Informed consent
Item
patient is willing to sign study specific informed consent
boolean
C0021430 (UMLS CUI [1])
Squamous cell carcinoma | Papillary squamous cell carcinoma | Basaloid squamous cell carcinoma
Item
pathologically proven (histologically or cytologically) diagnosis of squamous cell carcinoma (including histological variants like papillary squamous cell carcinoma and basaloid squamous cell carcinoma)
boolean
C0007137 (UMLS CUI [1])
C0334244 (UMLS CUI [2])
C1266005 (UMLS CUI [3])
Squamous cell carcinoma of mouth Advanced | TNM clinical staging | Tongue | Sublingual Region | Hard Palate | Gingiva | Buccal mucosa | Structure of retromolar area of mouth | Head and Neck Neoplasms | Oropharyngeal | Tumor of ear, nose and throat | Therapeutic radiology procedure
Item
advanced stage but not metastatic scc of the oral cavity (iii or iva, b); sites in the oral cavity include oral tongue, floor of mouth, hard palate, gingiva, buccal mucosa, retromolar trigone; often, head & neck tumors may involve other adjacent sites, such as the oropharynx- in these cases, the criteria is that the tumor must appear to have originated in the oral cavity per ear, nose, and throat (ent)/radiation oncology
boolean
C0585362 (UMLS CUI [1,1])
C0205179 (UMLS CUI [1,2])
C3258246 (UMLS CUI [2])
C0040408 (UMLS CUI [3])
C0026638 (UMLS CUI [4])
C0226901 (UMLS CUI [5])
C0017562 (UMLS CUI [6])
C1578559 (UMLS CUI [7])
C0226920 (UMLS CUI [8])
C0018671 (UMLS CUI [9])
C0521367 (UMLS CUI [10])
C0345616 (UMLS CUI [11])
C1522449 (UMLS CUI [12])
Indication Ear, nose and throat surgery
Item
patient is deemed to be a surgical candidate by ent
boolean
C3146298 (UMLS CUI [1,1])
C1274038 (UMLS CUI [1,2])
Karnofsky Performance Status
Item
karnofsky performance status (kps) 0-2
boolean
C0206065 (UMLS CUI [1])
Childbearing Potential Serum pregnancy test negative | Therapeutic radiology procedure
Item
for women of childbearing potential, a negative serum pregnancy test completed prior to any radiation therapy
boolean
C3831118 (UMLS CUI [1,1])
C0430061 (UMLS CUI [1,2])
C1522449 (UMLS CUI [2])
HIV Infections | CD4 Count determination procedure | Viral load measurement | Antiretroviral Therapy, Highly Active
Item
patients with human immunodeficiency virus (hiv) infection are not automatically excluded, but must meet the following criteria: cluster of differentiation 4 (cd4) count is > 499/cu mm and their viral load is < 50 copies/ml; use of highly active antiretroviral therapy (haart) is allowed
boolean
C0019693 (UMLS CUI [1])
C0243009 (UMLS CUI [2])
C1261478 (UMLS CUI [3])
C0887947 (UMLS CUI [4])
invasive cancer Previous Free of | Skin carcinoma
Item
patient is free of any prior invasive malignancy (except non-melanomatous skin cancer) for a minimum of the past 3 years
boolean
C0677898 (UMLS CUI [1,1])
C0205156 (UMLS CUI [1,2])
C0332296 (UMLS CUI [1,3])
C0699893 (UMLS CUI [2])
Metastatic Neoplasm outside Neck | Metastatic Neoplasm outside Supraclavicular region of neck | PET/CT scan | Biopsy
Item
metastatic disease beyond the neck or supraclavicular area as demonstrated by positron emission tomography (pet)/ct or biopsy
boolean
C2939420 (UMLS CUI [1,1])
C0205101 (UMLS CUI [1,2])
C0027530 (UMLS CUI [1,3])
C2939420 (UMLS CUI [2,1])
C0205101 (UMLS CUI [2,2])
C0230078 (UMLS CUI [2,3])
C1699633 (UMLS CUI [3])
C0005558 (UMLS CUI [4])
Karnofsky Performance Status
Item
kps 3 or worse
boolean
C0206065 (UMLS CUI [1])
Malignant tumor of parapharyngeal space | Neoplasm of retropharyngeal lymph nodes | X-Ray Computed Tomography | PET/CT scan
Item
gross disease in the retrostyloid (high level ii) or retropharyngeal lymph node regions by ct or pet/ct
boolean
C0345756 (UMLS CUI [1])
C1264204 (UMLS CUI [2])
C0040405 (UMLS CUI [3])
C1699633 (UMLS CUI [4])
Squamous cell carcinoma of the head and neck | Prior Therapy Absent | Chemotherapy Regimen | Therapeutic radiology procedure | Operative Surgical Procedures outside Biopsy
Item
patients may not have received previous therapy for their head and neck scc, including chemotherapy, radiation therapy, or surgery beyond biopsy
boolean
C1168401 (UMLS CUI [1])
C1514463 (UMLS CUI [2,1])
C0332197 (UMLS CUI [2,2])
C0392920 (UMLS CUI [3])
C1522449 (UMLS CUI [4])
C0543467 (UMLS CUI [5,1])
C0205101 (UMLS CUI [5,2])
C0005558 (UMLS CUI [5,3])
Second Primary Cancer | Therapeutic procedure | Disease Free of | Carcinoma in Situ | Carcinoma in situ of uterine cervix | Skin carcinoma
Item
second primary malignancy; exceptions are 1) patient had a second primary malignancy but has been treated and disease free for at least 3 years, 2) in situ carcinoma (e.g. in situ carcinoma of the cervix), 3) non-melanomatous carcinoma of the skin
boolean
C0751623 (UMLS CUI [1])
C0087111 (UMLS CUI [2])
C0012634 (UMLS CUI [3,1])
C0332296 (UMLS CUI [3,2])
C0007099 (UMLS CUI [4])
C0851140 (UMLS CUI [5])
C0699893 (UMLS CUI [6])
Systemic disease Simultaneous Serious At risk patient safety | Systemic disease Simultaneous Serious Compliance behavior Limited | Communicable Diseases At risk patient safety | Communicable Diseases Compliance behavior Limited
Item
serious concomitant systemic disorders (including active infections) that would compromise the safety of the patient or compromise the patient's ability to complete the study, at the discretion of the investigator; this includes scleroderma
boolean
C0442893 (UMLS CUI [1,1])
C0521115 (UMLS CUI [1,2])
C0205404 (UMLS CUI [1,3])
C1444641 (UMLS CUI [1,4])
C1113679 (UMLS CUI [1,5])
C0442893 (UMLS CUI [2,1])
C0521115 (UMLS CUI [2,2])
C0205404 (UMLS CUI [2,3])
C1321605 (UMLS CUI [2,4])
C0439801 (UMLS CUI [2,5])
C0009450 (UMLS CUI [3,1])
C1444641 (UMLS CUI [3,2])
C1113679 (UMLS CUI [3,3])
C0009450 (UMLS CUI [4,1])
C1321605 (UMLS CUI [4,2])
C0439801 (UMLS CUI [4,3])
Pregnancy | Childbearing Potential Age Urine pregnancy test | Childbearing Potential Age Contraceptive methods | Hormonal contraception | Contraception, Barrier | Sexual Abstinence
Item
women who are pregnant; women of childbearing age must agree to undergo a urine pregnancy test prior to therapy and to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation and for 6 months after; should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately
boolean
C0032961 (UMLS CUI [1])
C3831118 (UMLS CUI [2,1])
C0001779 (UMLS CUI [2,2])
C0430056 (UMLS CUI [2,3])
C3831118 (UMLS CUI [3,1])
C0001779 (UMLS CUI [3,2])
C0700589 (UMLS CUI [3,3])
C2985296 (UMLS CUI [4])
C0004764 (UMLS CUI [5])
C0036899 (UMLS CUI [6])
Medical contraindication Ear, nose and throat surgery
Item
patient is deemed to not be a surgical candidate by ent
boolean
C1301624 (UMLS CUI [1,1])
C1274038 (UMLS CUI [1,2])