not pregnant, age
Item
non-pregnant females =/> 18 years of age
boolean
C0232973 (UMLS CUI [1])
C0001779 (UMLS CUI [2])
non-inflammatory breast cancer stage iia - iiic or high risk node negative
Item
non-inflammatory breast cancer stage iia - iiic or high risk node negative
boolean
C0006142 (UMLS CUI [1,1])
C0442743 (UMLS CUI [1,2])
C2216702 (UMLS CUI [2])
C3160889 (UMLS CUI [3])
invasive cancer and documented er/pgr receptor status
Item
core biopsy of breast demonstrating invasive cancer and documented er/pgr receptor status
boolean
C0842740 (UMLS CUI [1,1])
C0853879 (UMLS CUI [1,2])
C2021584 (UMLS CUI [2])
C2239069 (UMLS CUI [3])
cardiac and hematologic function
Item
normal cardiac function and adequate hematologic function
boolean
C0232164 (UMLS CUI [1])
C0221130 (UMLS CUI [2])
her2 positive
Item
human epidermal growth factor receptor 2 protein (her2) positive
boolean
C1960398 (UMLS CUI [1])
metastatic disease
Item
no evidence of metastatic disease
boolean
C2939420 (UMLS CUI [1])
ecog performance status
Item
ecog performance status 0 - 1
boolean
C1520224 (UMLS CUI [1])
contraception
Item
women of childbearing potential must agree to using effective contraception while on treatment and for at least 3 months post-treatment
boolean
C3831118 (UMLS CUI [1])
C0700589 (UMLS CUI [2])
investigational drug application
Item
treated with other investigational drugs within 30 days
boolean
C0162778 (UMLS CUI [1])
intercurrent disease or infection
Item
uncontrolled intercurrent disease or active infection
boolean
C0277557 (UMLS CUI [1])
C0240021 (UMLS CUI [2])
sensitivity to e. coli-derived proteins or polysorbate 80
Item
known sensitivity to e. coli-derived proteins or polysorbate 80
boolean
C0332324 (UMLS CUI [1,1])
C0014834 (UMLS CUI [1,2])
C0004627 (UMLS CUI [1,3])
C0332324 (UMLS CUI [2,1])
C0032601 (UMLS CUI [2,2])
psychiatric illness or social situation that would limit study compliance
Item
psychiatric illness or social situation that would limit study compliance
boolean
C0004936 (UMLS CUI [1])
C0748872 (UMLS CUI [2])
C1321605 (UMLS CUI [3])
peripheral neuropathy
Item
pre-existing peripheral neuropathy > grade 1
boolean
C0031117 (UMLS CUI [1])
cancer within 5 years of screening with the exception of surgically cured nonmelanomatous skin cancer; in-situ carcinoma of the cervix; or in-situ carcinoma of the breast
Item
cancer within 5 years of screening with the exception of surgically cured nonmelanomatous skin cancer; in-situ carcinoma of the cervix; or in-situ carcinoma of the breast
boolean
C1882062 (UMLS CUI [1])
C0009488 (UMLS CUI [2])
bilateral breast cancer
Item
bilateral synchronous breast cancer
boolean
C0281267 (UMLS CUI [1])
inflammatory breast cancer
Item
inflammatory breast cancer
boolean
C0278601 (UMLS CUI [1])
pregnant or breast feeding
Item
women who are pregnant or breast feeding
boolean
C0549206 (UMLS CUI [1])
C1623040 (UMLS CUI [2])