Study ID
Item
Study ID
integer
C2826693 (UMLS CUI [1])
Study site name
Item
Study site name
text
C2825164 (UMLS CUI [1])
Subject ID
Item
Subject ID
integer
C2348585 (UMLS CUI [1])
Date of MRI
Item
Date of MRI
date
C0011008 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
volume brain lesions
Item
1) Total volume of brain lesions on T2W image (cc):
float
C0449468 (UMLS CUI [1,1])
C0221505 (UMLS CUI [1,2])
Number of lesions volume
Item
2) Change in T2 lesion(s) volume (mL); a. Total number of T2 lesions:
float
C0449791 (UMLS CUI [1,1])
C0449468 (UMLS CUI [1,2])
Number of lesions regional
Item
3) Number of new or enlarging non-enhancing T2 lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
Number of lesions regional periventricular lesions
Item
i. Number of periventricular lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C3277690 (UMLS CUI [1,3])
Number of lesions regional juxtacortical lesions
Item
ii. Number of juxtacortical lesions:
integer
Number of lesions regional posterior fossa
Item
iii. Number of posterior fossa lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C1116439 (UMLS CUI [1,3])
Number of lesions regional cortical
Item
iv. Number of cortical lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C0007776 (UMLS CUI [1,3])
Number of lesions regional thalamus
Item
v. Number of thalamus lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C0039729 (UMLS CUI [1,3])
Number of lesions regional basal ganglia
Item
vi. Number of basal ganglia lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
C0004781 (UMLS CUI [1,3])
Number of lesions regional
Item
vii. Number of other lesions whose type is not specified:
integer
C0449791 (UMLS CUI [1,1])
C0205147 (UMLS CUI [1,2])
reference Technique
Item
4) Technique reference for new lesions (i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual. May also include visual observation, detection, etc.):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
Number of lesions Gd-enhancing lesions
Item
1) Total number of Gd-enhancing lesions:
integer
C0449791 (UMLS CUI [1,1])
C1333400 (UMLS CUI [1,2])
Gd-enhancing lesions new
Item
2) Number of NEW Gd-enhancing lesions:
integer
C1333400 (UMLS CUI [1,1])
C0205314 (UMLS CUI [1,2])
volume Gd-enhancing lesions
Item
3) Total volume of all Gd-enhancing lesions (cc):
float
C0449468 (UMLS CUI [1,1])
C1333400 (UMLS CUI [1,2])
volume Gd-enhancing lesions change
Item
4) Change in volume of all Gd-enhancing lesions (cc):
float
C0449468 (UMLS CUI [1,1])
C1333400 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
reference Technique
Item
5) Technique reference (i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
lesions Combined Unique Active
Item
1) Number of CUA lesions compared to previous time-point:
integer
C0221198 (UMLS CUI [1,1])
C0205195 (UMLS CUI [1,2])
C1710548 (UMLS CUI [1,3])
C0205177 (UMLS CUI [1,4])
reference Technique
Item
2) Technique reference for new lesions (i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual. May also include visual observation, detection, etc.):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
Number of lesions
Item
1) Total number of T1 hypointense lesions:
integer
C0449791 (UMLS CUI [1])
Number of lesions new
Item
2) Number of new T1 hypointense lesions:
integer
C0449791 (UMLS CUI [1,1])
C0205314 (UMLS CUI [1,2])
volume lesion
Item
3) Total volume of T1 hypointense lesions (mL):
float
C0449468 (UMLS CUI [1,1])
C0221198 (UMLS CUI [1,2])
volume lesion change
Item
4) Change in volume of T1 hypointense lesions (mL):
float
C0449468 (UMLS CUI [1,1])
C0221198 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
reference Technique
Item
5) Technique reference ( i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
brain volume change
Item
1) a. Change in brain volume (mL):
float
C1113695 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
brain volume change
Item
1) a. Change in brain volume (%):
float
C1113695 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
Volume fraction brain change
Item
2) a. Change in brain volume fraction (%):
float
C0560268 (UMLS CUI [1,1])
C0006104 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Ventricular volume change
Item
1) a. Change in ventricular volume (mL):
float
C1980012 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
Ventricular volume change
Item
1) a. Change in ventricular volume (%):
float
C1980012 (UMLS CUI [1,1])
C0392747 (UMLS CUI [1,2])
Volume fraction Ventricular change
Item
2) a. Change in ventricular volume fraction (ml):
float
C0560268 (UMLS CUI [1,1])
C0007799 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Volume fraction Ventricular change
Item
2) a. Change in ventricular volume fraction (%):
float
C0560268 (UMLS CUI [1,1])
C0007799 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
volume Gray matter change
Item
1) a. Change in gray matter volume
float
C0449468 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
volume fraction Gray matter change
Item
2) a. Change in gray matter volume fraction (%):
float
C0560268 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Number of lesion gray matter new
Item
1) Number of new gray matter lesions:
integer
C0449791 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
C0205314 (UMLS CUI [1,3])
Number of lesion gray matter
Item
2) Total number of gray matter lesions:
integer
C0449791 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
volume Gray matter
Item
3) Total volume of gray matter lesions (mL):
float
C0449468 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
volume Gray matter change
Item
4) Change in volume of gray matter lesions (mL):
float
C0449468 (UMLS CUI [1,1])
C0018220 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
reference Technique
Item
5) Technique reference for new lesions (i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual. May also include visual observation, detection, etc.):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
volume White matter change
Item
1) a. Change in white matter volume (%):
float
C0449468 (UMLS CUI [1,1])
C0682708 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
volume fraction White matter change
Item
2) a. Change in white matter volume fraction (%):
float
C0560268 (UMLS CUI [1,1])
C0682708 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
white matter appearance change
Item
3) Change in normal appearing white matter - complete as many times as needed (%):
float
C0682708 (UMLS CUI [1,1])
C0700364 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Timepoint
Item
a. Timepoint: [Add protocol-specific options]
time
C2348792 (UMLS CUI [1])
volume cerebral change
Item
1) a. Change in central cerebral volume (mL):
float
C0449468 (UMLS CUI [1,1])
C0006104 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Cortical thickness
Item
2) a. Change in cortical thickness (mm):
float
volume Hippocampus change
Item
3) Brain structure volumes i) Change in hippocampus (mL):
float
C0449468 (UMLS CUI [1,1])
C0019564 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
volume Thalamus change
Item
i. Change in thalamus (mL):
float
C0449468 (UMLS CUI [1,1])
C0039729 (UMLS CUI [1,2])
C0392747 (UMLS CUI [1,3])
Number of lesion spinal cord lesions
Item
1) Total number of spinal cord lesions:
integer
C0449791 (UMLS CUI [1,1])
C0241224 (UMLS CUI [1,2])
region Spinal cord lesion
Item
2) Spinal cord lesion region (mention all that apply: C1-C7 ; T1-T12; L1-L5 ):
text
C1515974 (UMLS CUI [1,1])
C0241224 (UMLS CUI [1,2])
location Spinal cord lesions
Item
3) Spinal cord lesions location (mention all that apply: Anterior; Posterior; Lateral ):
text
C0450429 (UMLS CUI [1,1])
C0241224 (UMLS CUI [1,2])
area Spinal cord
Item
4) Spinal cord area
float
C2586162 (UMLS CUI [1,1])
C0037925 (UMLS CUI [1,2])
Volume Spinal cord
Item
4) Spinal cord Volume
float
C2700258 (UMLS CUI [1,1])
C0037925 (UMLS CUI [1,2])
reference Technique
Item
5) Technique reference (i.e. literature citation(s), MRI Acquisition Manual or Analysis Manual):
text
C0034925 (UMLS CUI [1,1])
C0449851 (UMLS CUI [1,2])
MTR Mean
Item
Mean MTR unit
text
C2584640 (UMLS CUI [1,1])
C0456603 (UMLS CUI [1,2])
C0444504 (UMLS CUI [1,3])
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
MTR histogram peak position
Item
MTR histogram peak position unit
text
C2584640 (UMLS CUI [1,1])
C0456603 (UMLS CUI [1,2])
C2348974 (UMLS CUI [1,3])
C0444505 (UMLS CUI [1,4])
C0733755 (UMLS CUI [1,5])
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
MTR histogram peak height
Item
MTR histogram peak height unit
text
C2584640 (UMLS CUI [1,1])
C0456603 (UMLS CUI [1,2])
C2348974 (UMLS CUI [1,3])
C0444505 (UMLS CUI [1,4])
C0489786 (UMLS CUI [1,5])
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Mean FA unit
Item
Mean FA unit
text
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Mean ADC unit
Item
Mean ADC unit
text
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Mean axial diffusivity unit
Item
Mean axial diffusivity unit
text
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
Mean radial diffusivity unit
Item
Mean radial diffusivity unit
text
brain
Item
Whole brain
text
C0006104 (UMLS CUI [1])
WM Normal Appearing
Item
Normal Appearing WM
text
C0682708 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])
GM Normal Appearing
Item
Normal Appearing GM
text
C0018220 (UMLS CUI [1,1])
C0205307 (UMLS CUI [1,2])