Circulating Neoplastic Cells | White Blood Cell Count
Item
wbc < 50,000/mm^3 for patients with circulating tumor cells
boolean
C0027625 (UMLS CUI [1])
C0023508 (UMLS CUI [2])
Allergic Reaction bortezomib | Allergic Reaction alvocidib | Allergic Reaction Allopurinol | Allergic Reaction Sodium polystyrene sulfonate | Allergic Reaction Dexamethasone
Item
no prior allergic reaction to compounds of similar chemical or biological composition to and presumably able to tolerated bortezomib, flavopiridol, allopurinol, sodium polystyrene sulfonate, or dexamethasone
boolean
C1527304 (UMLS CUI [1,1])
C1176309 (UMLS CUI [1,2])
C1527304 (UMLS CUI [2,1])
C0281603 (UMLS CUI [2,2])
C1527304 (UMLS CUI [3,1])
C0002144 (UMLS CUI [3,2])
C1527304 (UMLS CUI [4,1])
C0142915 (UMLS CUI [4,2])
C1527304 (UMLS CUI [5,1])
C0011777 (UMLS CUI [5,2])
Neuropathy | CTCAE Grades
Item
no neuropathy >= grade 2
boolean
C0442874 (UMLS CUI [1])
C1516728 (UMLS CUI [2])
Condition Study Subject Participation Status Exclusion
Item
no other condition that would preclude study participation
boolean
C0348080 (UMLS CUI [1,1])
C2348568 (UMLS CUI [1,2])
C2828389 (UMLS CUI [1,3])
Pregnancy | Breast Feeding
Item
not pregnant or nursing
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
Fertility Contraceptive methods
Item
fertile patients must use effective contraception during and for 3 months after study participation
boolean
C0015895 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Transplantation of autologous hematopoietic stem cell
Item
prior autologous stem cell transplantation is allowed
boolean
C1831743 (UMLS CUI [1])
Allogeneic Stem Cell Transplantation
Item
no prior allogeneic stem cell transplantation
boolean
C2242529 (UMLS CUI [1])
Antineoplastic Agents
Item
no other concurrent anticancer agents
boolean
C0003392 (UMLS CUI [1])
Investigational New Drugs
Item
no other concurrent investigational agents
boolean
C0013230 (UMLS CUI [1])
Hemoglobin
Item
hemoglobin >= 8 g/dl
boolean
C0019046 (UMLS CUI [1])
Platelet Count measurement
Item
platelet count >= 100,000/mm^3
boolean
C0032181 (UMLS CUI [1])
Absolute neutrophil count
Item
absolute neutrophil count >= 1,500/mm^3
boolean
C0948762 (UMLS CUI [1])
Serum total bilirubin measurement
Item
bilirubin =< 2 times upper limit of normal (uln)
boolean
C1278039 (UMLS CUI [1])
Aspartate aminotransferase measurement | Alanine aminotransferase measurement
Item
ast/alt =< 3 times uln
boolean
C0201899 (UMLS CUI [1])
C0201836 (UMLS CUI [2])
Creatinine measurement, serum | Creatinine clearance measurement
Item
creatinine =< 2 times uln or creatinine clearance >= 50 ml/min
boolean
C0201976 (UMLS CUI [1])
C0373595 (UMLS CUI [2])