Age
Item
age 18-65
boolean
C0001779 (UMLS CUI [1])
Major depressive disorder
Item
primary diagnosis of major depressive disorder (mdd)
boolean
C1269683 (UMLS CUI [1])
Antidepressant therapy
Item
completion of at least 8-12 weeks (and no longer than 6 months) of treatment with escitalopram, citalopram, or sertraline, with at least 6 weeks at an adequate dose (i.e., 20 mg escitalopram; 40 mg citalopram; 150 mg sertraline)
boolean
C1099456 (UMLS CUI [1])
C0008845 (UMLS CUI [2])
C0074393 (UMLS CUI [3])
Hamilton rating scale for depression
Item
hamilton rating scale for depression, 17-item (hrsd17) score less than or equal to 14 and/or clinical global impression - severity (cgi-s) score less than or equal to 3
boolean
C0451203 (UMLS CUI [1])
Difficulties with cognition and/or concentration
Item
self-reported difficulties with cognition and/or concentration, and an inventory for depressive symptomatology clinician-rated, 30-item (ids-c30) item #16 (concentration and decision making) score less than or equal to 2
boolean
C0009240 (UMLS CUI [1])
C0424098 (UMLS CUI [2])
Language
Item
ability to read and write in english (required because instructions for cognitive testing and several questionnaires are available only in english)
boolean
C1145677 (UMLS CUI [1])
Comorbidity
Item
presence of untreated or unstable comorbid medical condition based on physician information or evidence at examination, such as hypertension, diabetes, hypothyroidism.
boolean
C0009488 (UMLS CUI [1])
Cardiovascular disease or seizure disorder
Item
presence of known cardiovascular disease or seizure disorder.
boolean
C0007222 (UMLS CUI [1])
C0014544 (UMLS CUI [2])
Other primary psychiatric disorders or conditions
Item
presence of other primary psychiatric disorders or conditions (including depression due to medical conditions, currently suicidal or high suicide risk, current or past psychotic disorders of any type, bipolar disorder (i, ii, or not otherwise specified [nos]), schizophrenia, schizoaffective disorder, anorexia, bulimia, obsessive compulsive disorder, alcohol or substance abuse or dependence within the last 6 months)
boolean
C0004936 (UMLS CUI [1])
C0520618 (UMLS CUI [2])
C0438696 (UMLS CUI [3])
C0033975 (UMLS CUI [4])
C0005586 (UMLS CUI [5])
C0036341 (UMLS CUI [6])
C0036337 (UMLS CUI [7])
C0003125 (UMLS CUI [8])
C0006370 (UMLS CUI [9])
C0028768 (UMLS CUI [10])
organic brain injury or dementia
Item
presence of organic brain injury or dementia, based on a cutoff score of < 20 on the mini mental status examination (mmse).
boolean
C0270611 (UMLS CUI [1])
C0497327 (UMLS CUI [2,1])
C0451306 (UMLS CUI [2,2])
Concomitant pharmacological or psychotherapeutic treatment
Item
concomitant pharmacological or psychotherapeutic treatment (in addition to one ssri as described in inclusion criteria) including but not limited to anxiolytics, neuroleptics, mood stabilizers
boolean
C1707479 (UMLS CUI [1])
Hospitalization for mental illness
Item
Hospitalization for mental illness within the past year.
boolean
C0019993 (UMLS CUI [1,1])
C0004936 (UMLS CUI [1,2])
pregnant or planning to become pregnant
Item
for women, currently pregnant or planning to become pregnant in the next year.
boolean
C0032961 (UMLS CUI [1])
C2081645 (UMLS CUI [2])