Gender Postmenopausal state | Noninfiltrating Intraductal Carcinoma | Menopause criteria
Item
postmenopausal women with newly diagnosed dcis. women will be considered to be in menopause if they fall into one of the following groups:
boolean
C0079399 (UMLS CUI [1,1])
C0232970 (UMLS CUI [1,2])
C0007124 (UMLS CUI [2])
C0025320 (UMLS CUI [3,1])
C0243161 (UMLS CUI [3,2])
Age
Item
age > 60
boolean
C0001779 (UMLS CUI [1])
Age | Amenorrhea disease length | Uterus Intact
Item
age > 45 with amenorrhea > 1 year with intact uterus
boolean
C0001779 (UMLS CUI [1])
C0002453 (UMLS CUI [2,1])
C0872146 (UMLS CUI [2,2])
C0042149 (UMLS CUI [3,1])
C0205266 (UMLS CUI [3,2])
Bilateral oophorectomy Status post
Item
status post bilateral oophorectomies
boolean
C0278321 (UMLS CUI [1,1])
C0231290 (UMLS CUI [1,2])
Follicle stimulating hormone measurement Range Postmenopausal | Estradiol measurement Range Postmenopausal
Item
fsh/estradiol levels in postmenopausal range for the institution
boolean
C0202022 (UMLS CUI [1,1])
C1514721 (UMLS CUI [1,2])
C0232970 (UMLS CUI [1,3])
C0337434 (UMLS CUI [2,1])
C1514721 (UMLS CUI [2,2])
C0232970 (UMLS CUI [2,3])
Noninfiltrating Intraductal Carcinoma Method of biopsy Minimally invasive | Vacuum-Assisted Biopsy | Mammotome
Item
dcis must have been diagnosed with a minimally invasive biopsy technique, such as a vacuum-assisted large core tool (mammotome) or an equivalent method.
boolean
C0007124 (UMLS CUI [1,1])
C0449327 (UMLS CUI [1,2])
C2711297 (UMLS CUI [1,3])
C1710607 (UMLS CUI [2])
C3273259 (UMLS CUI [3])
Biopsy Tissue specimen Available | Biological Markers performance
Item
there must be available tissue from the diagnostic biopsy to perform molecular markers.
boolean
C0005558 (UMLS CUI [1,1])
C1292533 (UMLS CUI [1,2])
C0470187 (UMLS CUI [1,3])
C0005516 (UMLS CUI [2,1])
C1882330 (UMLS CUI [2,2])
Mammography
Item
baseline mammogram within 8 weeks of study entry.
boolean
C0024671 (UMLS CUI [1])
Creatinine measurement, serum
Item
serum creatinine less than or equal to 2.0 mg/dl.
boolean
C0201976 (UMLS CUI [1])
Serum total bilirubin measurement | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Alkaline phosphatase measurement | Absolute neutrophil count | Platelet Count measurement | Hemoglobin measurement
Item
total bilirubin less than or equal to 2.0 upper limit of normal (uln), transaminases (sgot and/or sgpt) and alkaline phosphatase may be up to 2.5 x institutional upper limit of normal (uln), agc greater than or equal to 1500, platelets greater than or equal to 100,000, hemoglobin greater than or equal to 8.0 g/dl
boolean
C1278039 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0201850 (UMLS CUI [4])
C0948762 (UMLS CUI [5])
C0032181 (UMLS CUI [6])
C0518015 (UMLS CUI [7])
Peripheral Neuropathy CTCAE Grades
Item
peripheral neuropathy grade 0-1.
boolean
C0031117 (UMLS CUI [1,1])
C1516728 (UMLS CUI [1,2])
Therapeutic procedure Noninfiltrating Intraductal Carcinoma
Item
no prior therapy for dcis.
boolean
C0087111 (UMLS CUI [1,1])
C0007124 (UMLS CUI [1,2])
performance status
Item
swog performance status of less than or equal to 1
boolean
C1518965 (UMLS CUI [1])
Informed Consent
Item
all patients must provide informed written consent
boolean
C0021430 (UMLS CUI [1])
Hormone Therapy | Estrogen Antagonists | Estrogens | Selective Estrogen Receptor Modulators | Progestins | Aromatase Inhibitors
Item
prior hormonal therapy (antiestrogens, estrogen, serm's, progestins, or aromatase inhibitors) within 6 months of study entry.
boolean
C0279025 (UMLS CUI [1])
C0014930 (UMLS CUI [2])
C0014939 (UMLS CUI [3])
C0732611 (UMLS CUI [4])
C0033306 (UMLS CUI [5])
C0593802 (UMLS CUI [6])
Medical condition Excludes Therapeutic procedure | Mental condition Excludes Therapeutic procedure | Social Condition Excludes Therapeutic procedure
Item
underlying medical, psychiatric or social conditions that would preclude patient from receiving treatment.
boolean
C3843040 (UMLS CUI [1,1])
C0332196 (UMLS CUI [1,2])
C0087111 (UMLS CUI [1,3])
C3840291 (UMLS CUI [2,1])
C0332196 (UMLS CUI [2,2])
C0087111 (UMLS CUI [2,3])
C0037403 (UMLS CUI [3,1])
C0332196 (UMLS CUI [3,2])
C0087111 (UMLS CUI [3,3])
Deep Vein Thrombosis | Pulmonary Embolism
Item
history of dvt or pulmonary embolism
boolean
C0149871 (UMLS CUI [1])
C0034065 (UMLS CUI [2])