Outpatients | Age
Item
outpatients 18 years of age and older.
boolean
C0029921 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Blood Pressure criteria
Item
patients must meet following blood pressure criteria:
boolean
C0005823 (UMLS CUI [1,1])
C0243161 (UMLS CUI [1,2])
Sitting diastolic blood pressure mean | Sphygmomanometers Blood pressure ambulatory | Diastolic blood pressure Ambulatory mean Duration
Item
at visit 2 : office mean sitting diastolic blood pressure ≥ 90 mmhg and < 110 mmhg at visit 3 : office mean sitting diastolic blood pressure ≥ 95 mmhg and < 110 mmhg before application of ambulatory blood pressure measurement device at visit 3 : 24-hr mean ambulatory diastolic blood pressure ≥ 85 mmhg
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C0183427 (UMLS CUI [2,1])
C0855316 (UMLS CUI [2,2])
C0428883 (UMLS CUI [3,1])
C0439841 (UMLS CUI [3,2])
C0444504 (UMLS CUI [3,3])
C0449238 (UMLS CUI [3,4])
Sitting diastolic blood pressure mean | Difference Absolute Quantity Visit Number
Item
patient must have an absolute difference of ≤ 10 mmhg in their office mean sitting diastolic blood pressure between visit 2 and 3.
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
C1705242 (UMLS CUI [2,1])
C0205344 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C1549755 (UMLS CUI [2,4])
Gender | Postmenopausal state | Female Sterilization | Gender Contraceptive methods | Contraceptives, Oral | Contraception, Barrier | Vaginal Spermicides | Intrauterine Devices
Item
male or female patients are eligible. female patients must be either post-menopausal for at least one year, surgically sterile or using effective contraceptive methods such as oral contraceptives, barrier method with spermicide or an intrauterine device. reliable contraception should be maintained throughout the study and for 7 days after study drug discontinuation.
boolean
C0079399 (UMLS CUI [1])
C0232970 (UMLS CUI [2])
C0015787 (UMLS CUI [3])
C0079399 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0009905 (UMLS CUI [5])
C0004764 (UMLS CUI [6])
C0087145 (UMLS CUI [7])
C0021900 (UMLS CUI [8])
Study Subject Participation Status | Informed Consent
Item
patients who are eligible and able to participate in the study, and who consent to do so after the purpose and nature of the investigation has been clearly explained to them (written informed consent).
boolean
C2348568 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
Hypertension, severe | Sitting diastolic blood pressure mean | Sitting systolic blood pressure mean
Item
severe hypertension [office mean sitting diastolic blood pressure ≥ 110 mmhg and/or office mean sitting systolic blood pressure (mssbp) ≥ 180 mmhg].
boolean
C4013784 (UMLS CUI [1])
C1319894 (UMLS CUI [2,1])
C0444504 (UMLS CUI [2,2])
C1319893 (UMLS CUI [3,1])
C0444504 (UMLS CUI [3,2])
Heart failure New York Heart Association Classification
Item
current diagnosis of heart failure (nyha class ii-iv).
boolean
C0018801 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Myocardial Infarction | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention
Item
history of myocardial infarction, coronary bypass surgery, or any percutaneous coronary intervention (pci) during the 12 months prior to visit 1.
boolean
C0027051 (UMLS CUI [1])
C0010055 (UMLS CUI [2])
C1532338 (UMLS CUI [3])
Medical contraindication Investigational New Drugs | Medical contraindication Suspected Investigational New Drugs | allergy to angiotensin converting enzyme inhibitor | Allergy to angiotensin II receptor antagonist
Item
known or suspected contraindications to the study medications, including history of allergy to ace-inhibitors or arbs.
boolean
C1301624 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
C0013230 (UMLS CUI [2,3])
C1319912 (UMLS CUI [3])
C2585204 (UMLS CUI [4])
Upper arm Circumference
Item
upper arm circumference > 42 cm.
boolean
C0446516 (UMLS CUI [1,1])
C0332520 (UMLS CUI [1,2])
Shift worker | Night shift worker
Item
third shift or night workers.
boolean
C0425104 (UMLS CUI [1])
C0555008 (UMLS CUI [2])
Clinical Trial Eligibility Criteria Study Protocol
Item
other protocol-defined inclusion/exclusion criteria may apply
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])