Diabetes Mellitus, Non-Insulin-Dependent
Item
type 2 diabetes.
boolean
C0011860 (UMLS CUI [1])
Glycosylated hemoglobin A
Item
hba1c (a measure of the average amount of sugar in blood over the last 2 or 3 months) levels are between 7.0 and 9.0.
boolean
C0019018 (UMLS CUI [1])
Metformin U/day | Antidiabetics Absent
Item
taking 850mg or more per day metformin, but not taking any other diabetes medications.
boolean
C0025598 (UMLS CUI [1,1])
C0456683 (UMLS CUI [1,2])
C0935929 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
Antidiabetics Discontinue Able | Antidiabetics Discontinue Willing
Item
must be medically able and willing to discontinue diabetic medications from at least 2 weeks prior to first study dose until the last study assessment.
boolean
C0935929 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C0085732 (UMLS CUI [1,3])
C0935929 (UMLS CUI [2,1])
C1444662 (UMLS CUI [2,2])
C0600109 (UMLS CUI [2,3])
Antidiabetics Absent | Diabetes mellitus under control Diet | Glucohemoglobin measurement
Item
diabetic subjects who have not yet started taking diabetes medications or whose diabetes is controlled by diet alone may also be eligible to enroll if their hba1c is within 7.5 to 9.0.
boolean
C0935929 (UMLS CUI [1,1])
C0332197 (UMLS CUI [1,2])
C2062378 (UMLS CUI [2,1])
C0011878 (UMLS CUI [2,2])
C0202054 (UMLS CUI [3])
Postmenopausal state | Female Sterilization
Item
women may be eligible if they are post-menopausal or surgically sterile.
boolean
C0232970 (UMLS CUI [1])
C0015787 (UMLS CUI [2])
Angiotensin-Converting Enzyme Inhibitors Dose Stable | Adrenergic beta-1 Receptor Antagonists Dose Stable | Calcium Channel Blockers Dose Stable | Hydroxymethylglutaryl-CoA Reductase Inhibitors Dose Stable
Item
if taking ace inhibitors, beta-blockers, calcium channel blockers, or statin type drugs, you may be eligible if your dose has been stable for at least 30 days prior to the start of the clinical trial.
boolean
C0003015 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0304516 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
C0006684 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
C0205360 (UMLS CUI [3,3])
C0360714 (UMLS CUI [4,1])
C0178602 (UMLS CUI [4,2])
C0205360 (UMLS CUI [4,3])
Illicit drug use | Hepatitis B Antibodies | Hepatitis C Antibodies | HIV Antibodies
Item
using illicit drugs, or have antibodies to hepatitis b, hepatitis c, or hiv.
boolean
C0281875 (UMLS CUI [1])
C0019164 (UMLS CUI [2])
C0166049 (UMLS CUI [3])
C0019683 (UMLS CUI [4])
Health Problem Major | Diabetes Mellitus, Non-Insulin-Dependent
Item
have any major health problems other than type 2 diabetes.
boolean
C0018684 (UMLS CUI [1,1])
C0033213 (UMLS CUI [1,2])
C0205164 (UMLS CUI [1,3])
C0011860 (UMLS CUI [2])
Insulin regime Patient need for | Antidiabetics Oral Patient need for | Metformin
Item
require insulin therapy or oral antidiabetic medication other than metformin.
boolean
C0557978 (UMLS CUI [1,1])
C0686904 (UMLS CUI [1,2])
C0935929 (UMLS CUI [2,1])
C1527415 (UMLS CUI [2,2])
C0686904 (UMLS CUI [2,3])
C0025598 (UMLS CUI [3])
Urinary tract infection | Kidney Disease
Item
subjects who have had a urinary tract infection within 4 weeks of the start of the study or who have kidney disease.
boolean
C0042029 (UMLS CUI [1])
C0022658 (UMLS CUI [2])
Hypotension | Hypertensive disease
Item
subjects with either low or high blood pressure.
boolean
C0020649 (UMLS CUI [1])
C0020538 (UMLS CUI [2])
Gender Sexual Abstinence Unwilling | Gender Male condom Unwilling | Pregnancy | Breast Feeding | Gender Contraceptive methods Unwilling
Item
men who are unwilling to abstain from intercourse, or use a condom with a pregnant or nursing female, or who are unwilling to use a condom with another form of contraception with a female who could become pregnant.
boolean
C0079399 (UMLS CUI [1,1])
C0036899 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C0009653 (UMLS CUI [2,2])
C0558080 (UMLS CUI [2,3])
C0032961 (UMLS CUI [3])
C0006147 (UMLS CUI [4])
C0079399 (UMLS CUI [5,1])
C0700589 (UMLS CUI [5,2])
C0558080 (UMLS CUI [5,3])