Multiple Myeloma | Staging
Item
active multiple myeloma stage ii or iii durie salmon
boolean
C0026764 (UMLS CUI [1])
C0332305 (UMLS CUI [2])
Multiple Myeloma Serum paraprotein level result | Multiple Myeloma Urine paraprotein level result | Specimen Collection 24 Hours
Item
measurable levels of myeloma paraprotein in serum (≥1.0g/dl) or urine (≥ 0.2g excreted in a 24-hour collection sample)
boolean
C0026764 (UMLS CUI [1,1])
C1318383 (UMLS CUI [1,2])
C0026764 (UMLS CUI [2,1])
C1318384 (UMLS CUI [2,2])
C0200345 (UMLS CUI [3,1])
C1442770 (UMLS CUI [3,2])
ECOG performance status
Item
eastern cooperative oncology group (ecog) performance status of 0, 1, 2
boolean
C1520224 (UMLS CUI [1])
Childbearing Potential Sexual Abstinence | Childbearing Potential Contraceptive methods Quantity | Hormonal contraception | Tubal Ligation | Contraception, Barrier | Latex condom | Vaginal contraceptive diaphragm
Item
women of child bearing potential must agree to abstain for heterosexual intercourse or use 2 methods of contraception, one effective (for example hormonal or tubal ligation) and one barrier (for example latex condom, diaphragm)
boolean
C3831118 (UMLS CUI [1,1])
C0036899 (UMLS CUI [1,2])
C3831118 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C1265611 (UMLS CUI [2,3])
C2985296 (UMLS CUI [3])
C0520483 (UMLS CUI [4])
C0004764 (UMLS CUI [5])
C3873750 (UMLS CUI [6])
C0042241 (UMLS CUI [7])
Gender Sex Behavior Contraception, Barrier | Gender Sex Behavior Latex condom
Item
males must agree to use barrier contraception (latex condoms) when engaging in reproductive activity
boolean
C0079399 (UMLS CUI [1,1])
C0036864 (UMLS CUI [1,2])
C0004764 (UMLS CUI [1,3])
C0079399 (UMLS CUI [2,1])
C0036864 (UMLS CUI [2,2])
C3873750 (UMLS CUI [2,3])
Pregnancy | Breast Feeding
Item
pregnant or lactating females
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Peripheral Neuropathy | CTCAE Grades
Item
peripheral neuropathy ≥ to grade 2 of the nci ctc.
boolean
C0031117 (UMLS CUI [1])
C1516728 (UMLS CUI [2])
Malignant Neoplasms
Item
prior history of malignancy unless subject has been free of disease for ≥ 3 years
boolean
C0006826 (UMLS CUI [1])
LABORATORY ABNORMALITIES | Absolute neutrophil count
Item
lab abnormality: absolute neutrophil count (anc) <1,000 cells/mm^3 (1.0 x 10^9/l)
boolean
C1853129 (UMLS CUI [1])
C0948762 (UMLS CUI [2])
LABORATORY ABNORMALITIES | Platelet Count measurement
Item
lab abnormality: platelet count <50,000/mm^3 (50.0 x 10^9/l)
boolean
C1853129 (UMLS CUI [1])
C0032181 (UMLS CUI [2])
LABORATORY ABNORMALITIES | Creatinine measurement, serum
Item
lab abnormality: serum creatinine >3.0 mg/dl (265 µmol/l)
boolean
C1853129 (UMLS CUI [1])
C0201976 (UMLS CUI [2])
LABORATORY ABNORMALITIES | Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
lab abnormality: serum glutamic oxaloacetic transaminase (sgot) /aspartate aminotransferase (ast) or serum glutamic pyruvic transaminase (sgpt)/alanine transaminase (alt) >3.0 x upper limit of normal (uln)
boolean
C1853129 (UMLS CUI [1])
C0201899 (UMLS CUI [2])
C0201836 (UMLS CUI [3])
LABORATORY ABNORMALITIES | Serum total bilirubin measurement
Item
lab abnormality: serum total bilirubin > 2.0 mg/dl (34 µmol/l)
boolean
C1853129 (UMLS CUI [1])
C1278039 (UMLS CUI [2])