Gender | Outpatients european
Item
male or female european out-patients
boolean
C0079399 (UMLS CUI [1])
C0029921 (UMLS CUI [2,1])
C0239307 (UMLS CUI [2,2])
Age
Item
greater than or equal to 30 years of age
boolean
C0001779 (UMLS CUI [1])
Diabetes Mellitus, Non-Insulin-Dependent | Age
Item
type 2 diabetes first diagnosed at greater than or equal to 30 years of age
boolean
C0011860 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
24 hour urine protein excretion test Exclusive
Item
urinary protein excretion between 200-4000 mg/day exclusive
boolean
C0202204 (UMLS CUI [1,1])
C1548966 (UMLS CUI [1,2])
Sitting diastolic blood pressure mean
Item
mean sitting dbp less than or equal to 110 mghg
boolean
C1319894 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
Antihypertensive therapy Withdrawal | Therapeutic procedure Tolerable Poor | Therapeutic procedure Lack of Efficacy | Verification Therapeutic procedure Patient need for
Item
medically justifiable to withdraw antihypertensive treatment due to poor tolerability or inefficacy of previous treatment, or verification that treatment is still necessary
boolean
C0585941 (UMLS CUI [1,1])
C2349954 (UMLS CUI [1,2])
C0087111 (UMLS CUI [2,1])
C4053931 (UMLS CUI [2,2])
C0542537 (UMLS CUI [2,3])
C0087111 (UMLS CUI [3,1])
C0235828 (UMLS CUI [3,2])
C1711411 (UMLS CUI [4,1])
C0087111 (UMLS CUI [4,2])
C0686904 (UMLS CUI [4,3])
Pregnancy | Breast Feeding | Pregnancy, Planned | Childbearing Potential Contraceptive methods Lacking
Item
females pregnant, nursing or planning to become pregnant or were of childbearing potential and not using acceptable methods of contraception
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C0032992 (UMLS CUI [3])
C3831118 (UMLS CUI [4,1])
C0700589 (UMLS CUI [4,2])
C0332268 (UMLS CUI [4,3])
Secondary hypertension | Diabetic Nephropathy | Malignant Hypertension | Sitting diastolic blood pressure | Sitting systolic blood pressure
Item
secondary forms of hypertension other than diabetic nephropathy, malignant hypertension or patients with sitting dbp exceeding 110 mmhg or sitting sbp exceeding 200 mmhg
boolean
C0155616 (UMLS CUI [1])
C0011881 (UMLS CUI [2])
C0020540 (UMLS CUI [3])
C1319894 (UMLS CUI [4])
C1319893 (UMLS CUI [5])
Second degree atrioventricular block Evidence Electrocardiography | Complete atrioventricular block Evidence Electrocardiography | Atrial Fibrillation | Cardiac Arrhythmia Treatment required for | Bradycardia
Item
ecg evidence of 2nd or 3rd degree av-block, atrial fibrillation, cardiac arrhythmia (requiring therapy) or bradycardia
boolean
C0264906 (UMLS CUI [1,1])
C3887511 (UMLS CUI [1,2])
C1623258 (UMLS CUI [1,3])
C0151517 (UMLS CUI [2,1])
C3887511 (UMLS CUI [2,2])
C1623258 (UMLS CUI [2,3])
C0004238 (UMLS CUI [3])
C0003811 (UMLS CUI [4,1])
C0332121 (UMLS CUI [4,2])
C0428977 (UMLS CUI [5])
Cardiovascular Disease Significant
Item
presence of significant cardiovascular disease
boolean
C0007222 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
Cerebrovascular Disorder Significant | Gastrointestinal Disease Significant | Hematological Disease Significant | Liver disease Significant | Myocardial Infarction | Comorbidity Serious
Item
significant cerebrovascular disease, gastrointestinal, haematological or hepatic disease or myocardial infarction in last 12 months or a previous history of any serious underlying disease
boolean
C0007820 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0017178 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
C0018939 (UMLS CUI [3,1])
C0750502 (UMLS CUI [3,2])
C0023895 (UMLS CUI [4,1])
C0750502 (UMLS CUI [4,2])
C0027051 (UMLS CUI [5])
C0009488 (UMLS CUI [6,1])
C0205404 (UMLS CUI [6,2])
Kidney Disease | Nephrectomy | Kidney Transplantation | Creatinine measurement, serum | Creatinine clearance measurement
Item
concurrent renal disease, nephrectomy and/or renal transplant, serum creatinine level greater than or equal to 2.0 mg/dl or creatinine clearance clcr less than or equal to 50 ml/min
boolean
C0022658 (UMLS CUI [1])
C0027695 (UMLS CUI [2])
C0022671 (UMLS CUI [3])
C0201976 (UMLS CUI [4])
C0373595 (UMLS CUI [5])
LABORATORY ABNORMALITIES Clinical Significance | Aspartate aminotransferase measurement | Alanine aminotransferase measurement | Gamma-glutamyl transferase
Item
clinically significant lab abnormalities (asat/sgot, alat/sgpt and γ-gt )
boolean
C1853129 (UMLS CUI [1,1])
C2826293 (UMLS CUI [1,2])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
C0017040 (UMLS CUI [4])
Serum potassium measurement
Item
serum potassium level < 2.5 mmol/l or > 5.5 mmol/l
boolean
C0302353 (UMLS CUI [1])
Pharmaceutical Preparations Affecting Blood Pressure
Item
treatment of concurrent indications with drugs or medication which could have influenced bp
boolean
C0013227 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0005823 (UMLS CUI [1,3])
Hypersensitivity Angiotensin II receptor antagonist | Angiotensin II receptor antagonist Poor response to treatment | Medical contraindication Angiotensin II receptor antagonist | Hypersensitivity Hydrochlorothiazide | Hydrochlorothiazide Poor response to treatment | Medical contraindication Hydrochlorothiazide | Hypersensitivity Atenolol | Atenolol Poor response to treatment | Medical contraindication Atenolol | Hypersensitivity Pharmaceutical Preparations Related
Item
history of hypersensitivity, lack of response or contraindication to ang ii-antagonists, hctz or atenolol, or hypersensitivity to related drugs (cross-allergy)
boolean
C0020517 (UMLS CUI [1,1])
C0521942 (UMLS CUI [1,2])
C0521942 (UMLS CUI [2,1])
C1320680 (UMLS CUI [2,2])
C1301624 (UMLS CUI [3,1])
C0521942 (UMLS CUI [3,2])
C0020517 (UMLS CUI [4,1])
C0020261 (UMLS CUI [4,2])
C0020261 (UMLS CUI [5,1])
C1320680 (UMLS CUI [5,2])
C1301624 (UMLS CUI [6,1])
C0020261 (UMLS CUI [6,2])
C0020517 (UMLS CUI [7,1])
C0004147 (UMLS CUI [7,2])
C0004147 (UMLS CUI [8,1])
C1320680 (UMLS CUI [8,2])
C1301624 (UMLS CUI [9,1])
C0004147 (UMLS CUI [9,2])
C0020517 (UMLS CUI [10,1])
C0013227 (UMLS CUI [10,2])
C0439849 (UMLS CUI [10,3])