Adult | Age
Item
adults age 18 thru 65
boolean
C0001675 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
Insulin-Like Growth Factor I | Normal Range Lower half field Age Specific | Normal Range Lower half field Gender Specific
Item
serum igf-1 in the lower half of the age and gender-specific normal range at the time of screening visit
boolean
C0021665 (UMLS CUI [1])
C0086715 (UMLS CUI [2,1])
C0439731 (UMLS CUI [2,2])
C0001779 (UMLS CUI [2,3])
C0205369 (UMLS CUI [2,4])
C0086715 (UMLS CUI [3,1])
C0439731 (UMLS CUI [3,2])
C0079399 (UMLS CUI [3,3])
C0205369 (UMLS CUI [3,4])
Hypertensive disease | Blood pressure | Antihypertensive therapy
Item
systemic hypertension, as defined as current bp >140/90 on screening visit, or taking anti-hypertensive therapy.
boolean
C0020538 (UMLS CUI [1])
C1271104 (UMLS CUI [2])
C0585941 (UMLS CUI [3])
Diabetes Mellitus | Fasting blood glucose measurement
Item
diabetes mellitus, as defined by known diagnosis or fasting blood glucose >126 at the time of screening visit.
boolean
C0011849 (UMLS CUI [1])
C0428568 (UMLS CUI [2])
Pregnancy | Breast Feeding | Serum Beta-HCG Test
Item
women who are pregnant or nursing, as confirmed by history or seum beta-hcg at the time of screening visit.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C1255526 (UMLS CUI [3])
Gender | Intake Estrogens Oral Exogenous
Item
women who are taking exogenous oral estrogens of any kind.
boolean
C0079399 (UMLS CUI [1])
C1512806 (UMLS CUI [2,1])
C0014939 (UMLS CUI [2,2])
C1527415 (UMLS CUI [2,3])
C0205228 (UMLS CUI [2,4])
Malignant Neoplasms | cancer recurrence | Skin carcinoma
Item
personal history of active cancer or recurrence within the past 10 years, with the exception of non-melanoma skin cancer.
boolean
C0006826 (UMLS CUI [1])
C0920420 (UMLS CUI [2])
C0699893 (UMLS CUI [3])
Benign Neoplasm Intracranial untreated
Item
personal history of an untreated benign intracranial neoplasm.
boolean
C0086692 (UMLS CUI [1,1])
C0524466 (UMLS CUI [1,2])
C0332155 (UMLS CUI [1,3])
Hydroxymethylglutaryl-CoA Reductase Inhibitors Therapeutic procedure Initiation
Item
initiation of statin therapy during the course of the study.
boolean
C0360714 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C1704686 (UMLS CUI [1,3])
Insulin-Like Growth Factor I Below normal Age Specific | Insulin-Like Growth Factor I Below normal Gender Specific
Item
a serum igf-1 level below the age and gender-specific normal range at the time of screening visit.
boolean
C0021665 (UMLS CUI [1,1])
C4047815 (UMLS CUI [1,2])
C0001779 (UMLS CUI [1,3])
C0205369 (UMLS CUI [1,4])
C0021665 (UMLS CUI [2,1])
C4047815 (UMLS CUI [2,2])
C0079399 (UMLS CUI [2,3])
C0205369 (UMLS CUI [2,4])
Renal Insufficiency | Glomerular Filtration Rate
Item
renal insufficiency, as defined by a gfr <60 mls/min/1.73 m2 upon renal function panel at the time of screening visit.
boolean
C1565489 (UMLS CUI [1])
C0017654 (UMLS CUI [2])
Hepatic Insufficiency | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
hepatic insufficiency, as defined by an ast and/or alt >twice the upper limit of normal at the time of screening visit.
boolean
C1306571 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])