Primary invasive malignant neoplasm of female breast
Item
histological confirmation of primary invasive breast cancer
boolean
C4076461 (UMLS CUI [1])
Breast Carcinoma Operable | TNM clinical staging
Item
stage i-iii operable breast cancer.
boolean
C0678222 (UMLS CUI [1,1])
C0205188 (UMLS CUI [1,2])
C3258246 (UMLS CUI [2])
primary tumor size | Radiographic imaging | Palpation
Item
primary tumor must be greater than or equal to 2cm by radiographic imaging or palpitation
boolean
C0677930 (UMLS CUI [1,1])
C0456389 (UMLS CUI [1,2])
C0457276 (UMLS CUI [2])
C0030247 (UMLS CUI [3])
Gender | Age
Item
women greater than 18 years of age
boolean
C0079399 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
White Blood Cell Count procedure
Item
wbc > 4000/mm3
boolean
C0023508 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count > 100,000/mm3
boolean
C0032181 (UMLS CUI [1])
Aspartate aminotransferase measurement
Item
sgot < 2x uln
boolean
C0201899 (UMLS CUI [1])
Creatinine clearance measurement
Item
calculated creatinine clearance > 50ml/min
boolean
C0373595 (UMLS CUI [1])
Neoplasm Metastasis Evidence of | Carcinoma breast stage IV | Physical Examination | Diagnostic tests
Item
evidence of metastatic (stage iv) cancer on physical exam or any diagnostic study.
boolean
C0027627 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0278488 (UMLS CUI [2])
C0031809 (UMLS CUI [3])
C0086143 (UMLS CUI [4])
Pregnancy | Breast Feeding
Item
pregnant or breast-feeding women
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Inflammatory Breast Carcinoma
Item
inflammatory breast cancer
boolean
C0278601 (UMLS CUI [1])
HER2-positive carcinoma of breast
Item
her2 positive disease
boolean
C1960398 (UMLS CUI [1])
Hypersensitivity Fluorouracil | Dihydropyrimidine Dehydrogenase Deficiency
Item
history of hypersensitivity to a 5-fu or known dihydropyrimidine dehydrogenase (dpd) deficiency
boolean
C0020517 (UMLS CUI [1,1])
C0016360 (UMLS CUI [1,2])
C1959620 (UMLS CUI [2])
Intercurrent disease Uncontrolled
Item
uncontrolled intercurrent illness
boolean
C0277557 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
Breast Carcinoma Previous | irradiation of breast Previous | Prior Chemotherapy | Prior Chemotherapy High dose | Stem cell transplant | Bone Marrow Transplantation
Item
prior history of breast cancer are ineligible except: diagnosed at least 2 years ago; present cancer is not in previously irradiated breast; no prior chemotherapy in the past 5 years; no prior high-dose chemotherapy with stem cell or bone marrow transplant.
boolean
C0678222 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C2148528 (UMLS CUI [2,1])
C0205156 (UMLS CUI [2,2])
C1514457 (UMLS CUI [3])
C1514457 (UMLS CUI [4,1])
C0444956 (UMLS CUI [4,2])
C1504389 (UMLS CUI [5])
C0005961 (UMLS CUI [6])
Excision biopsy
Item
excisional biopsy performed prior to enrollment
boolean
C0184921 (UMLS CUI [1])
Blood Coagulation Disorder Uncontrolled
Item
uncontrolled coagulopathy
boolean
C0005779 (UMLS CUI [1,1])
C0205318 (UMLS CUI [1,2])
upper gastrointestinal tract Integrity Physical Lacking | Malabsorption Syndrome
Item
lack of physical integrity of the upper gastrointestinal tract or malabsorption syndrome.
boolean
C1268997 (UMLS CUI [1,1])
C1947912 (UMLS CUI [1,2])
C0205485 (UMLS CUI [1,3])
C0332268 (UMLS CUI [1,4])
C0024523 (UMLS CUI [2])