Non-Small Cell Lung Carcinoma
Item
diagnosis of non-small cell lung cancer
boolean
C0007131 (UMLS CUI [1])
Measurable Disease | Evaluable Disease
Item
measurable or evaluable disease
boolean
C1513041 (UMLS CUI [1])
C1516986 (UMLS CUI [2])
primary tumor Histopathology finding
Item
primary tumor must be documented by histopathic analysis
boolean
C0677930 (UMLS CUI [1,1])
C0428093 (UMLS CUI [1,2])
Disease recurrence Biopsy
Item
disease recurrences occurring greater than five years after original diagnosis must be biopsy proven
boolean
C0679254 (UMLS CUI [1,1])
C0005558 (UMLS CUI [1,2])
Chemotherapy Regimen Quantity advanced disease | Neoadjuvant Therapy | Adjuvant therapy
Item
treatment with only one prior chemotherapy regimen for advanced disease (one additional prior regimen was allowed for neoadjuvant, adjuvant, or neoadjuvant plus adjuvant therapy)
boolean
C0392920 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
C0679246 (UMLS CUI [1,3])
C0600558 (UMLS CUI [2])
C0677850 (UMLS CUI [3])
Creatinine measurement, serum | Estimation of creatinine clearance by Cockcroft-Gault formula
Item
serum creatinine < 2mg/dl, or a calculated creatinine clearance > 40cc/min using the following formula: (140-age) x wt(kg) x 0.85 (if female 0.72) x creatinine (mg/dl). tests must be done within 28 days prior to registration
boolean
C0201976 (UMLS CUI [1])
C2711451 (UMLS CUI [2])
CT of chest and abdomen
Item
must have a ct scan (chest & abdomen) within 4 weeks prior to registration
boolean
C1630402 (UMLS CUI [1])
Zubrod Performance Status
Item
zubrod performance status of 0-3
boolean
C3714786 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
women who are pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Malignant Neoplasms | Basal cell carcinoma Treated | Squamous cell carcinoma of skin Treated | Carcinoma in situ of uterine cervix Treated | Malignant Neoplasm In complete remission TNM clinical staging | Malignant Neoplasm Disease Free of
Item
no other prior malignancy is allowed except for: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage i or ii cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for 5 years
boolean
C0006826 (UMLS CUI [1])
C0007117 (UMLS CUI [2,1])
C1522326 (UMLS CUI [2,2])
C0553723 (UMLS CUI [3,1])
C1522326 (UMLS CUI [3,2])
C0851140 (UMLS CUI [4,1])
C1522326 (UMLS CUI [4,2])
C0006826 (UMLS CUI [5,1])
C0677874 (UMLS CUI [5,2])
C3258246 (UMLS CUI [5,3])
C0006826 (UMLS CUI [6,1])
C0012634 (UMLS CUI [6,2])
C0332296 (UMLS CUI [6,3])
Ventricular Fibrillation | Sinus Node Dysfunction | Atrioventricular node Disease | Wolff-Parkinson-White Syndrome | Congestive heart failure Evidence of | Chest pain on exertion | Cardiac Arrhythmia Hemodynamic Significant | Cardiac Arrhythmia Life Threatening | Electrocardiogram: myocardial infarction Evidence of | Cardiac stress test normal | Age | Electrocardiogram abnormal | Heart Diseases
Item
history of ventricular fibrillation, sinus node or av nodal disease, wolff parkinson white syndrome, evidence of congestive heart failure, chest pain with exertion, hemodynamically significant or life threatening cardiac arrhythmia, or evidence of prior myocardial infarction on ekg. ekg must have been done within 28 days prior to registration. a normal cardiac stress test within 182 days prior to registration is required for all patients over 50 years old or those with abnormal ekg or any history of cardiac disease.
boolean
C0042510 (UMLS CUI [1])
C0428908 (UMLS CUI [2])
C1269553 (UMLS CUI [3,1])
C0012634 (UMLS CUI [3,2])
C0043202 (UMLS CUI [4])
C0018802 (UMLS CUI [5,1])
C0332120 (UMLS CUI [5,2])
C0232288 (UMLS CUI [6])
C0003811 (UMLS CUI [7,1])
C0019010 (UMLS CUI [7,2])
C0750502 (UMLS CUI [7,3])
C0003811 (UMLS CUI [8,1])
C2826244 (UMLS CUI [8,2])
C0428953 (UMLS CUI [9,1])
C0332120 (UMLS CUI [9,2])
C1096370 (UMLS CUI [10])
C0001779 (UMLS CUI [11])
C0522055 (UMLS CUI [12])
C0018799 (UMLS CUI [13])
Hypersensitivity erlotinib | Digoxin allergy
Item
hypersensitivity to erlotinib and/or digoxin
boolean
C0020517 (UMLS CUI [1,1])
C1135135 (UMLS CUI [1,2])
C0571956 (UMLS CUI [2])
Blood potassium abnormal | abnormal; blood level, magnesium | Blood calcium abnormal | Malnutrition | Severe diarrhea | Vomiting Prolonged | Dialysis | Suction gastrointestinal | Hypothyroidism untreated | Diuretics | Amphotericin B | Steroids | Antacids
Item
abnormal levels of k, mg, and/or ca, or conditions which cause such abnormalities (e.g. malnutrition, severe diarrhea, prolonged vomiting, dialysis, gi suction, untreated hypothyroidism, and use of diuretics, amphotericin b, steroids, or antacids)
boolean
C0853759 (UMLS CUI [1])
C0476333 (UMLS CUI [2])
C0853772 (UMLS CUI [3])
C0162429 (UMLS CUI [4])
C1443924 (UMLS CUI [5])
C0042963 (UMLS CUI [6,1])
C0439590 (UMLS CUI [6,2])
C0011946 (UMLS CUI [7])
C0038638 (UMLS CUI [8,1])
C0521362 (UMLS CUI [8,2])
C2749407 (UMLS CUI [9])
C0012798 (UMLS CUI [10])
C0002679 (UMLS CUI [11])
C0038317 (UMLS CUI [12])
C0003138 (UMLS CUI [13])