more than 4 times a week
boolean
C0013146 (UMLS CUI [1])
psychiatric illness
Item
limiting psychiatric illness (eg: mania, schizophrenia, severe depression, psychosis or dementia)
boolean
C0004936 (UMLS CUI [1])
walking ability
Item
limiting physical disability sufficient to prevent subject from walking
boolean
C0559964 (UMLS CUI [1])
life-threatening condition
Item
other life-threatening condition such as cancer
boolean
C2826244 (UMLS CUI [1,1])
C0012634 (UMLS CUI [1,2])