Age
Item
volunteers will be aged 18-75 years.
boolean
C0001779 (UMLS CUI [1])
Hypertensive disease
Item
hypertension- either
boolean
C0020538 (UMLS CUI [1])
Hypertensive disease untreated | Blood Pressure
Item
untreated, bp 140-170/90-110
boolean
C0020538 (UMLS CUI [1,1])
C0332155 (UMLS CUI [1,2])
C0005823 (UMLS CUI [2])
Hypertensive disease Treated | Adrenergic beta-1 Receptor Antagonists | Diuretics | Blood Pressure
Item
treated for over 1 month with drugs other than beta blockers or diuretic and bp>140/85
boolean
C0020538 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0304516 (UMLS CUI [2])
C0012798 (UMLS CUI [3])
C0005823 (UMLS CUI [4])
Hypertensive disease Treated | Adrenergic beta-1 Receptor Antagonists | Diuretics | Blood Pressure | Change of medication Willing
Item
treated for over 1 month with drugs other than beta blockers or diuretic and bp<140/85 and patient willing to change medication for eight months.
boolean
C0020538 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0304516 (UMLS CUI [2])
C0012798 (UMLS CUI [3])
C0005823 (UMLS CUI [4])
C0580105 (UMLS CUI [5,1])
C0600109 (UMLS CUI [5,2])
Thiazide Diuretics | Adrenergic beta-1 Receptor Antagonists | Pharmaceutical Preparations Alternative | control of blood pressure Improvement Unsuccessful
Item
any patient already taking thiazide diuretics or beta blockers in whom these drugs cannot be switched to alternative drugs with similar or better blood pressure control.
boolean
C0012802 (UMLS CUI [1])
C0304516 (UMLS CUI [2])
C0013227 (UMLS CUI [3,1])
C1523987 (UMLS CUI [3,2])
C1753303 (UMLS CUI [4,1])
C2986411 (UMLS CUI [4,2])
C1272705 (UMLS CUI [4,3])
Intolerance to Pharmaceutical Preparations
Item
any patient who is intolerant of these medications will be excluded from the study.
boolean
C1744706 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
Gout | Asthma | Medical contraindication Investigational New Drugs
Item
patients with gout, asthma or any other contraindications to the study drugs will be excluded.
boolean
C0018099 (UMLS CUI [1])
C0004096 (UMLS CUI [2])
C1301624 (UMLS CUI [3,1])
C0013230 (UMLS CUI [3,2])
Childbearing Potential Contraceptive methods Missing
Item
women of child bearing age not using contraception.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C1705492 (UMLS CUI [1,3])
Heart failure | Liver Failure | Kidney Failure | Terminal illness | Malignant Neoplasms
Item
volunteers with heart failure, liver failure, renal failure, terminal illnesses (e.g. cancer)
boolean
C0018801 (UMLS CUI [1])
C0085605 (UMLS CUI [2])
C0035078 (UMLS CUI [3])
C0679247 (UMLS CUI [4])
C0006826 (UMLS CUI [5])
Informed Consent Unable
Item
volunteers not able to give informed consent
boolean
C0021430 (UMLS CUI [1,1])
C1299582 (UMLS CUI [1,2])
Diabetes Mellitus
Item
patients with diabetes
boolean
C0011849 (UMLS CUI [1])