Physical Inactivity Duration | Sedentary lifestyle | Energy Metabolism Kcal/kg/day
Item
physically inactive for 6 months prior to study entry; defined as sedentary and having an energy expenditure of less than 35 kcal(kgˉ¹)(dayˉ¹)
boolean
C3890554 (UMLS CUI [1,1])
C0449238 (UMLS CUI [1,2])
C1532253 (UMLS CUI [2])
C0014272 (UMLS CUI [3,1])
C1690969 (UMLS CUI [3,2])
Postmenopausal state | Age | Menstruation absent Duration | Follicle stimulating hormone level | Hysterectomy | Bilateral oophorectomy | Estradiol level
Item
postmenopausal and fits one of the following criteria: over 55 years old and no natural menses for at least 5 years; less than 55 years old and no natural menses for at least 2 years and a serum follicle stimulating hormone (fsh) level greater than 40 miu/ml; hysterectomy with documentation of bilateral oophorectomy; less than 55 years old with a hysterectomy but no documentation of bilateral oophorectomy and with an fsh level greater than 40 miu/ml and estradiol level less than 25 pg/ml
boolean
C0232970 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
C0497456 (UMLS CUI [3,1])
C0449238 (UMLS CUI [3,2])
C0428406 (UMLS CUI [4])
C0020699 (UMLS CUI [5])
C0278321 (UMLS CUI [6])
C1443016 (UMLS CUI [7])
Hormone replacement therapy | Pharmaceutical Preparations Dosage Stable
Item
if taking hormone replacement therapy, must have been on a stable dose for at least 6 months, and must maintain the same dosage of the same medication throughout the study
boolean
C0282402 (UMLS CUI [1])
C0013227 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0205360 (UMLS CUI [2,3])
Body mass index
Item
body mass index between 25 and 40 kg/m²
boolean
C1305855 (UMLS CUI [1])
Systolic Pressure | Diastolic blood pressure
Item
systolic blood pressure between 120 and 159 mm hg and diastolic blood pressure no greater than 99 mm hg
boolean
C0871470 (UMLS CUI [1])
C0428883 (UMLS CUI [2])
Plasma fasting glucose measurement
Item
fasting plasma glucose level less than 126 mg/dl
boolean
C0583513 (UMLS CUI [1])
Exercise Capability
Item
physically capable of exercise
boolean
C0015259 (UMLS CUI [1,1])
C2698977 (UMLS CUI [1,2])
Antihypertensive Agents
Item
currently taking any antihypertensive medications
boolean
C0003364 (UMLS CUI [1])
Cardiovascular Diseases Significant | Cardiac Arrhythmia | Myocarditis | Cardiomyopathies | Congestive heart failure | Cerebrovascular accident | Transient Ischemic Attack | Peripheral Vascular Diseases | Intermittent Claudication | Thrombophlebitis | THROMBOPHLEBITIS CHRONIC | Recurrent thrombophlebitis | Hypertensive disease
Item
current or history of significant cardiovascular diseases or disorders, including arrythmias; myocarditis; cardiomyopathy; congestive heart failure; stroke or transient ischemic cerebral attacks; peripheral vascular disease with intermittent claudication; acute, chronic, or recurrent thrombophlebitis; and stage ii or iii hypertension
boolean
C0007222 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0003811 (UMLS CUI [2])
C0027059 (UMLS CUI [3])
C0878544 (UMLS CUI [4])
C0018802 (UMLS CUI [5])
C0038454 (UMLS CUI [6])
C0007787 (UMLS CUI [7])
C0085096 (UMLS CUI [8])
C0021775 (UMLS CUI [9])
C0040046 (UMLS CUI [10])
C0749399 (UMLS CUI [11])
C3550150 (UMLS CUI [12])
C0020538 (UMLS CUI [13])
Serum total cholesterol measurement | Low density lipoprotein cholesterol measurement | Triglycerides measurement
Item
current or history of total cholesterol level of at least 240 mg/dl with ldl-c level of at least 160 mg/dl or triglyceride levels of at least 300 mg/dl
boolean
C1445957 (UMLS CUI [1])
C0202117 (UMLS CUI [2])
C0202236 (UMLS CUI [3])
Hematological Disease | Anemia | Blood Coagulation Disorders | Thrombosis chronic | Thrombophilia
Item
current or history of hematologic disorders, including anemias, bleeding disorders, chronic thrombotic disorders, or hypercoagulable states
boolean
C0018939 (UMLS CUI [1])
C0002871 (UMLS CUI [2])
C0005779 (UMLS CUI [3])
C0040053 (UMLS CUI [4,1])
C0205191 (UMLS CUI [4,2])
C0398623 (UMLS CUI [5])
Blood Donation Recent
Item
recent blood donation within the 6 weeks before study entry (participants also will be asked to refrain from blood donation during the study)
boolean
C0005794 (UMLS CUI [1,1])
C0332185 (UMLS CUI [1,2])
Weight decreased Quantity
Item
weight loss of 20 or more kilograms within the year prior to study entry
boolean
C1262477 (UMLS CUI [1,1])
C1265611 (UMLS CUI [1,2])
Hospitalization Mental disorders
Item
hospitalization for mental illness within 5 years of study entry or score of at least 10 on the center for epidemiological studies depression scale (cesd)
boolean
C0019993 (UMLS CUI [1,1])
C0004936 (UMLS CUI [1,2])
Absence City Duration Planned
Item
plans to be out of the city for more than 4 weeks over the next 6 months
boolean
C0332197 (UMLS CUI [1,1])
C0008848 (UMLS CUI [1,2])
C0449238 (UMLS CUI [1,3])
C1301732 (UMLS CUI [1,4])
Other medical condition Significant | Chronic disease of respiratory system | Respiration Disorders Recurrent | Gastrointestinal Diseases | Neuromuscular Diseases | nervous system disorder | Mental disorders | Musculoskeletal Diseases Interferes with Exercise | Autoimmune Diseases | Collagen Diseases | Immunologic Deficiency Syndromes | HIV Seropositivity | Malignant Neoplasms | Skin carcinoma Controlled | Endocrine System Diseases | Metabolic Diseases | Other medical condition Life Threatening | Other medical condition Interferes with Exercise
Item
other significant medical conditions, including the following: chronic or recurrent respiratory, gastrointestinal, neuromuscular, neurological, or psychiatric conditions; musculoskeletal problems interfering with exercise; autoimmune or collagen vascular diseases; immunodeficiency diseases or a positive hiv test; malignancies within 5 years of study entry, with the exception of skin cancer that is therapeutically controlled; endocrine and metabolic disorders; or any other medical condition or disease that is life-threatening or that may interfere with or be aggravated by exercise
boolean
C3843040 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0264220 (UMLS CUI [2])
C0035204 (UMLS CUI [3,1])
C2945760 (UMLS CUI [3,2])
C0017178 (UMLS CUI [4])
C0027868 (UMLS CUI [5])
C0027765 (UMLS CUI [6])
C0004936 (UMLS CUI [7])
C0026857 (UMLS CUI [8,1])
C0521102 (UMLS CUI [8,2])
C0015259 (UMLS CUI [8,3])
C0004364 (UMLS CUI [9])
C0009326 (UMLS CUI [10])
C0021051 (UMLS CUI [11])
C0019699 (UMLS CUI [12])
C0006826 (UMLS CUI [13])
C0699893 (UMLS CUI [14,1])
C2911690 (UMLS CUI [14,2])
C0014130 (UMLS CUI [15])
C0025517 (UMLS CUI [16])
C3843040 (UMLS CUI [17,1])
C2826244 (UMLS CUI [17,2])
C3843040 (UMLS CUI [18,1])
C0521102 (UMLS CUI [18,2])
C0015259 (UMLS CUI [18,3])