diagnosis of NSCLC
Item
histologic or cytologic diagnosis of non-small cell lung carcinoma
boolean
C0007131 (UMLS CUI [1])
progression on platinum-based regimen
Item
progressed while on or after treatment on platinum-based regimen
boolean
C0242656 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
C0008838 (UMLS CUI [1,3])
prior cytotoxic chemotherapy regimen
Item
patients may not have had more than one prior cytotoxic chemotherapy regimen
boolean
C1514457 (UMLS CUI [1])
tumor stage
Item
stage iv or iiib
boolean
C0441772 (UMLS CUI [1,1])
C0456599 (UMLS CUI [1,2])
age
Item
age at least 18 years
boolean
C0001779 (UMLS CUI [1])
liver and kidney function
Item
adequate liver and kidney function
boolean
C0232741 (UMLS CUI [1,1])
C0232804 (UMLS CUI [1,2])
bone marrow function
Item
adequate bone marrow function
boolean
C1254358 (UMLS CUI [1,1])
C0005953 (UMLS CUI [1,2])
pregnancy or lactation
Item
pregnancy or lactation
boolean
C0032961 (UMLS CUI [1,1])
C0006147 (UMLS CUI [1,2])
unstable medical conditions
Item
unstable medical conditions
boolean
C1142435 (UMLS CUI [1])
concurrent medication
Item
chemotherapy, hormonal therapy, radiotherapy, radiopharmaceuticals or immunotherapy within 3 weeks of tlk286
boolean
C0392920 (UMLS CUI [1])
C0279025 (UMLS CUI [2])
C1522449 (UMLS CUI [3])
C0021083 (UMLS CUI [4,1])
C1258106 (UMLS CUI [4,2])
cns metastasis
Item
cns metastasis unless controlled by treatment
boolean
C0686377 (UMLS CUI [1])