Breast adenocarcinoma | TNM clinical staging | Primary tumor size | Lymph nodes Axillary Palpable Clinical
Item
histologically confirmed adenocarcinoma of the breast w/ stage ii-iii disease w/ a primary tumor >/=2cm or clinically palpable axillary lymph nodes.
boolean
C0858252 (UMLS CUI [1])
C3258246 (UMLS CUI [2])
C1302656 (UMLS CUI [3])
C0024204 (UMLS CUI [4,1])
C0004454 (UMLS CUI [4,2])
C0522499 (UMLS CUI [4,3])
C0205210 (UMLS CUI [4,4])
Core biopsy Pretreatment | Incisional biopsy | Tissue Adequate Histology Procedure
Item
pre-treatment core or incisional bx w/ adequate tissue for histology &
boolean
C1318309 (UMLS CUI [1,1])
C3539076 (UMLS CUI [1,2])
C0184922 (UMLS CUI [2])
C0040300 (UMLS CUI [3,1])
C0205411 (UMLS CUI [3,2])
C0344441 (UMLS CUI [3,3])
Genome Analysis | Proteome Analysis
Item
genomic/proteomic analysis.
boolean
C0017428 (UMLS CUI [1,1])
C0936012 (UMLS CUI [1,2])
C0751973 (UMLS CUI [2,1])
C0936012 (UMLS CUI [2,2])
primary tumor Measurable 2-Dimensional | Physical Examination | Diagnostic Imaging Female breast
Item
primary tumor must be bi-dimensionally measurable by physical exam or dx breast imaging. measurements must be obtained w/in 3 wks prior to study entry.
boolean
C0677930 (UMLS CUI [1,1])
C1513040 (UMLS CUI [1,2])
C1705052 (UMLS CUI [1,3])
C0031809 (UMLS CUI [2])
C0011923 (UMLS CUI [3,1])
C0222603 (UMLS CUI [3,2])
organ function | Absolute neutrophil count | Hemoglobin | Blood Platelets | Creatinine measurement, serum | Creatinine clearance measurement | Bilirubin, total measurement | Liver Function Tests
Item
adequate organ fxn:agc>1500; hb>/=9.0;plts>/=100k; crt</=2.0;cacl crt clr>/=50; total bili</=uln; lfts<2.0 uln
boolean
C0678852 (UMLS CUI [1])
C0948762 (UMLS CUI [2])
C0019046 (UMLS CUI [3])
C0005821 (UMLS CUI [4])
C0201976 (UMLS CUI [5])
C0373595 (UMLS CUI [6])
C0201913 (UMLS CUI [7])
C0023901 (UMLS CUI [8])
ECOG performance status
Item
ecog performance status 0-1
boolean
C1520224 (UMLS CUI [1])
Pregnancy test negative
Item
neg. pregnancy test
boolean
C0427780 (UMLS CUI [1])
Operative Surgical Procedures Primary Definitive
Item
pts may not have had definitive primary surgery.
boolean
C0543467 (UMLS CUI [1,1])
C0205225 (UMLS CUI [1,2])
C0443196 (UMLS CUI [1,3])
Carcinoma breast stage IV
Item
metastatic breast cancer
boolean
C0278488 (UMLS CUI [1])
Prior Chemotherapy Breast Carcinoma | Prior Hormone Therapy Breast Carcinoma
Item
any prior chemo or hormonal therapy for breast cancer
boolean
C1514457 (UMLS CUI [1,1])
C0678222 (UMLS CUI [1,2])
C1514460 (UMLS CUI [2,1])
C0678222 (UMLS CUI [2,2])
Malignant Neoplasms
Item
prior history of malignancy w/in the previous 5 yrs.
boolean
C0006826 (UMLS CUI [1])
Communicable Disease physiologic resolution
Item
no active unresolved infection
boolean
C0009450 (UMLS CUI [1,1])
C1514893 (UMLS CUI [1,2])
major surgery
Item
no major surgery w/in 2wks of start of study
boolean
C0679637 (UMLS CUI [1])