Study Subject Participation Status | Informed Consent
Item
during june 2004 and june 2005 who participate the clinical study "efficacy of pentoxifylline on chronic kidney disease" (clinicaltrials.gov identifier: nct00155246)and sign the informed consent.
boolean
C2348568 (UMLS CUI [1])
C0021430 (UMLS CUI [2])
Chronic kidney disease Disease length | Creatinine measurement, serum | Gender
Item
chronic kidney disease history > 3 months, serum creatinine: 1.1~6.0 mg/dl in female. 1.3~6.2 mg/dl in male.
boolean
C1561643 (UMLS CUI [1,1])
C0872146 (UMLS CUI [1,2])
C0201976 (UMLS CUI [2])
C0079399 (UMLS CUI [3])
Urine protein/creatinine ratio measurement Random Initial
Item
initial random urine protein (mg/dl) /creatinine (mg/dl) ratio > 0.5
boolean
C1096054 (UMLS CUI [1,1])
C0439605 (UMLS CUI [1,2])
C0205265 (UMLS CUI [1,3])
Pentoxifylline allergy
Item
history of allergy to pentoxifylline;
boolean
C0571995 (UMLS CUI [1])
Breast Feeding | Pregnancy
Item
females are nursing or pregnant;
boolean
C0006147 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
Urinary tract obstruction
Item
obstructive uropathy;
boolean
C0178879 (UMLS CUI [1])
Therapeutic immunosuppression chronic Stop Unable | Anti-Inflammatory Agents, Non-Steroidal
Item
unable to stop chronic immunosuppressive therapy, nsaid;
boolean
C0021079 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C1947925 (UMLS CUI [1,3])
C1299582 (UMLS CUI [1,4])
C0003211 (UMLS CUI [2])
Congestive heart failure New York Heart Association Classification
Item
congestive heart failure (new york heart association functional class iii or iv);
boolean
C0018802 (UMLS CUI [1,1])
C1275491 (UMLS CUI [1,2])
Angina, Unstable | Myocardial Infarction | Coronary Artery Bypass Surgery | Percutaneous Coronary Intervention
Item
unstable angina, myocardial infarction, coronary artery bypass graft surgery, percutaneous coronary intervention, within the past 6 months prior to signing the informed consent form;
boolean
C0002965 (UMLS CUI [1])
C0027051 (UMLS CUI [2])
C0010055 (UMLS CUI [3])
C1532338 (UMLS CUI [4])
Cerebral Hemorrhage
Item
cerebral hemorrhage within the past 6 months prior to signing the informed consent form;
boolean
C2937358 (UMLS CUI [1])
Retinal Hemorrhage
Item
retinal hemorrhage within the past 6 months prior to signing the informed consent form;
boolean
C0035317 (UMLS CUI [1])
Secondary hypertension | Secondary hypertension Suspected | Conn Syndrome | Hypertension, Renovascular | Pheochromocytoma
Item
known or suspected secondary hypertension (e.g., primary aldosteronism, renovascular hypertension, pheochromocytoma);
boolean
C0155616 (UMLS CUI [1])
C0155616 (UMLS CUI [2,1])
C0750491 (UMLS CUI [2,2])
C1384514 (UMLS CUI [3])
C0020545 (UMLS CUI [4])
C0031511 (UMLS CUI [5])
Uncontrolled hypertension Severe | Systolic Pressure | Diastolic blood pressure
Item
severe uncontrolled hypertension with sbp > 220 mmhg and/or dbp > 115 mmhg;
boolean
C1868885 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0871470 (UMLS CUI [2])
C0428883 (UMLS CUI [3])
Liver Dysfunction Laboratory Results | Alanine aminotransferase increased | Aspartate aminotransferase increased
Item
hepatic dysfunction as defined by the following laboratory parameters: alt or ast > 2 times the upper limit of the normal range;
boolean
C0086565 (UMLS CUI [1,1])
C1254595 (UMLS CUI [1,2])
C0151905 (UMLS CUI [2])
C0151904 (UMLS CUI [3])
Biliary obstruction | Cholestasis
Item
biliary obstructive disorders (e.g. cholestasis);
boolean
C0400979 (UMLS CUI [1])
C0008370 (UMLS CUI [2])
Malignant Neoplasm
Item
active malignancy
boolean
C0006826 (UMLS CUI [1])