Non-Small Cell Lung Carcinoma | TNM clinical staging
Item
histologically confirmed stage iiia or iiib nsclc
boolean
C0007131 (UMLS CUI [1])
C3258246 (UMLS CUI [2])
Measurable Disease
Item
patients must have measurable disease
boolean
C1513041 (UMLS CUI [1])
Prior Chemotherapy Non-Small Cell Lung Carcinoma | prior radiation therapy Non-Small Cell Lung Carcinoma | systemic therapy Non-Small Cell Lung Carcinoma
Item
no previous chemotherapy, radiation therapy or other systemic therapy for their nsclc.
boolean
C1514457 (UMLS CUI [1,1])
C0007131 (UMLS CUI [1,2])
C0279134 (UMLS CUI [2,1])
C0007131 (UMLS CUI [2,2])
C1515119 (UMLS CUI [3,1])
C0007131 (UMLS CUI [3,2])
Age
Item
age>18 years
boolean
C0001779 (UMLS CUI [1])
Life Expectancy
Item
life expectancy >12 months
boolean
C0023671 (UMLS CUI [1])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
organ function | Bone Marrow function
Item
normal organ and marrow function
boolean
C0678852 (UMLS CUI [1])
C0005953 (UMLS CUI [2,1])
C0031843 (UMLS CUI [2,2])
Medically fit for surgery
Item
medically fit for surgery at time of enrollment.
boolean
C4075860 (UMLS CUI [1])
Childbearing Potential Contraceptive methods | Gender Contraceptive methods | Gender Pregnancy test negative
Item
women of childbearing potential and men must agree to use adequate contraception prior to study entry and for the duration of the study. women must have a negative pregnancy test prior to enrollment.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
C0079399 (UMLS CUI [2,1])
C0700589 (UMLS CUI [2,2])
C0079399 (UMLS CUI [3,1])
C0427780 (UMLS CUI [3,2])
Informed Consent
Item
ability to understand and willingness to sign the consent form.
boolean
C0021430 (UMLS CUI [1])
Prior Chemotherapy Non-Small Cell Lung Carcinoma | prior radiation therapy Non-Small Cell Lung Carcinoma | systemic therapy Non-Small Cell Lung Carcinoma
Item
previous chemotherapy, radiation therapy or any other systemic treatment for their nsclc.
boolean
C1514457 (UMLS CUI [1,1])
C0007131 (UMLS CUI [1,2])
C0279134 (UMLS CUI [2,1])
C0007131 (UMLS CUI [2,2])
C1515119 (UMLS CUI [3,1])
C0007131 (UMLS CUI [3,2])
Investigational New Drugs
Item
patients receiving any other investigational agents.
boolean
C0013230 (UMLS CUI [1])
Neoplasm Metastasis | Metastatic malignant neoplasm to brain
Item
known metastatic disease (brain or any other site)
boolean
C0027627 (UMLS CUI [1])
C0220650 (UMLS CUI [2])
severe allergy docetaxel | severe allergy Polysorbate 80 | Allergic Reaction Carboplatin | Allergic Reaction Compound Similar | Allergic Reaction Investigational New Drugs
Item
history of severe hypersensitivity reaction to docetaxel or other drugs formulated with polysorbate 80 or with allergic reactions to compounds of similar chemical composition to carboplatin or other agents used in the study.
boolean
C2945656 (UMLS CUI [1,1])
C0246415 (UMLS CUI [1,2])
C2945656 (UMLS CUI [2,1])
C0032601 (UMLS CUI [2,2])
C1527304 (UMLS CUI [3,1])
C0079083 (UMLS CUI [3,2])
C1527304 (UMLS CUI [4,1])
C1706082 (UMLS CUI [4,2])
C2348205 (UMLS CUI [4,3])
C1527304 (UMLS CUI [5,1])
C0013230 (UMLS CUI [5,2])
Peripheral Neuropathy | CTCAE Grades
Item
peripheral neuropathy >grade 1
boolean
C0031117 (UMLS CUI [1])
C1516728 (UMLS CUI [2])
Comorbidity Uncontrolled
Item
uncontrolled concurrent illness
boolean
C0009488 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Pregnancy
Item
pregnant women
boolean
C0032961 (UMLS CUI [1])
Weight decreased Percentage
Item
weight loss>10% in the past 3 months before diagnosis.
boolean
C1262477 (UMLS CUI [1,1])
C0439165 (UMLS CUI [1,2])
Hyperglycemia | Positron-Emission Tomography Exclusion of
Item
hyperglycemia - exclusion from pet analysis
boolean
C0020456 (UMLS CUI [1])
C0032743 (UMLS CUI [2,1])
C2828389 (UMLS CUI [2,2])
HIV Seropositivity | Antiretroviral therapy Combined | Drug Interactions Associated with docetaxel | Drug Interactions Associated with Carboplatin
Item
hiv positive patients receiving combination anti-retroviral therapy because of possible pharmacokinetic interactions with docetaxel and carboplatin or other agents administered during the study.
boolean
C0019699 (UMLS CUI [1])
C1963724 (UMLS CUI [2,1])
C0205195 (UMLS CUI [2,2])
C0687133 (UMLS CUI [3,1])
C0332281 (UMLS CUI [3,2])
C0246415 (UMLS CUI [3,3])
C0687133 (UMLS CUI [4,1])
C0332281 (UMLS CUI [4,2])
C0079083 (UMLS CUI [4,3])