breast cancer
Item
measurable stage iv or inoperable stage iii advanced breast cancer.
boolean
C0678222 (UMLS CUI [1])
prior therapies
Item
there is no limit on the number of prior therapies.
boolean
C1514463 (UMLS CUI [1])
chemotherapy
Item
at least 3 weeks since prior chemotherapy, biological or hormonal therapy
boolean
C0392920 (UMLS CUI [1])
surgical biopsy
Item
at least 2 weeks since surgical biopsy
boolean
C0005558 (UMLS CUI [1])
major surgery
Item
at least 3 weeks since major (open thoracic/abdominal/cardiac) surgery.
boolean
C0679637 (UMLS CUI [1])
central nervous system (cns) metastases
Item
no central nervous system (cns) metastases except solitary brain metastasis
boolean
C0279130 (UMLS CUI [1])
cardiac dysfunction
Item
no cardiac dysfunction
boolean
C3277906 (UMLS CUI [1])
left ventricular ejection fraction
Item
left ventricular ejection fraction (lvef) ≥ 50% as determined by multiple gated acquisition scan (muga)/echocardiogram
boolean
C0428772 (UMLS CUI [1])
blood count
Item
adequate blood counts
boolean
C0005771 (UMLS CUI [1])
normal liver and kidney function
Item
normal liver and kidney function
boolean
C1848676 (UMLS CUI [1])
C0232805 (UMLS CUI [2])
negative serum pregnancy test
Item
negative serum pregnancy test.
boolean
C0430061 (UMLS CUI [1])
informed consent
Item
able to provide informed consent
boolean
C0021430 (UMLS CUI [1])
pregnant or breast feeding
Item
pregnant or breast feeding.
boolean
C0549206 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
dasatinib
Item
prior treatment with dasatinib.
boolean
C1455147 (UMLS CUI [1])
bone disease
Item
bone as the only site of disease.
boolean
C0005940 (UMLS CUI [1])
gastrointestinal bleeding
Item
significant gastrointestinal bleeding
boolean
C0017181 (UMLS CUI [1])
septicemia, acute hepatitis
Item
septicemia, infection, acute hepatitis, hypokalemia, or hypomagnesemia
boolean
C0036690 (UMLS CUI [1])
C0267797 (UMLS CUI [2])