noncardiac surgery
Item
patients undergoing noncardiac surgery
boolean
C0543467 (UMLS CUI [1,1])
C1522601 (UMLS CUI [1,2])
C1518422 (UMLS CUI [1,3])
age
Item
≥ 45 years of age; either sex.
boolean
C0001779 (UMLS CUI [1])
in-patient duration
Item
have an expected length of stay ≥ 24 hours
boolean
C0023303 (UMLS CUI [1])
ID.4
Item
fulfill any one of the following 6 criteria:
boolean
coronary artery disease
Item
coronary artery disease;
boolean
C1956346 (UMLS CUI [1])
peripheral vascular disease
Item
peripheral vascular disease;
boolean
C0085096 (UMLS CUI [1])
history of stroke
Item
history of stroke due to atherothrombotic disease;
boolean
C4039739 (UMLS CUI [1])
congestive heart failure
Item
hospitalization for congestive heart failure within 3 years of randomization;
boolean
C0019993 (UMLS CUI [1,1])
C0018802 (UMLS CUI [1,2])
major vascular surgery
Item
undergoing major vascular surgery; or
boolean
C0042381 (UMLS CUI [1])
informed consent; comorbidities
Item
any 3 of the following 7 criteria: scheduled for high risk surgery (i.e. intraperitoneal or intrathoracic); emergency/urgent surgery; any history of congestive heart failure; history of a transient ischemic attack (tia); diabetes and currently on an oral hypoglycemic agent or insulin therapy; preoperative serum creatinine > 175 µmol/l (> 2.0 mg/dl); or age > 70 years.
boolean
C2216322 (UMLS CUI [1])
C0018802 (UMLS CUI [2,1])
C0262926 (UMLS CUI [2,2])
C0007787 (UMLS CUI [3,1])
C0262926 (UMLS CUI [3,2])
C0011849 (UMLS CUI [4,1])
C0020616 (UMLS CUI [4,2])
C0557978 (UMLS CUI [4,3])
C0201976 (UMLS CUI [5,1])
C0445204 (UMLS CUI [5,2])
contraindication to metoprolol
Item
contraindication to metoprolol including any of the following: significant bradycardia (heart rate < 50 beats per minute); second or third degree heart block without a pacemaker; asthma that has been active within the last decade; and history of chronic obstructive pulmonary disease (copd) with bronchospasm on pulmonary function tests.
boolean
C0428977 (UMLS CUI [1])
C0264906 (UMLS CUI [2])
C0151517 (UMLS CUI [3])
C0004096 (UMLS CUI [4])
C0024117 (UMLS CUI [5])
beta-blocker usage
Item
clinical plan to use a beta-blocker preoperatively or during the first 30 postoperative days
boolean
C0001645 (UMLS CUI [1])
hypersensitivity to beta-blocker
Item
prior adverse reaction to a beta-blocker
boolean
C0020517 (UMLS CUI [1,1])
C0001645 (UMLS CUI [1,2])
cabg
Item
coronary artery bypass graft (cabg) surgery with complete revascularization in the preceding 5 years and no evidence of cardiac ischemia since the cabg surgery
boolean
C0010055 (UMLS CUI [1,1])
C0151744 (UMLS CUI [1,2])
C0332197 (UMLS CUI [1,3])
low risk surgery
Item
patients undergoing low risk surgical procedures (potential examples include transurethral procedures [transurethral prostatectomies (turps), stone baskets, etc.], ophthalmologic procedures under topical or regional anesthesia [cornea transplants, cataract surgery, etc.], and surgeries with limited physiological stresses [digital re-implantation, nerve repairs, etc.] )
boolean
C0543467 (UMLS CUI [1,1])
C3538919 (UMLS CUI [1,2])
concurrent use of verapamil
Item
concurrent use of verapamil
boolean
C0009429 (UMLS CUI [1,1])
C0042523 (UMLS CUI [1,2])
prior enrollment in this trial
Item
prior enrollment in this trial
boolean
C1516879 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])