Age
Item
males or females ages 21 to 75
boolean
C0001779 (UMLS CUI [1])
Osteoarthritis of hip | Osteoarthritis, Knee
Item
has osteoarthritis of the hip or knee
boolean
C0029410 (UMLS CUI [1])
C0409959 (UMLS CUI [2])
Osteoarthritis | Pharmacotherapy Patient need for
Item
requires therapeutic doses of medications for osteoarthritis
boolean
C0029408 (UMLS CUI [1])
C0013216 (UMLS CUI [2,1])
C0686904 (UMLS CUI [2,2])
Childbearing Potential Lacking | Childbearing Potential Contraceptive methods
Item
if female, must be of non-childbearing potential or practicing birth control
boolean
C3831118 (UMLS CUI [1,1])
C0332268 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
Opioid use Sustained Pain Related
Item
has sufficient pain to justify the use of round-the-clock opioids
boolean
C0240602 (UMLS CUI [1,1])
C0443318 (UMLS CUI [1,2])
C0030193 (UMLS CUI [1,3])
C0439849 (UMLS CUI [1,4])
Therapeutic procedure Osteoarthritis | Pharmaceutical Preparations Osteoarthritis
Item
has received certain types of procedures or received certain medications for osteoarthritis within a specific timeframe
boolean
C0087111 (UMLS CUI [1,1])
C0029408 (UMLS CUI [1,2])
C0013227 (UMLS CUI [2,1])
C0029408 (UMLS CUI [2,2])
Medical condition Interferes with Pain Assessment
Item
has certain medical conditions which may interfere with pain assessments
boolean
C3843040 (UMLS CUI [1,1])
C0521102 (UMLS CUI [1,2])
C0030193 (UMLS CUI [1,3])
C1516048 (UMLS CUI [1,4])
Hypersensitivity Hydrocodone | Hypersensitivity Opioids | Hypersensitivity Acetaminophen | Reaction Serious Hydrocodone | Reaction Serious Opioids | Reaction Serious Acetaminophen
Item
is allergic to or has a serious reaction to hydrocodone, other opioids, or acetaminophen
boolean
C0020517 (UMLS CUI [1,1])
C0020264 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0242402 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0000970 (UMLS CUI [3,2])
C0443286 (UMLS CUI [4,1])
C0205404 (UMLS CUI [4,2])
C0020264 (UMLS CUI [4,3])
C0443286 (UMLS CUI [5,1])
C0205404 (UMLS CUI [5,2])
C0242402 (UMLS CUI [5,3])
C0443286 (UMLS CUI [6,1])
C0205404 (UMLS CUI [6,2])
C0000970 (UMLS CUI [6,3])
Communicable Diseases | Injuries | Illness
Item
has had certain infections, injuries or illnesses within the last month
boolean
C0009450 (UMLS CUI [1])
C3263723 (UMLS CUI [2])
C0221423 (UMLS CUI [3])
H/O: major abdominal surgery | Disease Causing Narrowing Intestinal | Constipation | Diarrhea | Nausea and vomiting
Item
has had major abdominal surgery, certain diseases that may cause intestinal narrowing, or has a history of constipation, diarrhea or nausea and vomiting
boolean
C0455612 (UMLS CUI [1])
C0012634 (UMLS CUI [2,1])
C0678227 (UMLS CUI [2,2])
C3854333 (UMLS CUI [2,3])
C0021853 (UMLS CUI [2,4])
C0009806 (UMLS CUI [3])
C0011991 (UMLS CUI [4])
C0027498 (UMLS CUI [5])
Chemotherapy | Malignant Neoplasms
Item
is receiving chemotherapy, or has been diagnosed with certain cancers within the past 5 years
boolean
C0392920 (UMLS CUI [1])
C0006826 (UMLS CUI [2])
Mental disorders Major | Antidepressant therapy Patient need for
Item
has a history of major psychiatric disorders or requires treatment with certain drugs for depression
boolean
C0004936 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C1096649 (UMLS CUI [2,1])
C0686904 (UMLS CUI [2,2])
Analgesics Discontinue Unable
Item
cannot discontinue pain medications, even for a short time, prior to the study start
boolean
C0002771 (UMLS CUI [1,1])
C1444662 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])