Age
Item
patient is male or female and = 18 years of age
boolean
C0001779 (UMLS CUI [1])
Essential Hypertension | Antihypertensive Agents | Blood Pressure goal failed
Item
patients with essential hypertension previously treated with antihypertensive medications for at least 4 weeks but did not reach the blood pressure goal
boolean
C0085580 (UMLS CUI [1])
C0003364 (UMLS CUI [2])
C0005823 (UMLS CUI [3,1])
C0018017 (UMLS CUI [3,2])
C0231175 (UMLS CUI [3,3])
Condition Interferes with Research results | Therapeutic procedure Interferes with Research results | Laboratory test abnormality Interferes with Research results | Circumstance Interferes with Research results | Condition Interferes with Study Subject Participation Status | Therapeutic procedure Interferes with Study Subject Participation Status | Laboratory test abnormality Interferes with Study Subject Participation Status | Circumstance Interferes with Study Subject Participation Status
Item
history of any condition, therapy, lab abnormality or other circumstance that might confound the results of the study, or interfere with the patient's participation for the full duration of the study, such that it is not in the best interest of the patient/subject to participate
boolean
C0348080 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0683954 (UMLS CUI [1,3])
C0087111 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0683954 (UMLS CUI [2,3])
C0438215 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0683954 (UMLS CUI [3,3])
C0680082 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0683954 (UMLS CUI [4,3])
C0348080 (UMLS CUI [5,1])
C0521102 (UMLS CUI [5,2])
C2348568 (UMLS CUI [5,3])
C0087111 (UMLS CUI [6,1])
C0521102 (UMLS CUI [6,2])
C2348568 (UMLS CUI [6,3])
C0438215 (UMLS CUI [7,1])
C0521102 (UMLS CUI [7,2])
C2348568 (UMLS CUI [7,3])
C0680082 (UMLS CUI [8,1])
C0521102 (UMLS CUI [8,2])
C2348568 (UMLS CUI [8,3])
Pregnancy | Breast Feeding | Pregnancy Expected
Item
pregnant or breastfeeding, or expecting to conceive within the projected duration of the study
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032961 (UMLS CUI [3,1])
C1517001 (UMLS CUI [3,2])
Essential Hypertension Severe
Item
previous history of severe essential hypertension
boolean
C0085580 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
Cerebrovascular accident | Myocardial Infarction
Item
history of stroke or myocardial infarction (heart attack)
boolean
C0038454 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
Kidney Disease Evidence of | Liver disease Evidence of
Item
evidence of renal or liver disease
boolean
C0022658 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0023895 (UMLS CUI [2,1])
C0332120 (UMLS CUI [2,2])
Diabetic - poor control
Item
uncontrolled diabetes mellitus
boolean
C0421258 (UMLS CUI [1])
Blood Coagulation Disorder
Item
any known bleeding disorder
boolean
C0005779 (UMLS CUI [1])
Hypersensitivity Investigational New Drugs | intolerance to Investigational New Drugs | Losartan allergy | intolerance to Losartan | Hydrochlorothiazide allergy | intolerance to Hydrochlorothiazide
Item
known sensitivity or intolerance to the study medication (losartan or hydrochlorothiazide)
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C1744706 (UMLS CUI [2,1])
C0013230 (UMLS CUI [2,2])
C0571952 (UMLS CUI [3])
C1744706 (UMLS CUI [4,1])
C0126174 (UMLS CUI [4,2])
C0571898 (UMLS CUI [5])
C1744706 (UMLS CUI [6,1])
C0020261 (UMLS CUI [6,2])
Antihypertensive Agents | Pharmaceutical Preparations Affecting Blood Pressure
Item
other antihypertensive medications or medications that may affect blood pressure
boolean
C0003364 (UMLS CUI [1])
C0013227 (UMLS CUI [2,1])
C0392760 (UMLS CUI [2,2])
C0005823 (UMLS CUI [2,3])