Primary adenocarcinoma of colon | Adenocarcinoma of rectum Primary
Item
histological proof of adenocarcinoma in primary colon or rectum tumor.
boolean
C3472669 (UMLS CUI [1])
C0149978 (UMLS CUI [2,1])
C0205225 (UMLS CUI [2,2])
Colorectal cancer metastatic Evidence of | Neoplasm Recurrence, Local | Unresectable Malignant Neoplasm
Item
evidence of metastatic colorectal cancer or loco-regional recurrence or unresectable disease.
boolean
C0948380 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0027643 (UMLS CUI [2])
C1336869 (UMLS CUI [3])
Age
Item
ages 18 to 86 years.
boolean
C0001779 (UMLS CUI [1])
Measurable Disease 2-Dimensional Quantity | Measurable Disease Diameter Size Quantity
Item
presence of at least one bi-dimensionally measurable disease with at least one diameter > or = 2 cm.
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C1513041 (UMLS CUI [2,1])
C1301886 (UMLS CUI [2,2])
C0456389 (UMLS CUI [2,3])
C1265611 (UMLS CUI [2,4])
WHO performance status scale | ECOG performance status
Item
who/ecog performance status < 3 (0, 1, or 2)
boolean
C1298650 (UMLS CUI [1])
C1520224 (UMLS CUI [2])
oxaliplatin | Fluorouracil | Leucovorin
Item
prior treatment with oxaliplatin, 5-fu, or leucovorin permitted.
boolean
C0069717 (UMLS CUI [1])
C0016360 (UMLS CUI [2])
C0023413 (UMLS CUI [3])
Informed Consent
Item
signed informed consent
boolean
C0021430 (UMLS CUI [1])
Sensory neuropathy CTCAE Grades
Item
peripheral sensory neuropathy > or = grade 3.
boolean
C0151313 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Serum total bilirubin measurement
Item
serum bilirubin (total) > 3 x uln.
boolean
C1278039 (UMLS CUI [1])
Metastatic malignant neoplasm to brain Symptomatic | Metastatic malignant neoplasm to brain Uncontrolled
Item
symptomatic or uncontrolled brain metastasis.
boolean
C0220650 (UMLS CUI [1,1])
C0231220 (UMLS CUI [1,2])
C0220650 (UMLS CUI [2,1])
C0205318 (UMLS CUI [2,2])
Secondary malignant neoplasm of bone | Pleural effusion | Ascites
Item
metastases limited to bone, pleural effusion, or ascites.
boolean
C0153690 (UMLS CUI [1])
C0032227 (UMLS CUI [2])
C0003962 (UMLS CUI [3])
Heart Disease Uncontrolled
Item
uncontrolled overt cardiac disease.
boolean
C0018799 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Hypercalcemia Uncontrolled
Item
uncontrolled hypercalcemia.
boolean
C0020437 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Communicable Diseases Uncontrolled
Item
uncontrolled infections.
boolean
C0009450 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Uncontrolled hypertension
Item
uncontrolled hypertension (>180/110)
boolean
C1868885 (UMLS CUI [1])
Gastrointestinal perforation
Item
history of gi perforation.
boolean
C0151664 (UMLS CUI [1])
Arterial thromboembolism
Item
history of arterial thromboembolic events.
boolean
C3544094 (UMLS CUI [1])
Congestive heart failure
Item
history of congestive heart failure.
boolean
C0018802 (UMLS CUI [1])
Warfarin | Coumadin
Item
patients taking warfarin (coumadin).
boolean
C0043031 (UMLS CUI [1])
C0699129 (UMLS CUI [2])
Pregnancy
Item
patients who are pregnant.
boolean
C0032961 (UMLS CUI [1])