B-cell chronic lymphocytic leukemia variant | Rai Staging System
Item
b-cell chronic lymphocytic leukemia (a) rai stage 0-ii with indication for treatment by nci working group criteria: or (b) rai stage iii or iv.
boolean
C0475774 (UMLS CUI [1])
C1514715 (UMLS CUI [2])
Chemotherapy Regimen | Steroid therapy | Immunotherapy | Monoclonal Antibodies | Therapeutic radiology procedure
Item
received a minimum of one prior chemotherapy regimen. prior treatment with corticosteroids, immunotherapies, monoclonal antibodies or radiation therapy is permitted.
boolean
C0392920 (UMLS CUI [1])
C0149783 (UMLS CUI [2])
C0021083 (UMLS CUI [3])
C0003250 (UMLS CUI [4])
C1522449 (UMLS CUI [5])
Leukocytes
Item
white blood cell count > 25 x 10^9/l
boolean
C0023516 (UMLS CUI [1])
ECOG performance status
Item
ecog 0, 1,or 2.
boolean
C1520224 (UMLS CUI [1])
Renal function | Liver function
Item
adequate renal and hepatic function
boolean
C0232804 (UMLS CUI [1])
C0232741 (UMLS CUI [2])
undefined item
Item
platelets > 75 x 10^9/l, transfusion independent.
boolean
C0005821 (UMLS CUI [1])
C1879316 (UMLS CUI [2])
neutrophil | Transfusion (procedure)
Item
neutrophils > 1.0 x 10^9/l, transfusion independent
boolean
C0027950 (UMLS CUI [1])
C1879316 (UMLS CUI [2])
undefined item
Item
documented prolymphocytic leukemia (pll; prolymphocytes, 55% in blood)
boolean
C0023486 (UMLS CUI [1])
Cardiovascular Diseases | New York Heart Association Classification
Item
active cardiovascular disease as defined by nyha class iii-iv categorization.
boolean
C0007222 (UMLS CUI [1])
C1275491 (UMLS CUI [2])
Comorbidity; Affecting; Ribavirin
Item
intercurrent illness or medical condition precluding safe administration of ribavirin.
boolean
C0009488 (UMLS CUI [1,1])
C0392760 (UMLS CUI [1,2])
C0035525 (UMLS CUI [1,3])
Long-term current use of steroid
Item
concurrent use of chronic steroids, except as replacement therapy for adrenal insufficiency
boolean
C4039307 (UMLS CUI [1])
HIV Seropositivity | Hepatitis B | Hepatitis C
Item
known infection with hiv, hepatitis b or c.
boolean
C0019699 (UMLS CUI [1])
C0019163 (UMLS CUI [2])
C0019196 (UMLS CUI [3])
Comorbidity | Malignant neoplasm of skin; Carcinoma in Situ
Item
concurrent malignancy (other than resected basal or squamous cell skin cancers or in-situ carcinoma).
boolean
C0009488 (UMLS CUI [1])
C0007114 (UMLS CUI [2,1])
C0007099 (UMLS CUI [2,2])
Chronic Lymphocytic Leukemia; Therapeutic procedure
Item
received any previous therapy for cll within 28 days prior to study entry.
boolean
C0023434 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])