AML
Item
diagnosis of acute myeloid leukemia
boolean
C0023467 (UMLS CUI [1])
untreated disease
Item
previously untreated disease
boolean
C0009488 (UMLS CUI [1])
hydroxyurea or corticosteroids
Item
previous hydroxyurea and/or corticosteroids are acceptable
boolean
C0020402 (UMLS CUI [1])
C0001617 (UMLS CUI [2])
hematologic disorder
Item
no preexisting history of a hematologic disorder
boolean
C0018939 (UMLS CUI [1,1])
C0332152 (UMLS CUI [1,2])
myelodysplastic
Item
myelodysplastic features allowed
boolean
C3463824 (UMLS CUI [1])
no secondary acute leukemia
Item
no acute leukemia secondary to previous therapy
boolean
C0280449 (UMLS CUI [1])
leukemic meningitis
Item
no leukemic meningitis
boolean
C0948840 (UMLS CUI [1])
bilirubin
Item
bilirubin < 2.0 mg/dl (unless felt to be increased because of hepatic infiltration with leukemia)
boolean
C0005437 (UMLS CUI [1])
creatinine
Item
creatinine < 2.0 mg/dl
boolean
C0010294 (UMLS CUI [1])
pregnant or lactating
Item
pregnant or lactating patients are ineligible
boolean
C0032961 (UMLS CUI [1])
C0006147 (UMLS CUI [2])
effective contraception
Item
fertile patients must use effective contraception
boolean
C0700589 (UMLS CUI [1])
active congestive heart failure
Item
no history of or active congestive heart failure
boolean
C0018802 (UMLS CUI [1])
concurrent therapy
Item
prior concurrent therapy: see disease characteristics
boolean
C0087111 (UMLS CUI [1])