Aggressive Non-Hodgkin Lymphoma | WHO tumor classification
Item
the patients must have a histological diagnosis of aggressive non-hodgkin’s lymphoma including the following sub-categories of the who classification:
boolean
C1332225 (UMLS CUI [1])
C1301142 (UMLS CUI [2])
Diffuse Large B-Cell Lymphoma | Immunoblastic Large-Cell Lymphoma | Burkitt-like lymphoma | Sclerosis Mediastinum | Mucosa-Associated Lymphoid Tissue Lymphoma | T-Cell Lymphoma | Anaplastic large B-cell lymphoma
Item
diffuse large b-cell lymphoma and its variants (immunoblastic, burkitt-like, sclerosis of mediastinum, large b-cell malt, rich in t-cells and anaplastic b-cell lymphoma)
boolean
C0079744 (UMLS CUI [1])
C0079746 (UMLS CUI [2])
C1368771 (UMLS CUI [3])
C0036429 (UMLS CUI [4,1])
C0025066 (UMLS CUI [4,2])
C0242647 (UMLS CUI [5])
C0079772 (UMLS CUI [6])
C1321546 (UMLS CUI [7])
Peripheral T-Cell Lymphoma
Item
peripheral t-cell lymphoma
boolean
C0079774 (UMLS CUI [1])
Large cell anaplastic lymphoma T cell and Null cell type
Item
anaplastic lymphoma of large t-cells /null cells
boolean
C3838707 (UMLS CUI [1])
chemotherapeutics regimen first line of treatment | Anthracyclines | rituximab | Disease Progression Evidence of | Refractory Disease
Item
patients are eligible if they have documented evidence of progression after prior first-line chemotherapy containing anthracyclines associated or not with rituximab. patients with refractory disease to first line of treatment are also eligible.
boolean
C2045825 (UMLS CUI [1])
C0282564 (UMLS CUI [2])
C0393022 (UMLS CUI [3])
C0242656 (UMLS CUI [4,1])
C0332120 (UMLS CUI [4,2])
C1514815 (UMLS CUI [5])
ECOG performance status
Item
ecog ps (performance status) less than or equal to 2
boolean
C1520224 (UMLS CUI [1])
Measurable Disease 2-Dimensional
Item
presence of bidimensionally measurable disease in accordance with who criteria.
boolean
C1513041 (UMLS CUI [1,1])
C1705052 (UMLS CUI [1,2])
Central Nervous System Involvement
Item
involvement of the cns.
boolean
C4050309 (UMLS CUI [1])
Medical condition Contraindication Cisplatin
Item
any medical condition which contraindicates the degree of hydration required for the safe use of cisplatin.
boolean
C3843040 (UMLS CUI [1,1])
C1301624 (UMLS CUI [1,2])
C0008838 (UMLS CUI [1,3])
Intermediate-Grade Lymphoma Derived Malignant lymphoma unclassifiable low grade
Item
intermediate degree lymphoma derived from the malignant transformation of a previous low-grade lymphoma.
boolean
C0079741 (UMLS CUI [1,1])
C1441547 (UMLS CUI [1,2])
C0854880 (UMLS CUI [1,3])
Communicable Disease
Item
active infection (in the opinion of the investigator).
boolean
C0009450 (UMLS CUI [1])