diffuse large b-cell lymphoma
Item
patient with diffuse large b-cell lymphoma according to the who classification (anti cd20 labeling)
boolean
C0079744 (UMLS CUI [1])
age
Item
aged from 60 to 65 years.
boolean
C0001779 (UMLS CUI [1])
previous treatment
Item
not previously treated.
boolean
C0087111 (UMLS CUI [1])
ann arbor stage
Item
ann arbor stage ii, iii, iv.
boolean
C0432516 (UMLS CUI [1])
ecog performance status
Item
ecog performance status 0 to 2.
boolean
C1520224 (UMLS CUI [1])
life expectancy
Item
minimum life expectancy of 3 months.
boolean
C0023671 (UMLS CUI [1])
serologies test
Item
negative hiv, hepatitis b virus (hbv) and hepatitis c virus (hcv) serologies test 4 weeks (except after vaccination).
boolean
C0019698 (UMLS CUI [1])
C0853319 (UMLS CUI [2])
C0201485 (UMLS CUI [3])
written informed consent
Item
having previously signed a written informed consent.
boolean
C0021430 (UMLS CUI [1])
t-cell lymphoma
Item
t-cell lymphoma.
boolean
C0079772 (UMLS CUI [1])
indolent lymphoma
Item
any history of treated or non-treated indolent lymphoma. however, patients not previously diagnosed and having a diffuse large b-cell lymphoma with some small cell infiltration in bone marrow or lymph node may be included.
boolean
C1334170 (UMLS CUI [1])
central nervous system involvement
Item
central nervous system or meningeal involvement by lymphoma.
boolean
C0449389 (UMLS CUI [1])
C2213017 (UMLS CUI [2])
contraindication chemotherapy
Item
contra-indication to any drug contained in the chemotherapy regimens.
boolean
C1301624 (UMLS CUI [1,1])
C0392920 (UMLS CUI [1,2])
serious active disease
Item
any serious active disease (according to the investigator’s decision).
boolean
C0009488 (UMLS CUI [1])
abnormalities
Item
poor renal function (creatinine level>150micromol/l), poor hepatic function (total bilirubin level>30mmol/l, transaminases>2.5 maximum normal level) unless these abnormalities are related to the lymphoma.
boolean
C0201976 (UMLS CUI [1])
C1278039 (UMLS CUI [2])
C0002594 (UMLS CUI [3])
poor bone marrow reserve
Item
poor bone marrow reserve as defined by neutrophils<1.5g/l or platelets<100g/l, unless related to bone marrow infiltration.
boolean
C0948762 (UMLS CUI [1])
C0005821 (UMLS CUI [2])
history of cancer
Item
any history of cancer during the last 5 years with the exception of non-melanoma skin tumors or stage 0 (in situ) cervical carcinoma.
boolean
C0006826 (UMLS CUI [1])
investigational drug
Item
treatment with any investigational drug within 30 days before planned first cycle of chemotherapy and during the study.
boolean
C2348568 (UMLS CUI [1])
tutelage
Item
adult patient under tutelage.
boolean