Age | Pregnancy
Item
the patient (male or non-pregnant female) must be > 18 years of age.
boolean
C0001779 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
Informed Consent | Informed Consent Patient Representatives
Item
the patient or legally authorized representative must sign a written informed consent, prior to the procedure, using a form that is approved by the local institutional review board.
boolean
C0021430 (UMLS CUI [1])
C0021430 (UMLS CUI [2,1])
C0030701 (UMLS CUI [2,2])
Coronary Artery Disease angiography | Coronary artery Major Percent Diameter Stenosis Measurement
Item
angiographically documented coronary artery disease defined as the presence of at least one 50% or greater stenosis of a major coronary artery.
boolean
C1956346 (UMLS CUI [1,1])
C0002978 (UMLS CUI [1,2])
C0205042 (UMLS CUI [2,1])
C0205164 (UMLS CUI [2,2])
C3897965 (UMLS CUI [2,3])
Stabilization Post Acute Coronary Syndrome | Ischemic pain At rest | Congestive heart failure | Cardiac Arrhythmia Malignant
Item
stabilized post any prior acs event (i.e., without ongoing ischemic rest pain, congestive heart failure, or malignant arrhythmias) for at least 3 months
boolean
C1293130 (UMLS CUI [1,1])
C0687676 (UMLS CUI [1,2])
C0948089 (UMLS CUI [1,3])
C0745417 (UMLS CUI [2,1])
C0443144 (UMLS CUI [2,2])
C0018802 (UMLS CUI [3])
C0003811 (UMLS CUI [4,1])
C0205282 (UMLS CUI [4,2])
Fasting blood glucose measurement
Item
fasting blood glucose 87-125 mg/dl
boolean
C0428568 (UMLS CUI [1])
Age
Item
age <18 years
boolean
C0001779 (UMLS CUI [1])
Metformin allergy | Hypersensitivity rosiglitazone
Item
known hypersensitivity to metformin or rosiglitazone
boolean
C0571648 (UMLS CUI [1])
C0020517 (UMLS CUI [2,1])
C0289313 (UMLS CUI [2,2])
Renal Insufficiency | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
renal insufficiency defined as calculated creatinine clearance (crcl) <40 ml/min using the following formula:
boolean
C1565489 (UMLS CUI [1])
C2711451 (UMLS CUI [2])
Estimation of creatinine clearance by Cockcroft-Gault formula | Gender
Item
men: crcl (ml/min) = weight (kg) x (140-age) 72 x serum creatinine (mg/dl) women: 0.85 x the value calculated for men
boolean
C2711451 (UMLS CUI [1])
C0079399 (UMLS CUI [2])
Pregnancy | Breast Feeding | Childbearing Potential
Item
pregnant and/or lactating women, and women of child bearing potential are excluded from this trial
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3])
Comorbidity | Life Expectancy
Item
co-morbidity such that the patient is not expected to survive >2 years
boolean
C0009488 (UMLS CUI [1])
C0023671 (UMLS CUI [2])
rosiglitazone | Metformin
Item
current therapy with rosiglitazone or metformin
boolean
C0289313 (UMLS CUI [1])
C0025598 (UMLS CUI [2])
Percutaneous Coronary Intervention
Item
pci within the previous six months (other than for the qualifying event)
boolean
C1532338 (UMLS CUI [1])
Coronary Artery Bypass Surgery | Coronary Artery Bypass Surgery Scheduled | Coronary Artery Bypass Surgery Perform Decision
Item
prior cabg within the previous two months, scheduled cabg, or a decision to perform cabg made prior to enrollment
boolean
C0010055 (UMLS CUI [1])
C0010055 (UMLS CUI [2,1])
C0205539 (UMLS CUI [2,2])
C0010055 (UMLS CUI [3,1])
C0884358 (UMLS CUI [3,2])
C0679006 (UMLS CUI [3,3])
Diabetes Mellitus | Fasting blood glucose measurement | Antidiabetics
Item
overt diabetes mellitus (fbg>126 or antidiabetic therapy)
boolean
C0011849 (UMLS CUI [1])
C0428568 (UMLS CUI [2])
C0935929 (UMLS CUI [3])
Congestive heart failure
Item
any diagnosis of congestive heart failure
boolean
C0018802 (UMLS CUI [1])
Hepatobiliary disease Obstructive | Liver disease | Aspartate aminotransferase increased | Alanine aminotransferase increased | Gamma-glutamyl transferase raised | Elevated total bilirubin | Alkaline phosphatase raised | Myocardial Infarction Relationship Absent
Item
obstructive hepatobiliary disease or other significant hepatic disease (defined as the presence of at least one of the following: ast, alt, ggt, total bilirubin, or alkaline phosphatase >3x upper limit normal, not related to mi
boolean
C0267792 (UMLS CUI [1,1])
C0549186 (UMLS CUI [1,2])
C0023895 (UMLS CUI [2])
C0151904 (UMLS CUI [3])
C0151905 (UMLS CUI [4])
C0151662 (UMLS CUI [5])
C0741494 (UMLS CUI [6])
C0151849 (UMLS CUI [7])
C0027051 (UMLS CUI [8,1])
C0439849 (UMLS CUI [8,2])
C0332197 (UMLS CUI [8,3])
Study Subject Participation Status | Investigational New Drugs | product marketing
Item
participation in any other clinical trials involving investigational or marketed products within 30 days prior to entry in the study.
boolean
C2348568 (UMLS CUI [1])
C0013230 (UMLS CUI [2])
C0683746 (UMLS CUI [3])