Non-Small Cell Lung Carcinoma | FDG-Positron Emission Tomography
Item
patients with fdg-avid (radioactive glucose) and pathologically proven stage iia-iib or iiia-iiib non-small cell lung cancer (according to ajcc [american joint committee on cancer] staging, 7th edition).
boolean
C0007131 (UMLS CUI [1])
C3641247 (UMLS CUI [2])
Malignant Neoplasms | EGFR-TKI Sensitizing Mutation | ALK gene Rearrangement
Item
patients with tumors that harbor either egfr sensitizing mutations or alk rearrangement.
boolean
C0006826 (UMLS CUI [1])
C3273083 (UMLS CUI [2])
C1332080 (UMLS CUI [3,1])
C0017287 (UMLS CUI [3,2])
unresectable | Inoperable | Operative Surgical Procedures
Item
patients must be considered unresectable or medically inoperable; patients who decline surgery are also eligible.
boolean
C1519810 (UMLS CUI [1])
C0205187 (UMLS CUI [2])
C0543467 (UMLS CUI [3])
Age
Item
patients must be 18 years of age or older.
boolean
C0001779 (UMLS CUI [1])
ECOG performance status
Item
patients with ecog (eastern cooperative oncology group) performance status of 0-2.
boolean
C1520224 (UMLS CUI [1])
organ function
Item
patients must have adequate organ function.
boolean
C0678852 (UMLS CUI [1])
Able to swallow oral medication
Item
patients must be able to take oral medications.
boolean
C2712086 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
Childbearing Potential Contraceptive methods
Item
women with reproductive capability must be willing to use effective contraception.
boolean
C3831118 (UMLS CUI [1,1])
C0700589 (UMLS CUI [1,2])
Informed consent
Item
patients must be informed of the investigational nature of this study and sign written informed consent in accordance with institutional and federal guidelines.
boolean
C0021430 (UMLS CUI [1])
Compliance behavior Study Protocol
Item
patients must be willing to comply with study procedures.
boolean
C1321605 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
Malignant Neoplasms Component Carcinoma, Small Cell
Item
patients with tumors that have a component of small cell carcinoma.
boolean
C0006826 (UMLS CUI [1,1])
C1705248 (UMLS CUI [1,2])
C0262584 (UMLS CUI [1,3])
Malignant Neoplasms | TNM clinical staging | Pleural Effusion, Malignant | Malignant pericardial effusion
Item
patients wtih stage i, ii, or iv disease, including malignant pleural or pericardial effusion.
boolean
C0006826 (UMLS CUI [1])
C3258246 (UMLS CUI [2])
C0080032 (UMLS CUI [3])
C0220655 (UMLS CUI [4])
prior radiation therapy Chest
Item
prior radiotherapy to the thorax such that composite radiation would significantly over-dose critical structures, either per estimation of the treating radiation oncologist or defined by failure to meet normal tissue tolerance constraints.
boolean
C0279134 (UMLS CUI [1,1])
C0817096 (UMLS CUI [1,2])
Chest Therapeutic radiology procedure Unable | Targeted Therapy Unable
Item
patients who cannot tolerate thoracic radiotherapy or targeted therapy.
boolean
C0817096 (UMLS CUI [1,1])
C1522449 (UMLS CUI [1,2])
C1299582 (UMLS CUI [1,3])
C2985566 (UMLS CUI [2,1])
C1299582 (UMLS CUI [2,2])
Prior diagnosis Lung Diseases, Interstitial | Prior diagnosis Pulmonary Fibrosis
Item
patients wtih a prior diagnosis of interstitial lung disease or pulmonary fibrosis.
boolean
C0332132 (UMLS CUI [1,1])
C0206062 (UMLS CUI [1,2])
C0332132 (UMLS CUI [2,1])
C0034069 (UMLS CUI [2,2])
Able to swallow oral medication | Intravenous Feeding | Operative Surgical Procedures Affecting Gastrointestinal Absorption | Peptic Ulcer
Item
patients who cannot take oral medication, require intravenous alimentation, had prior surgical procedures affecting gastrointestinal absorption, or have active peptic ulcer disease.
boolean
C2712086 (UMLS CUI [1,1])
C0175795 (UMLS CUI [1,2])
C0021910 (UMLS CUI [2])
C0543467 (UMLS CUI [3,1])
C0392760 (UMLS CUI [3,2])
C3714657 (UMLS CUI [3,3])
C0030920 (UMLS CUI [4])
Hypersensitivity erlotinib | Hypersensitivity crizotinib | Hypersensitivity Pharmaceutical Excipient
Item
hypersensitivity to erlotinib, crizotinib, or to any of the excipients.
boolean
C0020517 (UMLS CUI [1,1])
C1135135 (UMLS CUI [1,2])
C0020517 (UMLS CUI [2,1])
C2974289 (UMLS CUI [2,2])
C0020517 (UMLS CUI [3,1])
C0015237 (UMLS CUI [3,2])
Pregnancy | Therapeutic radiology procedure Teratogenic effect | Therapeutic radiology procedure Abortifacient Effect
Item
pregnant women are excluded from this study because radiation has the potential for teratogenic or abortifacient effects.
boolean
C0032961 (UMLS CUI [1])
C1522449 (UMLS CUI [2,1])
C0232910 (UMLS CUI [2,2])
C1522449 (UMLS CUI [3,1])
C3179338 (UMLS CUI [3,2])
Prisoners
Item
prisoners are excluded from this study.
boolean
C0033167 (UMLS CUI [1])