Sitting blood pressure mean
Item
mean sitting bp prior to randomization of 140-180/90-109 mmhg;
boolean
C0580946 (UMLS CUI [1,1])
C0444504 (UMLS CUI [1,2])
Renal Insufficiency Mild | Renal Insufficiency Moderate | Creatinine clearance measurement
Item
renal impairment prior to randomization of mild (50 ≤ clcr ≥ 80 ml/min) to moderate (30 ≤ clcr ≥50 ml/min) severity
boolean
C1565489 (UMLS CUI [1,1])
C2945599 (UMLS CUI [1,2])
C1565489 (UMLS CUI [2,1])
C0205081 (UMLS CUI [2,2])
C0373595 (UMLS CUI [3])
Malignant Hypertension | Sitting blood pressure
Item
malignant hypertension or sitting bp greater than 180/109 mmhg;
boolean
C0020540 (UMLS CUI [1])
C0580946 (UMLS CUI [2])
Heart failure Severe | Kidney Disease Severe
Item
severe heart failure, severe renal disease;
boolean
C0018801 (UMLS CUI [1,1])
C0205082 (UMLS CUI [1,2])
C0022658 (UMLS CUI [2,1])
C0205082 (UMLS CUI [2,2])
Myocardial Infarction | Cerebrovascular accident | Transient Ischemic Attack
Item
recent history of myocardial infarction, stroke or transient ischemic attack;
boolean
C0027051 (UMLS CUI [1])
C0038454 (UMLS CUI [2])
C0007787 (UMLS CUI [3])
Gastrointestinal Disease Significant Evidence of | Respiration Disorder | Hematological Disease | Metabolic Disease | Immune System Disease | Disease Interferes with Study Subject Participation Status
Item
history, clinical or current evidence of any significant gastrointestinal, respiratory, hematological, metabolic, immunological or any other underlying disease which in the opinion of the investigator would interfere with the patient's participation in the trial;
boolean
C0017178 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0332120 (UMLS CUI [1,3])
C0035204 (UMLS CUI [2])
C0018939 (UMLS CUI [3])
C0025517 (UMLS CUI [4])
C0021053 (UMLS CUI [5])
C0012634 (UMLS CUI [6,1])
C0521102 (UMLS CUI [6,2])
C2348568 (UMLS CUI [6,3])
Hypersensitivity Angiotensin II receptor antagonist | Medical contraindication Angiotensin II receptor antagonist | Hypersensitivity Angiotensin-Converting Enzyme Inhibitors | Medical contraindication Angiotensin-Converting Enzyme Inhibitors | Hypersensitivity Allergens Cross Reactive
Item
hypersensitivity or contraindications to arbs or ace inhibitors or any cross allergy;
boolean
C0020517 (UMLS CUI [1,1])
C0521942 (UMLS CUI [1,2])
C1301624 (UMLS CUI [2,1])
C0521942 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0003015 (UMLS CUI [3,2])
C1301624 (UMLS CUI [4,1])
C0003015 (UMLS CUI [4,2])
C0020517 (UMLS CUI [5,1])
C0002092 (UMLS CUI [5,2])
C0010357 (UMLS CUI [5,3])
Illicit Drugs
Item
treatment with dis-allowed medication;
boolean
C0086190 (UMLS CUI [1])
Pregnancy | Breast Feeding | Childbearing Potential Contraceptive methods Inadequate
Item
pregnant or breastfeeding females or females of childbearing potential without adequate contraception;
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
C3831118 (UMLS CUI [3,1])
C0700589 (UMLS CUI [3,2])
C0205412 (UMLS CUI [3,3])
Substance Use Disorders
Item
history of drug and/or alcohol abuse
boolean
C0038586 (UMLS CUI [1])