Non-Insulin-Dependent Diabetes Mellitus Established diagnosis | Antidiabetics | Glycosylated hemoglobin A Percentage
Item
1. type 2 diabetes with medication for diabetes＞ 3 years (established diagnosis, hba1c<10% )
boolean
C0011860 (UMLS CUI [1,1])
C0332139 (UMLS CUI [1,2])
C0935929 (UMLS CUI [2])
C0019018 (UMLS CUI [3,1])
C0439165 (UMLS CUI [3,2])
Polyneuropathy Symptomatic | NEUROPATHY PERIPHERAL STOCKING GLOVE | Pain tingling
Item
2. symptomatic polyneuropathy (stocking distribution and tingling pain)
boolean
C0152025 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0746874 (UMLS CUI [2])
C0030193 (UMLS CUI [3,1])
C2242996 (UMLS CUI [3,2])
Foot pain Diabetic Neuropathy | Medication effects Stable | Medication effects Unsatisfactory
Item
3. stable but not satisfactory effects of drugs for diabetic neuropathic foot pain (stable effects of medication for over 6 months)
boolean
C0016512 (UMLS CUI [1,1])
C0011882 (UMLS CUI [1,2])
C1319171 (UMLS CUI [2,1])
C0205360 (UMLS CUI [2,2])
C1319171 (UMLS CUI [3,1])
C0439856 (UMLS CUI [3,2])
Appropriateness Polyneuropathy Nerve Conduction velocity criteria
Item
4. fitness of polyneuropathy on nerve conduction velocity (ncv) criteria
boolean
C0814634 (UMLS CUI [1,1])
C0152025 (UMLS CUI [1,2])
C0429381 (UMLS CUI [1,3])
C0243161 (UMLS CUI [1,4])
Informed Consent
Item
5. willing and able to give written informed consent.
boolean
C0021430 (UMLS CUI [1])
Protocol Compliance
Item
6. willing and able to complete the entire study course and comply with study directions.
boolean
C0525058 (UMLS CUI [1])
Unsuccessful injection Due to Limitation Physiological
Item
1. injection not possible due to physiologic barriers.
boolean
C0940893 (UMLS CUI [1,1])
C0678226 (UMLS CUI [1,2])
C0449295 (UMLS CUI [1,3])
C0205463 (UMLS CUI [1,4])
Pregnancy | Breast Feeding
Item
2. subject is pregnant or lactating.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Childbearing Potential Contraceptive methods Inadequate
Item
3. females of childbearing age who are not using a reliable method of avoiding pregnancy.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0205412 (UMLS CUI [1,3])
Disease Significant | Mental disorder Significant
Item
4. significant medical or psychiatric disease.
boolean
C0012634 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
Risk Increase Botox Exposure to
Item
5. any condition that may put the subject at increased risk with exposure to botox®, including
boolean
C0035647 (UMLS CUI [1,1])
C0442805 (UMLS CUI [1,2])
C0700702 (UMLS CUI [1,3])
C0332157 (UMLS CUI [1,4])
Myasthenia Gravis Interferes with neuromuscular function | Lambert-Eaton syndrome Interferes with neuromuscular function | Amyotrophic Lateral Sclerosis Interferes with neuromuscular function | Disease Interferes with neuromuscular function
Item
6. diagnosed myasthenia gravis, eaton-lambert syndrome, amyotrophic lateral sclerosis, or any other disease that might interfere with neuromuscular function.
boolean
C0026896 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0597053 (UMLS CUI [1,3])
C3161080 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0597053 (UMLS CUI [2,3])
C0002736 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0597053 (UMLS CUI [3,3])
C0012634 (UMLS CUI [4,1])
C0521102 (UMLS CUI [4,2])
C0597053 (UMLS CUI [4,3])
Aminoglycoside Antibiotics Interfere with neuromuscular function | Curare-like Agents Interfere with neuromuscular function | Pharmaceutical Preparations Interfere with neuromuscular function
Item
7. use of aminoglycoside antibiotics, curare-like agents, or other agents that might interfere with neuromuscular function.
boolean
C0003233 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0597053 (UMLS CUI [1,3])
C0010464 (UMLS CUI [2,1])
C0521102 (UMLS CUI [2,2])
C0597053 (UMLS CUI [2,3])
C0013227 (UMLS CUI [3,1])
C0521102 (UMLS CUI [3,2])
C0597053 (UMLS CUI [3,3])
Medication Overuse
Item
8. acute medication overuse in the investigator's best judgment.
boolean
C3266697 (UMLS CUI [1])
Substance Use Disorders
Item
9. alcohol or drug abuse.
boolean
C0038586 (UMLS CUI [1])
Heavy smoker
Item
10. heavy smokers
boolean
C0857118 (UMLS CUI [1])
Communicable Disease Injection site | Skin problem Injection site
Item
11. infection or skin problems at any of the injection sites.
boolean
C0009450 (UMLS CUI [1,1])
C2700396 (UMLS CUI [1,2])
C0281822 (UMLS CUI [2,1])
C2700396 (UMLS CUI [2,2])
Hypersensitivity Investigational New Drugs | Hypersensitivity Investigational New Drugs Constituents
Item
12. known allergy or sensitivity to the study medications or its components.
boolean
C0020517 (UMLS CUI [1,1])
C0013230 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0013230 (UMLS CUI [2,2])
C0729650 (UMLS CUI [2,3])
Anesthetics Injection Muscles Targeted | Steroids Injection Muscles Targeted
Item
13. injections of anesthetics or steroids into the study targeted muscles within one month prior to the day of injection
boolean
C0002932 (UMLS CUI [1,1])
C1828121 (UMLS CUI [1,2])
C0026845 (UMLS CUI [1,3])
C1521840 (UMLS CUI [1,4])
C0038317 (UMLS CUI [2,1])
C1828121 (UMLS CUI [2,2])
C0026845 (UMLS CUI [2,3])
C1521840 (UMLS CUI [2,4])
Study Subject Participation Status
Item
14. concurrent participation in another clinical trial within 30 days of the beginning of this study.
boolean
C2348568 (UMLS CUI [1])
Botulinum Toxin Type A | Botulinum toxin type B
Item
15. previous use of botulinum toxin. (types a or b)
boolean
C0006050 (UMLS CUI [1])
C0006051 (UMLS CUI [2])
Target Area Muscular Atrophy Profound | Target Area Muscle Weakness Excessive | Target Area Injection
Item
16. profound atrophy or excessive weakness of the muscles in the target area(s) or injection.
boolean
C1521840 (UMLS CUI [1,1])
C0205146 (UMLS CUI [1,2])
C0026846 (UMLS CUI [1,3])
C0439808 (UMLS CUI [1,4])
C1521840 (UMLS CUI [2,1])
C0205146 (UMLS CUI [2,2])
C0151786 (UMLS CUI [2,3])
C0442802 (UMLS CUI [2,4])
C1521840 (UMLS CUI [3,1])
C0205146 (UMLS CUI [3,2])
C1533685 (UMLS CUI [3,3])
Peripheral artery occlusion Evidence of
Item
17. evidence of peripheral artery occlusion
boolean
C1112655 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
Liver Dysfunction Evidence of | Renal Insufficiency Evidence of
Item
18. evidence of liver or renal function impairment
boolean
C0086565 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C1565489 (UMLS CUI [2,1])
C0332120 (UMLS CUI [2,2])
old stroke Evidence of
Item
19. evidence old stroke
boolean
C0850564 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])