Major Depressive Disorder
Item
diagnosis of major depressive disorder
boolean
C1269683 (UMLS CUI [1])
Hamilton rating scale for depression
Item
hrsd(17) score of at least 14
boolean
C0451203 (UMLS CUI [1])
Sleeplessness | Subjective insomnia complaint
Item
presence and complaint of insomnia for at least 1 month
boolean
C0917801 (UMLS CUI [1])
C0865378 (UMLS CUI [2])
Able to speak fluently English Language
Item
fluent in english
boolean
C0564241 (UMLS CUI [1,1])
C0376245 (UMLS CUI [1,2])
Contraceptive methods
Item
use of an effective form of contraception throughout the study
boolean
C0700589 (UMLS CUI [1])
Mental disorders | Bipolar Disorder | Post-Traumatic Stress Disorder | Obsessive-Compulsive Disorder | Eating Disorders
Item
other psychiatric disorders (e.g., bipolar disorder, post traumatic stress disorder, obsessive compulsive disorder, eating disorder)
boolean
C0004936 (UMLS CUI [1])
C0005586 (UMLS CUI [2])
C0038436 (UMLS CUI [3])
C0028768 (UMLS CUI [4])
C0013473 (UMLS CUI [5])
Psychotic symptom
Item
psychotic symptoms
boolean
C0871189 (UMLS CUI [1])
Medical condition Serious | Medical condition Unstable | Medical condition End-stage
Item
serious, unstable, or terminal medical condition
boolean
C3843040 (UMLS CUI [1,1])
C0205404 (UMLS CUI [1,2])
C3843040 (UMLS CUI [2,1])
C0443343 (UMLS CUI [2,2])
C3843040 (UMLS CUI [3,1])
C0205088 (UMLS CUI [3,2])
Axis II diagnosis | Antisocial Personality Disorder | Schizotypal Personality Disorder | Borderline Personality Disorder Severe
Item
axis ii diagnosis of antisocial, schizotypal, or severe borderline personality disorder
boolean
C0270288 (UMLS CUI [1])
C0003431 (UMLS CUI [2])
C0036363 (UMLS CUI [3])
C0006012 (UMLS CUI [4,1])
C0205082 (UMLS CUI [4,2])
Substance Use Disorders
Item
substance abuse
boolean
C0038586 (UMLS CUI [1])
Psychiatric therapeutic procedure To be stopped Unwilling
Item
not willing to end other psychiatric treatment
boolean
C0204523 (UMLS CUI [1,1])
C1272691 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
Electroconvulsive Therapy | Vagus Nerve Stimulation
Item
previous electroconvulsive therapy or vagus nerve stimulation treatment during the last year
boolean
C0013806 (UMLS CUI [1])
C2350432 (UMLS CUI [2])
Sleep Apnea Syndromes | Restless Legs Syndrome | Nocturnal Myoclonus Syndrome
Item
sleep apnea, restless leg, or periodic limb movement disorder (to be ruled out after first sleep study)
boolean
C0037315 (UMLS CUI [1])
C0035258 (UMLS CUI [2])
C0751774 (UMLS CUI [3])
Sleep Disorders
Item
other sleep disorders
boolean
C0851578 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
currently pregnant or breastfeeding
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Epilepsy
Item
history of seizure disorder
boolean
C0014544 (UMLS CUI [1])
Disease Resulting in Metabolism altered | Disease Resulting in Response Hemodynamic | Condition Resulting in Metabolism altered | Condition Resulting in Response Hemodynamic
Item
disease or condition that produces altered metabolism or hemodynamic responses
boolean
C0012634 (UMLS CUI [1,1])
C0332294 (UMLS CUI [1,2])
C0025519 (UMLS CUI [1,3])
C0392747 (UMLS CUI [1,4])
C0012634 (UMLS CUI [2,1])
C0332294 (UMLS CUI [2,2])
C0871261 (UMLS CUI [2,3])
C0019010 (UMLS CUI [2,4])
C0348080 (UMLS CUI [3,1])
C0332294 (UMLS CUI [3,2])
C0025519 (UMLS CUI [3,3])
C0392747 (UMLS CUI [3,4])
C0348080 (UMLS CUI [4,1])
C0332294 (UMLS CUI [4,2])
C0871261 (UMLS CUI [4,3])
C0019010 (UMLS CUI [4,4])
Liver Dysfunction | Renal dysfunction
Item
liver or kidney dysfunction
boolean
C0086565 (UMLS CUI [1])
C3279454 (UMLS CUI [2])
taking over-the-counter medication Mood benefit | Herbs--Therapeutic use Mood benefit | taking over-the-counter medication Sleep benefit | Herbs--Therapeutic use Sleep benefit | Melatonin | Valerian | Kava preparation | Hova | Hypericum perforatum
Item
current use of any over the counter medications or herbs for mood or sleep benefits (e.g., melatonin, valerian, kava, hop extract, st. john's wort, same)
boolean
C2054160 (UMLS CUI [1,1])
C0026516 (UMLS CUI [1,2])
C0814225 (UMLS CUI [1,3])
C3826216 (UMLS CUI [2,1])
C0026516 (UMLS CUI [2,2])
C0814225 (UMLS CUI [2,3])
C2054160 (UMLS CUI [3,1])
C0037313 (UMLS CUI [3,2])
C0814225 (UMLS CUI [3,3])
C3826216 (UMLS CUI [4,1])
C0037313 (UMLS CUI [4,2])
C0814225 (UMLS CUI [4,3])
C0025219 (UMLS CUI [5])
C0042281 (UMLS CUI [6])
C0939882 (UMLS CUI [7])
C0062977 (UMLS CUI [8])
C0936242 (UMLS CUI [9])