Symptomatic congestive heart failure chronic | New York Heart Association Classification
Item
chronic symptomatic nyha class ii or iii chf for at least 90 days before the study
boolean
C0742758 (UMLS CUI [1,1])
C0205191 (UMLS CUI [1,2])
C1275491 (UMLS CUI [2])
Left ventricular systolic dysfunction Evidence of | Left ventricular ejection fraction | Cardiac ventriculography | Radionuclide Ventriculography | Echocardiography
Item
left ventricular systolic dysfunction as evidenced by left ventricular ejection fraction < 40%, measured using contrast or radionuclide ventriculography or by echocardiography, within 180 days of the study start
boolean
C1277187 (UMLS CUI [1,1])
C0332120 (UMLS CUI [1,2])
C0428772 (UMLS CUI [2])
C0596683 (UMLS CUI [3])
C0034610 (UMLS CUI [4])
C0013516 (UMLS CUI [5])
Serum potassium measurement
Item
serum potassium > 3.5 meq/l.
boolean
C0302353 (UMLS CUI [1])
Furosemide Daily Oral chronic Patient need for
Item
chronic oral daily requirement of 80-240 mg of furosemide for at least 7 days before the study start
boolean
C0016860 (UMLS CUI [1,1])
C0332173 (UMLS CUI [1,2])
C1527415 (UMLS CUI [1,3])
C0205191 (UMLS CUI [1,4])
C0686904 (UMLS CUI [1,5])
Congestive heart failure Therapeutic procedure Stable | Angiotensin-Converting Enzyme Inhibitors | Angiotensin II receptor antagonist | Adrenergic beta-Antagonists
Item
receiving a stable medical regimen for chf for at least 60 days before the study start, including angiotensin converting enzyme inhibitors (acei) or angiotensin receptor blockers (arbs), and/or beta-blockers.
boolean
C0018802 (UMLS CUI [1,1])
C0087111 (UMLS CUI [1,2])
C0205360 (UMLS CUI [1,3])
C0003015 (UMLS CUI [2])
C0521942 (UMLS CUI [3])
C0001645 (UMLS CUI [4])
Disease Unstable Clinical | Diuretic therapy Discontinuation At risk patient safety
Item
clinical instability such that withholding diuretic therapy would be unsafe
boolean
C0012634 (UMLS CUI [1,1])
C0443343 (UMLS CUI [1,2])
C0205210 (UMLS CUI [1,3])
C0948575 (UMLS CUI [2,1])
C1444662 (UMLS CUI [2,2])
C1444641 (UMLS CUI [2,3])
C1113679 (UMLS CUI [2,4])
Renal Insufficiency Significant | Estimation of creatinine clearance by Cockcroft-Gault formula | Renal alteration | RENAL FAILURE INTRINSIC
Item
significant renal impairment (e.g., creatinine clearance < 45 ml/min by the cockcroft-gault formula), or changing renal function during the 7 days before study start, or intrinsic renal disease
boolean
C1565489 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C2711451 (UMLS CUI [2])
C0184571 (UMLS CUI [3])
C0748306 (UMLS CUI [4])
Systolic Pressure
Item
systolic blood pressure (sbp) consistently < 90 mm hg
boolean
C0871470 (UMLS CUI [1])
Myocardial Infarction | Angina, Unstable | Myocardial Ischemia Evidence Clinical
Item
myocardial infarction within 90 days of study start, unstable angina within 14 days of study start, or any clinical evidence of active myocardial ischemia
boolean
C0027051 (UMLS CUI [1])
C0002965 (UMLS CUI [2])
C0151744 (UMLS CUI [3,1])
C3887511 (UMLS CUI [3,2])
C0205210 (UMLS CUI [3,3])
Percutaneous Coronary Intervention | Cardiac Surgery procedures
Item
percutaneous coronary intervention or cardiac surgery within 90 days of study start
boolean
C1532338 (UMLS CUI [1])
C0018821 (UMLS CUI [2])
Restrictive cardiomyopathy | Hypertrophic Cardiomyopathy | Pericarditis, Constrictive | Cardiac Tamponade
Item
restrictive or obstructive cardiomyopathy, constrictive pericarditis, pericardial tamponade, other conditions in which cardiac output was dependent on venous return, or for subjects expected to have low filling pressures
boolean
C0007196 (UMLS CUI [1])
C0007194 (UMLS CUI [2])
C0031048 (UMLS CUI [3])
C0007177 (UMLS CUI [4])
Allograft heart | Allograft kidney
Item
prior cardiac or renal allografts
boolean
C0564471 (UMLS CUI [1])
C0564454 (UMLS CUI [2])