prostate cancer
Item
diagnosis of prostate cancer
boolean
C0600139 (UMLS CUI [1])
disease progression
Item
progression following prostatectomy or radiation to the prostate, defined as 3 psa rises, with each psa determination at least 4 weeks apart
boolean
C0242656 (UMLS CUI [1])
C0138741 (UMLS CUI [2])
C0033573 (UMLS CUI [3,1])
C1522449 (UMLS CUI [3,2])
psa
Item
psa greater than or equal to 1.0 for men who had a prostatectomy
boolean
C0138741 (UMLS CUI [1])
psa radiation therapy
Item
psa greater than or equal to 3.0 for men who were treated with primary radiation therapy (external beam and/or brachytherapy)
boolean
C0138741 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
psa doubling time
Item
psa doubling time between 6 and 24 months
boolean
C0138741 (UMLS CUI [1,1])
C1521828 (UMLS CUI [1,2])
C1518823 (UMLS CUI [1,3])
fully active and asymptomatic
Item
participants must be either fully active and asymptomatic or symptomatic but fully ambulatory
boolean
C0205177 (UMLS CUI [1])
C0231221 (UMLS CUI [2])
bone marrow function
Item
adequate bone marrow function, kidney function and liver function as evidenced by laboratory results
boolean
C0005953 (UMLS CUI [1])
C0232804 (UMLS CUI [2])
C0232741 (UMLS CUI [3])
metastatic disease
Item
evidence of metastatic disease
boolean
C0027627 (UMLS CUI [1])
hormonal therapy
Item
prior hormonal therapy for recurrent prostate cancer
boolean
C0279025 (UMLS CUI [1,1])
C0278838 (UMLS CUI [1,2])
chemotherapy
Item
prior chemotherapy for recurrent or metastatic prostate cancer
boolean
C0392920 (UMLS CUI [1])
radiation therapy
Item
radiation therapy within 6 months
boolean
C1522449 (UMLS CUI [1])
allergy to nsaids
Item
patients allergic to non-steroidal anti-inflammatory drugs (nsaids), salicylates or sulfonamide-type medications who experience asthma or urticaria (hives) after taking aspirin or other nsaids
boolean
C0020517 (UMLS CUI [1,1])
C0003211 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C0036077 (UMLS CUI [2,2])
aspirin
Item
patients taking a dose of aspirin greater than or equal to 325 mg a day within 4 weeks of study entry
boolean
C0004057 (UMLS CUI [1,1])
C0178602 (UMLS CUI [1,2])
selective cox-2 inhibitors
Item
patients taking selective cox-2 inhibitors or any nsaids other than aspirin within 8 weeks of study entry
boolean
C1257954 (UMLS CUI [1])
fluconazole lithium or warfarin
Item
patients taking fluconazole, lithium or warfarin
boolean
C0016277 (UMLS CUI [1])
C0023870 (UMLS CUI [2])
C0043031 (UMLS CUI [3])
ulceration or bleeding
Item
history of gastrointestinal or abdominal ulceration or any history of significant gastrointestinal bleeding in the past 12 months
boolean
C0237938 (UMLS CUI [1])
C0017181 (UMLS CUI [2])
myocardial infarction
Item
any history of myocardial infarction in the past 12 months
boolean
C0027051 (UMLS CUI [1])
serious medical or psychiatric illness
Item
any uncontrolled, serious medical or psychiatric illness
boolean
C0009488 (UMLS CUI [1])