Non-Small Cell Lung Carcinoma
Item
histologically proven non-small cell lung cancer
boolean
C0007131 (UMLS CUI [1])
Measurable Disease
Item
presence of measurable disease by recist
boolean
C1513041 (UMLS CUI [1])
TNM clinical staging Inoperable X-Ray Computed Tomography | Magnetic Resonance Imaging | TNM clinical staging Positron-Emission Tomography | TNM clinical staging Pathology
Item
inoperable stage iiia or iiib, proven by ct or mri (except wet t4). however, n2 or n3 should be confirmed by pet or pathology. (for t4, pet is optional)
boolean
C3258246 (UMLS CUI [1,1])
C0205187 (UMLS CUI [1,2])
C0040405 (UMLS CUI [1,3])
C0024485 (UMLS CUI [2])
C3258246 (UMLS CUI [3,1])
C0032743 (UMLS CUI [3,2])
C3258246 (UMLS CUI [4,1])
C0919386 (UMLS CUI [4,2])
Age
Item
18 years of age or older
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Chemotherapy | Therapeutic radiology procedure Chest | Immunotherapy | Biological treatment
Item
no prior chemotherapy, radiation therapy to chest, immunotherapy, or biologic therapy
boolean
C0392920 (UMLS CUI [1])
C1522449 (UMLS CUI [2,1])
C0817096 (UMLS CUI [2,2])
C0021083 (UMLS CUI [3])
C1531518 (UMLS CUI [4])
Hemoglobin measurement | Platelet Count measurement | Absolute neutrophil count
Item
serum hgb ≥ 10 gm/dl, platelet ≥ 100,000/μl, absolute neutrophil count ≥ 1,500/μl
boolean
C0518015 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
C0948762 (UMLS CUI [3])
Creatinine measurement, serum | Creatinine clearance measurement
Item
serum creatinine ≤1.25 x unl or creatinine clearance ≥60 mlml/min
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])
Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Alkaline phosphatase measurement
Item
serum bilirubin ≤ 1.5 x unl, ast (sgot) and alt (sgpt) ≤ 2.5 x unl, alkaline phosphatase ≤ 5 x unl
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201850 (UMLS CUI [4])
FEV1
Item
fev1> 0.8 l
boolean
C0748133 (UMLS CUI [1])
Informed Consent
Item
patients must sign an informed consent
boolean
C0021430 (UMLS CUI [1])
Carcinoid Tumor | Small cell carcinoma of lung
Item
carcinoid tumor, small cell carcinoma of lung
boolean
C0007095 (UMLS CUI [1])
C0149925 (UMLS CUI [2])
Distant metastasis
Item
patients with any distant metastasis
boolean
C1275402 (UMLS CUI [1])
Malignant Neoplasms | Basal cell carcinoma Cured | Carcinoma in situ of uterine cervix Cured
Item
history of another malignancy within the last five years except cured basal cell carcinoma of skin and cured carcinoma in-situ of uterine cervix
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2,1])
C1880198 (UMLS CUI [2,2])
C0851140 (UMLS CUI [3,1])
C1880198 (UMLS CUI [3,2])
Medical contraindication Chemotherapy | Communicable Disease | Myocardial Infarction | Heart Disease Symptomatic | Angina, Unstable | Congestive heart failure | Cardiac Arrhythmia Uncontrolled | Therapeutic immunosuppression
Item
any other morbidity or situation with contraindication for chemotherapy (e.g. active infection, myocardial infarction preceding 6 months, symptomatic heart disease including unstable angina, congestive heart failure or uncontrolled arrhythmias, immunosuppressive treatment)
boolean
C1301624 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0009450 (UMLS CUI [2])
C0027051 (UMLS CUI [3])
C0018799 (UMLS CUI [4,1])
C0231220 (UMLS CUI [4,2])
C0002965 (UMLS CUI [5])
C0018802 (UMLS CUI [6])
C0003811 (UMLS CUI [7,1])
C0205318 (UMLS CUI [7,2])
C0021079 (UMLS CUI [8])
Pregnancy | Breast Feeding | Gender Pregnancy Test Missing
Item
pregnant or lactating women, women who has not taken test of pregnancy (within 14 days before the first administration) and pregnant women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0079399 (UMLS CUI [3,1])
C0032976 (UMLS CUI [3,2])
C1705492 (UMLS CUI [3,3])
Childbearing Potential Contraceptive methods Unwilling
Item
women and men of childbearing potential who have no willing of employing adequate contraception
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])