Aggressive Non-Hodgkin Lymphoma CD20 antigen positive | Intermediate Grade B-Cell Non-Hodgkin's Lymphoma | High Grade B-Cell Non-Hodgkin's Lymphoma
Item
histologically documented, aggressive and/or intermediate grade and high-grade b cell nhl, cd20 positive.
boolean
C1332225 (UMLS CUI [1,1])
C3888518 (UMLS CUI [1,2])
C1512858 (UMLS CUI [2])
C1512431 (UMLS CUI [3])
Lymphoma, Large-Cell, Follicular | lymphoma; cleaved cell, small cell (diffuse) | Diffuse Mixed-Cell Lymphoma | Diffuse Large B-Cell Lymphoma | Anaplastic large B-cell lymphoma | Mantle cell lymphoma
Item
histologic subtypes include follicular large cell, diffuse small cleaved cell, diffuse mixed small and large cell, diffuse large cell, anaplastic large cell, and mantle cell lymphomas.
boolean
C0079745 (UMLS CUI [1])
C1398349 (UMLS CUI [2])
C0079757 (UMLS CUI [3])
C0079744 (UMLS CUI [4])
C1321546 (UMLS CUI [5])
C0334634 (UMLS CUI [6])
Lymphoma, Non-Hodgkin | Lymphoma, Intermediate-Grade | High Grade Lymphoma | International Prognostic Index | Mantle cell lymphoma
Item
nhl must have high-intermediate or high international prognostic index (standard ipi) score at diagnosis. mantle cell nhl is eligible regardless of ipi score.
boolean
C0024305 (UMLS CUI [1])
C0079741 (UMLS CUI [2])
C0079740 (UMLS CUI [3])
C1512894 (UMLS CUI [4])
C0334634 (UMLS CUI [5])
First line treatment In complete remission | First line treatment partial response
Item
complete or partial response to first-line therapy.
boolean
C1708063 (UMLS CUI [1,1])
C0677874 (UMLS CUI [1,2])
C1708063 (UMLS CUI [2,1])
C1521726 (UMLS CUI [2,2])
CNS disorder Treated | Meningeal disorder Treated | Therapeutic radiology procedure | intrathecal chemotherapy | Cerebrospinal Fluid Negative
Item
treated cns or meningeal disease, using radiation therapy and/or intrathecal chemotherapy, is allowed. patients with meningeal disease must have cytologically negative csf at time of study entry.
boolean
C0007682 (UMLS CUI [1,1])
C1522326 (UMLS CUI [1,2])
C0154728 (UMLS CUI [2,1])
C1522326 (UMLS CUI [2,2])
C1522449 (UMLS CUI [3])
C1517560 (UMLS CUI [4])
C0007806 (UMLS CUI [5,1])
C1513916 (UMLS CUI [5,2])
Doxorubicin Cumulative Dose
Item
cumulative total doxorubicin: <500 mg/m2
boolean
C0013089 (UMLS CUI [1,1])
C2986497 (UMLS CUI [1,2])
performance status
Item
performance score 0-2
boolean
C1518965 (UMLS CUI [1])
curative treatment Malignant Neoplasms | Disease Evidence
Item
patients with a prior malignancy are eligible if they were treated with curative intent and have no evidence of active disease.
boolean
C1273390 (UMLS CUI [1,1])
C0006826 (UMLS CUI [1,2])
C0012634 (UMLS CUI [2,1])
C3887511 (UMLS CUI [2,2])
Pregnancy | Breast Feeding
Item
patients must not be pregnant or nursing.
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Informed Consent
Item
informed consent
boolean
C0021430 (UMLS CUI [1])
Pregnancy | Breast Feeding
Item
pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])