Non-Small Cell Lung Carcinoma
Item
diagnosis of nsclc
boolean
C0007131 (UMLS CUI [1])
Locally Advanced Malignant Neoplasm | Metastatic Neoplasm | TNM clinical staging
Item
locally advanced or metastatic disease (stage iiib or iv).
boolean
C0677984 (UMLS CUI [1])
C2939420 (UMLS CUI [2])
C3258246 (UMLS CUI [3])
Chemotherapy Palliative procedure Locally Advanced Malignant Neoplasm | Chemotherapy Palliative procedure Metastatic Neoplasm
Item
patients must have previously received one chemotherapy regimen for palliative therapy of locally advanced or metastatic disease.
boolean
C0392920 (UMLS CUI [1,1])
C1285158 (UMLS CUI [1,2])
C0677984 (UMLS CUI [1,3])
C0392920 (UMLS CUI [2,1])
C1285158 (UMLS CUI [2,2])
C2939420 (UMLS CUI [2,3])
Measurable Disease
Item
disease status must be that of measurable disease as defined by recist criteria
boolean
C1513041 (UMLS CUI [1])
ECOG performance status | organ function
Item
performance status of 0 to 1 on the eastern cooperative oncology group (ecog) scale; and adequate organ function.
boolean
C1520224 (UMLS CUI [1])
C0678852 (UMLS CUI [2])
Metastatic malignant neoplasm to brain | Second Primary Cancer
Item
known or suspected brain metastasis, or second primary malignancy that is clinically detectable at the time of consideration for study enrollment
boolean
C0220650 (UMLS CUI [1])
C0751623 (UMLS CUI [2])
cancer treatment
Item
concurrent administration of any other tumor therapy.
boolean
C0920425 (UMLS CUI [1])
nervous system disorder Significant | Mental disorders Significant | Seizures | Dementia | Comorbidity Serious Affecting patient safety | Comorbidity Serious Compliance behavior Limited
Item
history of significant neurological or mental disorder, including seizures or dementia; or any other serious concomitant disorders that would compromise the safety of the patient or compromise the patient's ability to complete the study
boolean
C0027765 (UMLS CUI [1,1])
C0750502 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C0750502 (UMLS CUI [2,2])
C0036572 (UMLS CUI [3])
C0497327 (UMLS CUI [4])
C0009488 (UMLS CUI [5,1])
C0205404 (UMLS CUI [5,2])
C0392760 (UMLS CUI [5,3])
C1113679 (UMLS CUI [5,4])
C0009488 (UMLS CUI [6,1])
C0205404 (UMLS CUI [6,2])
C1321605 (UMLS CUI [6,3])
C0439801 (UMLS CUI [6,4])
Aspirin Interrupt Unable | Anti-Inflammatory Agents, Non-Steroidal Interrupt Unable | pemetrexed Dose
Item
inability to interrupt aspirin or other nonsteroidal anti-inflammatory drugs (nsaids) 2 days before, the day of, and 2 days after the dose of pemetrexed.
boolean
C0004057 (UMLS CUI [1,1])
C0443239 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C0003211 (UMLS CUI [2,1])
C0443239 (UMLS CUI [2,2])
C1299582 (UMLS CUI [2,3])
C0210657 (UMLS CUI [3,1])
C0178602 (UMLS CUI [3,2])
Folic Acid Intake Unwilling | Vitamin B12 supplement Intake Unwilling | Dexamethasone Intake Unwilling
Item
inability or unwillingness to take folic acid, vitamin b12 supplementation, or dexamethasone
boolean
C0016410 (UMLS CUI [1,1])
C1512806 (UMLS CUI [1,2])
C0558080 (UMLS CUI [1,3])
C3661610 (UMLS CUI [2,1])
C1512806 (UMLS CUI [2,2])
C0558080 (UMLS CUI [2,3])
C0011777 (UMLS CUI [3,1])
C1512806 (UMLS CUI [3,2])
C0558080 (UMLS CUI [3,3])